MIT faculty members Nancy Kanwisher, Robert Langer, and Sara Seager are among eight researchers worldwide to receive this year’s Kavli Prizes.

A partnership among the Norwegian Academy of Science and Letters, the Norwegian Ministry of Education and Research, and the Kavli Foundation, the Kavli Prizes are awarded every two years to “honor scientists for breakthroughs in astrophysics, nanoscience and neuroscience that transform our understanding of the big, the small and the complex.” The laureates in each field will share $1 million.

Understanding recognition of faces

Nancy Kanwisher, the Walter A Rosenblith Professor of Brain and Cognitive Sciences and McGovern Institute for Brain Research investigator, has been awarded the 2024 Kavli Prize in Neuroscience with Doris Tsao, professor in the Department of Molecular and Cell Biology at the University of California at Berkeley, and Winrich Freiwald, the Denise A. and Eugene W. Chinery Professor at the Rockefeller University.

Kanwisher, Tsao, and Freiwald discovered a specialized system within the brain to recognize faces. Their discoveries have provided basic principles of neural organization and made the starting point for further research on how the processing of visual information is integrated with other cognitive functions.

Kanwisher was the first to prove that a specific area in the human neocortex is dedicated to recognizing faces, now called the fusiform face area. Using functional magnetic resonance imaging, she found individual differences in the location of this area and devised an analysis technique to effectively localize specialized functional regions in the brain. This technique is now widely used and applied to domains beyond the face recognition system. 

Integrating nanomaterials for biomedical advances

Robert Langer, the David H. Koch Institute Professor, has been awarded the 2024 Kavli Prize in Nanoscience with Paul Alivisatos, president of the University of Chicago and John D. MacArthur Distinguished Service Professor in the Department of Chemistry, and Chad Mirkin, professor of chemistry at Northwestern University.

Langer, Alivisatos, and Mirkin each revolutionized the field of nanomedicine by demonstrating how engineering at the nano scale can advance biomedical research and application. Their discoveries contributed foundationally to the development of therapeutics, vaccines, bioimaging, and diagnostics.

Langer was the first to develop nanoengineered materials that enabled the controlled release, or regular flow, of drug molecules. This capability has had an immense impact for the treatment of a range of diseases, such as aggressive brain cancer, prostate cancer, and schizophrenia. His work also showed that tiny particles, containing protein antigens, can be used in vaccination, and was instrumental in the development of the delivery of messenger RNA vaccines. 

Searching for life beyond Earth

Sara Seager, the Class of 1941 Professor of Planetary Sciences in the Department of Earth, Atmospheric and Planetary Sciences and a professor in the departments of Physics and of Aeronautics and Astronautics, has been awarded the 2024 Kavli Prize in Astrophysics along with David Charbonneau, the Fred Kavli Professor of Astrophysics at Harvard University.

Seager and Charbonneau are recognized for discoveries of exoplanets and the characterization of their atmospheres. They pioneered methods for the detection of atomic species in planetary atmospheres and the measurement of their thermal infrared emission, setting the stage for finding the molecular fingerprints of atmospheres around both giant and rocky planets. Their contributions have been key to the enormous progress seen in the last 20 years in the exploration of myriad exoplanets. 

Kanwisher, Langer, and Seager bring the number of all-time MIT faculty recipients of the Kavli Prize to eight. Prior winners include Rainer Weiss in astrophysics (2016), Alan Guth in astrophysics (2014), Mildred Dresselhaus in nanoscience (2012), Ann Graybiel in neuroscience (2012), and Jane Luu in astrophysics (2012).

Physics graduate student Jeong Min (Jane) Park is among the 32 exceptional early-career scientists worldwide chosen to receive the prestigious 2024 Schmidt Science Fellows award.  

As a 2024 Schmidt Science Fellow, Park’s postdoctoral work will seek to directly detect phases that could host new particles by employing an instrument that can visualize subatomic-scale phenomena.  

With her advisor, Pablo Jarillo-Herrero, the Cecil and Ida Green Professor of Physics, Park’s research at MIT focuses on discovering novel quantum phases of matter.

“When there are many electrons in a material, their interactions can lead to collective behaviors that are not expected from individual particles, known as emergent phenomena,” explains Park. “One example is superconductivity, where interacting electrons combine together as a pair at low temperatures to conduct electricity without energy loss.”

During her PhD studies, she has investigated novel types of superconductivity by designing new materials with targeted interactions and topology. In particular, she used graphene, atomically thin two-dimensional layers of graphite, the same material as pencil lead, and turned it into a “magic” material. This so-called magic-angle twisted trilayer graphene provided an extraordinarily strong form of superconductivity that is robust under high magnetic fields. Later, she found a whole “magic family” of these materials, elucidating the key mechanisms behind superconductivity and interaction-driven phenomena. These results have provided a new platform to study emergent phenomena in two dimensions, which can lead to innovations in electronics and quantum technology.

Park says she is looking forward to her postdoctoral studies with Princeton University physics professor Ali Yazdani's lab.

“I’m excited about the idea of discovering and studying new quantum phenomena that could further the understanding of fundamental physics,” says Park. “Having explored interaction-driven phenomena through the design of new materials, I’m now aiming to broaden my perspective and expertise to address a different kind of question, by combining my background in material design with the sophisticated local-scale measurements that I will adopt during my postdoc.”

She explains that elementary particles are classified as either bosons or fermions, with contrasting behaviors upon interchanging two identical particles, referred to as exchange statistics; bosons remain unchanged, while fermions acquire a minus sign in their quantum wavefunction.

Theories predict the existence of fundamentally different particles known as non-abelian anyons, whose wavefunctions braid upon particle exchange. Such a braiding process can be used to encode and store information, potentially opening the door to fault-tolerant quantum computing in the future.

Since 2018, this prestigious postdoctoral program has sought to break down silos among scientific fields to solve the world’s biggest challenges and support future leaders in STEM.

Schmidt Science Fellows, an initiative of Schmidt Sciences, delivered in partnership with the Rhodes Trust, identifies, develops, and amplifies the next generation of science leaders, by building a community of scientists and supporters of interdisciplinary science and leveraging this network to drive sector-wide change. The 2024 fellows consist of 17 nationalities across North America, Europe, and Asia.   

Nominated candidates undergo a rigorous selection process that includes a paper-based academic review with panels of experts in their home disciplines and final interviews with panels, including senior representatives from across many scientific disciplines and different business sectors.  

John Joannopoulos, an innovator and mentor in the fields of theoretical condensed matter physics and nanophotonics, has been named the recipient of the 2024-2025 James R. Killian Jr. Faculty Achievement Award.

Joannopoulos is the Francis Wright Davis Professor of Physics and director of MIT’s Institute for Soldier Nanotechnologies. He has been a member of the MIT faculty for 50 years.

“Professor Joannopoulos’s profound and lasting impact on the field of theoretical condensed matter physics finds its roots in his pioneering work in harnessing ab initio physics to elucidate the behavior of materials at the atomic level,” states the award citation, which was announced at today’s faculty meeting by Roger White, chair of the Killian Award Selection Committee and professor of philosophy at MIT. “His seminal research in the development of photonic crystals has revolutionized understanding of light-matter interactions, laying the groundwork for transformative advancements in diverse fields ranging from telecommunications to biomedical engineering.”

The award also honors Joannopoulos’ service as a “legendary mentor to generations of students, inspiring them to achieve excellence in science while at the same time facilitating the practical benefit to society through entrepreneurship.”

The Killian Award was established in 1971 to recognize outstanding professional contributions by MIT faculty members. It is the highest honor that the faculty can give to one of its members.

“I have to tell you, it was a complete and utter surprise,” Joannopoulos told MIT News shortly after he received word of the award. “I didn’t expect it at all, and was extremely flattered, honored, and moved by it, frankly.”

Joannopoulous has spent his entire professional career at MIT. He came to the Institute in 1974, directly after receiving his PhD in physics at the University of California at Berkeley, where he also earned his bachelor’s degree. Starting out as an assistant professor in MIT’s Department of Physics, he quickly set up a research program focused on theoretical condensed matter physics.

Over the first half of his MIT career, Joannopoulos worked to elucidate the fundamental nature of the electronic, vibrational, and optical structure of crystalline and amorphous bulk solids, their surfaces, interfaces, and defects. He and his students developed numerous theoretical methods to enable tractable and accurate calculations of these complex systems.

In the 1990s, his work with microscopic material systems expanded to a new class of materials, called photonic crystals — materials that could be engineered at the micro- and nanoscale to manipulate light in ways that impart surprising and exotic optical qualities to the material as a whole.

“I saw that you could create photonic crystals with defects that can affect the properties of photons, in much the same way that defects in a semiconductor affect the properties of electrons,” Joannopoulos says. “So I started working in this area to try and explore what anomalous light phenomena can we discover using this approach?”

Among his various breakthroughs in the field was the realization of a “perfect dielectric mirror” — a multilayered optical device that reflects light from all angles as normal metallic mirrors do, and that can also be tuned to reflect and trap light at specific frequencies. He and his colleagues saw potential for the mirror to be made into a hollow fiber that could serve as a highly effective optical conduit, for use in a wide range of applications. To further advance the technology, he and his colleagues launched a startup, which has since developed the technology into a flexible, fiber-optic “surgical scalpel.”

Throughout his career, Joannopoulos has helped to launch numerous startups and photonics-based technologies.

“His ability to bridge the gap between academia and industry has not only advanced scientific knowledge but also led to the creation of dozens of new companies, thousands of jobs, and groundbreaking products that continue to benefit society to this day,” the award citation states.

In 2006, Joannopoulos accepted the position as director of MIT’s Institute for Soldier Nanotechnologies (ISN), a collaboration between MIT researchers, industry partners, and military defense experts, who seek innovations to protect and enhance soldiers’ survivability in the field. In his role as ISN head, Joannopoulos has worked across MIT, making connections and supporting new projects with researchers specializing in fields far from his own.

“I get a chance to explore and learn fascinating new things,” says Joannopoulos, who is currently overseeing projects related to hyperspectral imaging, smart and responsive fabrics, and nanodrug delivery. “I love that aspect of really getting to understand what people in other fields are doing. And they’re doing great work across many, many different fields.”

Throughout his career at MIT, Joannopoulos has been especially inspired and motivated by his students, many of whom have gone on to found companies, lead top academic and research institutions, and make significant contributions to their respective fields, including one student who was awarded the Nobel Prize in Physics in 1998.

“One’s proudest moments are the successes of one’s students, and in that regard, I’ve been extremely lucky to have had truly exceptional students over the years,” Joannopolous says.

His many contributions to academia and industry have earned Joannopoulos numerous honors and awards, including his election to both the National Academy of Sciences and the American Academy of Arts and Sciences. He is also a fellow of both the American Physical Society and the American Association for the Advancement of Science.

“The Selection Committee is delighted to have this opportunity to honor Professor John Joannopoulos: a visionary scientist, a beloved mentor, a great believer in the goodness of people, and a leader whose contributions to MIT and the broader scientific community are immeasurable,” the award citation concludes.

When Paula Hammond first arrived on MIT’s campus as a first-year student in the early 1980s, she wasn’t sure if she belonged. In fact, as she told an MIT audience yesterday, she felt like “an imposter.”

However, that feeling didn’t last long, as Hammond began to find support among her fellow students and MIT’s faculty. “Community was really important for me, to feel that I belonged, to feel that I had a place here, and I found people who were willing to embrace me and support me,” she said.

Hammond, a world-renowned chemical engineer who has spent most of her academic career at MIT, made her remarks during the 2023-24 James R. Killian Jr. Faculty Achievement Award lecture.

Established in 1971 to honor MIT’s 10th president, James Killian, the Killian Award recognizes extraordinary professional achievements by an MIT faculty member. Hammond was chosen for this year’s award “not only for her tremendous professional achievements and contributions, but also for her genuine warmth and humanity, her thoughtfulness and effective leadership, and her empathy and ethics,” according to the award citation.

“Professor Hammond is a pioneer in nanotechnology research. With a program that extends from basic science to translational research in medicine and energy, she has introduced new approaches for the design and development of complex drug delivery systems for cancer treatment and noninvasive imaging,” said Mary Fuller, chair of MIT’s faculty and a professor of literature, who presented the award. “As her colleagues, we are delighted to celebrate her career today.”

In January, Hammond began serving as MIT’s vice provost for faculty. Before that, she chaired the Department of Chemical Engineering for eight years, and she was named an Institute Professor in 2021.

A versatile technique

Hammond, who grew up in Detroit, credits her parents with instilling a love of science. Her father was one of very few Black PhDs in biochemistry at the time, while her mother earned a master’s degree in nursing from Howard University and founded the nursing school at Wayne County Community College. “That provided a huge amount of opportunity for women in the area of Detroit, including women of color,” Hammond noted.

After earning her bachelor’s degree from MIT in 1984, Hammond worked as an engineer before returning to the Institute as a graduate student, earning her PhD in 1993. After a two-year postdoc at Harvard University, she returned to join the MIT faculty in 1995.

At the heart of Hammond’s research is a technique she developed to create thin films that can essentially “shrink-wrap” nanoparticles. By tuning the chemical composition of these films, the particles can be customized to deliver drugs or nucleic acids and to target specific cells in the body, including cancer cells.

To make these films, Hammond begins by layering positively charged polymers onto a negatively charged surface. Then, more layers can be added, alternating positively and negatively charged polymers. Each of these layers may contain drugs or other useful molecules, such as DNA or RNA. Some of these films contain hundreds of layers, others just one, making them useful for a wide range of applications.

“What’s nice about the layer-by-layer process is I can choose a group of degradable polymers that are nicely biocompatible, and I can alternate them with our drug materials. This means that I can build up thin film layers that contain different drugs at different points within the film,” Hammond said. “Then, when the film degrades, it can release those drugs in reverse order. This is enabling us to create complex, multidrug films, using a simple water-based technique.”

Hammond described how these layer-by-layer films can be used to promote bone growth, in an application that could help people born with congenital bone defects or people who experience traumatic injuries.

For that use, her lab has created films with layers of two proteins. One of these, BMP-2, is a protein that interacts with adult stem cells and induces them to differentiate into bone cells, generating new bone. The second is a growth factor called VEGF, which stimulates the growth of new blood vessels that help bone to regenerate. These layers are applied to a very thin tissue scaffold that can be implanted at the injury site.

Hammond and her students designed the coating so that once implanted, it would release VEGF early, over a week or so, and continue releasing BMP-2 for up to 40 days. In a study of mice, they found that this tissue scaffold stimulated the growth of new bone that was nearly indistinguishable from natural bone.

Targeting cancer

As a member of MIT’s Koch Institute for Integrative Cancer Research, Hammond has also developed layer-by-layer coatings that can improve the performance of nanoparticles used for cancer drug delivery, such as liposomes or nanoparticles made from a polymer called PLGA.

“We have a broad range of drug carriers that we can wrap this way. I think of them like a gobstopper, where there are all those different layers of candy and they dissolve one at a time,” Hammond said.

Using this approach, Hammond has created particles that can deliver a one-two punch to cancer cells. First, the particles release a dose of a nucleic acid such as short interfering RNA (siRNA), which can turn off a cancerous gene, or microRNA, which can activate tumor suppressor genes. Then, the particles release a chemotherapy drug such as cisplatin, to which the cells are now more vulnerable.

The particles also include a negatively charged outer “stealth layer” that protects them from being broken down in the bloodstream before they can reach their targets. This outer layer can also be modified to help the particles get taken up by cancer cells, by incorporating molecules that bind to proteins that are abundant on tumor cells.

In more recent work, Hammond has begun developing nanoparticles that can target ovarian cancer and help prevent recurrence of the disease after chemotherapy. In about 70 percent of ovarian cancer patients, the first round of treatment is highly effective, but tumors recur in about 85 percent of those cases, and these new tumors are usually highly drug resistant.

By altering the type of coating applied to drug-delivering nanoparticles, Hammond has found that the particles can be designed to either get inside tumor cells or stick to their surfaces. Using particles that stick to the cells, she has designed a treatment that could help to jumpstart a patient’s immune response to any recurrent tumor cells.

“With ovarian cancer, very few immune cells exist in that space, and because they don’t have a lot of immune cells present, it’s very difficult to rev up an immune response,” she said. “However, if we can deliver a molecule to neighboring cells, those few that are present, and get them revved up, then we might be able to do something.”

To that end, she designed nanoparticles that deliver IL-12, a cytokine that stimulates nearby T cells to spring into action and begin attacking tumor cells. In a study of mice, she found that this treatment induced a long-term memory T-cell response that prevented recurrence of ovarian cancer.

Hammond closed her lecture by describing the impact that the Institute has had on her throughout her career.

“It’s been a transformative experience,” she said. “I really think of this place as special because it brings people together and enables us to do things together that we couldn’t do alone. And it is that support we get from our friends, our colleagues, and our students that really makes things possible.”

MIT faculty members Nancy Kanwisher, Robert Langer, and Sara Seager are among eight researchers worldwide to receive this year’s Kavli Prizes.

A partnership among the Norwegian Academy of Science and Letters, the Norwegian Ministry of Education and Research, and the Kavli Foundation, the Kavli Prizes are awarded every two years to “honor scientists for breakthroughs in astrophysics, nanoscience and neuroscience that transform our understanding of the big, the small and the complex.” The laureates in each field will share $1 million.

Understanding recognition of faces

Nancy Kanwisher, the Walter A Rosenblith Professor of Brain and Cognitive Sciences and McGovern Institute for Brain Research investigator, has been awarded the 2024 Kavli Prize in Neuroscience with Doris Tsao, professor in the Department of Molecular and Cell Biology at the University of California at Berkeley, and Winrich Freiwald, the Denise A. and Eugene W. Chinery Professor at the Rockefeller University.

Kanwisher, Tsao, and Freiwald discovered a specialized system within the brain to recognize faces. Their discoveries have provided basic principles of neural organization and made the starting point for further research on how the processing of visual information is integrated with other cognitive functions.

Kanwisher was the first to prove that a specific area in the human neocortex is dedicated to recognizing faces, now called the fusiform face area. Using functional magnetic resonance imaging, she found individual differences in the location of this area and devised an analysis technique to effectively localize specialized functional regions in the brain. This technique is now widely used and applied to domains beyond the face recognition system. 

Integrating nanomaterials for biomedical advances

Robert Langer, the David H. Koch Institute Professor, has been awarded the 2024 Kavli Prize in Nanoscience with Paul Alivisatos, president of the University of Chicago and John D. MacArthur Distinguished Service Professor in the Department of Chemistry, and Chad Mirkin, professor of chemistry at Northwestern University.

Langer, Alivisatos, and Mirkin each revolutionized the field of nanomedicine by demonstrating how engineering at the nano scale can advance biomedical research and application. Their discoveries contributed foundationally to the development of therapeutics, vaccines, bioimaging, and diagnostics.

Langer was the first to develop nanoengineered materials that enabled the controlled release, or regular flow, of drug molecules. This capability has had an immense impact for the treatment of a range of diseases, such as aggressive brain cancer, prostate cancer, and schizophrenia. His work also showed that tiny particles, containing protein antigens, can be used in vaccination, and was instrumental in the development of the delivery of messenger RNA vaccines. 

Searching for life beyond Earth

Sara Seager, the Class of 1941 Professor of Planetary Sciences in the Department of Earth, Atmospheric and Planetary Sciences and a professor in the departments of Physics and of Aeronautics and Astronautics, has been awarded the 2024 Kavli Prize in Astrophysics along with David Charbonneau, the Fred Kavli Professor of Astrophysics at Harvard University.

Seager and Charbonneau are recognized for discoveries of exoplanets and the characterization of their atmospheres. They pioneered methods for the detection of atomic species in planetary atmospheres and the measurement of their thermal infrared emission, setting the stage for finding the molecular fingerprints of atmospheres around both giant and rocky planets. Their contributions have been key to the enormous progress seen in the last 20 years in the exploration of myriad exoplanets. 

Kanwisher, Langer, and Seager bring the number of all-time MIT faculty recipients of the Kavli Prize to eight. Prior winners include Rainer Weiss in astrophysics (2016), Alan Guth in astrophysics (2014), Mildred Dresselhaus in nanoscience (2012), Ann Graybiel in neuroscience (2012), and Jane Luu in astrophysics (2012).

Physics graduate student Jeong Min (Jane) Park is among the 32 exceptional early-career scientists worldwide chosen to receive the prestigious 2024 Schmidt Science Fellows award.  

As a 2024 Schmidt Science Fellow, Park’s postdoctoral work will seek to directly detect phases that could host new particles by employing an instrument that can visualize subatomic-scale phenomena.  

With her advisor, Pablo Jarillo-Herrero, the Cecil and Ida Green Professor of Physics, Park’s research at MIT focuses on discovering novel quantum phases of matter.

“When there are many electrons in a material, their interactions can lead to collective behaviors that are not expected from individual particles, known as emergent phenomena,” explains Park. “One example is superconductivity, where interacting electrons combine together as a pair at low temperatures to conduct electricity without energy loss.”

During her PhD studies, she has investigated novel types of superconductivity by designing new materials with targeted interactions and topology. In particular, she used graphene, atomically thin two-dimensional layers of graphite, the same material as pencil lead, and turned it into a “magic” material. This so-called magic-angle twisted trilayer graphene provided an extraordinarily strong form of superconductivity that is robust under high magnetic fields. Later, she found a whole “magic family” of these materials, elucidating the key mechanisms behind superconductivity and interaction-driven phenomena. These results have provided a new platform to study emergent phenomena in two dimensions, which can lead to innovations in electronics and quantum technology.

Park says she is looking forward to her postdoctoral studies with Princeton University physics professor Ali Yazdani's lab.

“I’m excited about the idea of discovering and studying new quantum phenomena that could further the understanding of fundamental physics,” says Park. “Having explored interaction-driven phenomena through the design of new materials, I’m now aiming to broaden my perspective and expertise to address a different kind of question, by combining my background in material design with the sophisticated local-scale measurements that I will adopt during my postdoc.”

She explains that elementary particles are classified as either bosons or fermions, with contrasting behaviors upon interchanging two identical particles, referred to as exchange statistics; bosons remain unchanged, while fermions acquire a minus sign in their quantum wavefunction.

Theories predict the existence of fundamentally different particles known as non-abelian anyons, whose wavefunctions braid upon particle exchange. Such a braiding process can be used to encode and store information, potentially opening the door to fault-tolerant quantum computing in the future.

Since 2018, this prestigious postdoctoral program has sought to break down silos among scientific fields to solve the world’s biggest challenges and support future leaders in STEM.

Schmidt Science Fellows, an initiative of Schmidt Sciences, delivered in partnership with the Rhodes Trust, identifies, develops, and amplifies the next generation of science leaders, by building a community of scientists and supporters of interdisciplinary science and leveraging this network to drive sector-wide change. The 2024 fellows consist of 17 nationalities across North America, Europe, and Asia.   

Nominated candidates undergo a rigorous selection process that includes a paper-based academic review with panels of experts in their home disciplines and final interviews with panels, including senior representatives from across many scientific disciplines and different business sectors.  

John Joannopoulos, an innovator and mentor in the fields of theoretical condensed matter physics and nanophotonics, has been named the recipient of the 2024-2025 James R. Killian Jr. Faculty Achievement Award.

Joannopoulos is the Francis Wright Davis Professor of Physics and director of MIT’s Institute for Soldier Nanotechnologies. He has been a member of the MIT faculty for 50 years.

“Professor Joannopoulos’s profound and lasting impact on the field of theoretical condensed matter physics finds its roots in his pioneering work in harnessing ab initio physics to elucidate the behavior of materials at the atomic level,” states the award citation, which was announced at today’s faculty meeting by Roger White, chair of the Killian Award Selection Committee and professor of philosophy at MIT. “His seminal research in the development of photonic crystals has revolutionized understanding of light-matter interactions, laying the groundwork for transformative advancements in diverse fields ranging from telecommunications to biomedical engineering.”

The award also honors Joannopoulos’ service as a “legendary mentor to generations of students, inspiring them to achieve excellence in science while at the same time facilitating the practical benefit to society through entrepreneurship.”

The Killian Award was established in 1971 to recognize outstanding professional contributions by MIT faculty members. It is the highest honor that the faculty can give to one of its members.

“I have to tell you, it was a complete and utter surprise,” Joannopoulos told MIT News shortly after he received word of the award. “I didn’t expect it at all, and was extremely flattered, honored, and moved by it, frankly.”

Joannopoulous has spent his entire professional career at MIT. He came to the Institute in 1974, directly after receiving his PhD in physics at the University of California at Berkeley, where he also earned his bachelor’s degree. Starting out as an assistant professor in MIT’s Department of Physics, he quickly set up a research program focused on theoretical condensed matter physics.

Over the first half of his MIT career, Joannopoulos worked to elucidate the fundamental nature of the electronic, vibrational, and optical structure of crystalline and amorphous bulk solids, their surfaces, interfaces, and defects. He and his students developed numerous theoretical methods to enable tractable and accurate calculations of these complex systems.

In the 1990s, his work with microscopic material systems expanded to a new class of materials, called photonic crystals — materials that could be engineered at the micro- and nanoscale to manipulate light in ways that impart surprising and exotic optical qualities to the material as a whole.

“I saw that you could create photonic crystals with defects that can affect the properties of photons, in much the same way that defects in a semiconductor affect the properties of electrons,” Joannopoulos says. “So I started working in this area to try and explore what anomalous light phenomena can we discover using this approach?”

Among his various breakthroughs in the field was the realization of a “perfect dielectric mirror” — a multilayered optical device that reflects light from all angles as normal metallic mirrors do, and that can also be tuned to reflect and trap light at specific frequencies. He and his colleagues saw potential for the mirror to be made into a hollow fiber that could serve as a highly effective optical conduit, for use in a wide range of applications. To further advance the technology, he and his colleagues launched a startup, which has since developed the technology into a flexible, fiber-optic “surgical scalpel.”

Throughout his career, Joannopoulos has helped to launch numerous startups and photonics-based technologies.

“His ability to bridge the gap between academia and industry has not only advanced scientific knowledge but also led to the creation of dozens of new companies, thousands of jobs, and groundbreaking products that continue to benefit society to this day,” the award citation states.

In 2006, Joannopoulos accepted the position as director of MIT’s Institute for Soldier Nanotechnologies (ISN), a collaboration between MIT researchers, industry partners, and military defense experts, who seek innovations to protect and enhance soldiers’ survivability in the field. In his role as ISN head, Joannopoulos has worked across MIT, making connections and supporting new projects with researchers specializing in fields far from his own.

“I get a chance to explore and learn fascinating new things,” says Joannopoulos, who is currently overseeing projects related to hyperspectral imaging, smart and responsive fabrics, and nanodrug delivery. “I love that aspect of really getting to understand what people in other fields are doing. And they’re doing great work across many, many different fields.”

Throughout his career at MIT, Joannopoulos has been especially inspired and motivated by his students, many of whom have gone on to found companies, lead top academic and research institutions, and make significant contributions to their respective fields, including one student who was awarded the Nobel Prize in Physics in 1998.

“One’s proudest moments are the successes of one’s students, and in that regard, I’ve been extremely lucky to have had truly exceptional students over the years,” Joannopolous says.

His many contributions to academia and industry have earned Joannopoulos numerous honors and awards, including his election to both the National Academy of Sciences and the American Academy of Arts and Sciences. He is also a fellow of both the American Physical Society and the American Association for the Advancement of Science.

“The Selection Committee is delighted to have this opportunity to honor Professor John Joannopoulos: a visionary scientist, a beloved mentor, a great believer in the goodness of people, and a leader whose contributions to MIT and the broader scientific community are immeasurable,” the award citation concludes.

When Paula Hammond first arrived on MIT’s campus as a first-year student in the early 1980s, she wasn’t sure if she belonged. In fact, as she told an MIT audience yesterday, she felt like “an imposter.”

However, that feeling didn’t last long, as Hammond began to find support among her fellow students and MIT’s faculty. “Community was really important for me, to feel that I belonged, to feel that I had a place here, and I found people who were willing to embrace me and support me,” she said.

Hammond, a world-renowned chemical engineer who has spent most of her academic career at MIT, made her remarks during the 2023-24 James R. Killian Jr. Faculty Achievement Award lecture.

Established in 1971 to honor MIT’s 10th president, James Killian, the Killian Award recognizes extraordinary professional achievements by an MIT faculty member. Hammond was chosen for this year’s award “not only for her tremendous professional achievements and contributions, but also for her genuine warmth and humanity, her thoughtfulness and effective leadership, and her empathy and ethics,” according to the award citation.

“Professor Hammond is a pioneer in nanotechnology research. With a program that extends from basic science to translational research in medicine and energy, she has introduced new approaches for the design and development of complex drug delivery systems for cancer treatment and noninvasive imaging,” said Mary Fuller, chair of MIT’s faculty and a professor of literature, who presented the award. “As her colleagues, we are delighted to celebrate her career today.”

In January, Hammond began serving as MIT’s vice provost for faculty. Before that, she chaired the Department of Chemical Engineering for eight years, and she was named an Institute Professor in 2021.

A versatile technique

Hammond, who grew up in Detroit, credits her parents with instilling a love of science. Her father was one of very few Black PhDs in biochemistry at the time, while her mother earned a master’s degree in nursing from Howard University and founded the nursing school at Wayne County Community College. “That provided a huge amount of opportunity for women in the area of Detroit, including women of color,” Hammond noted.

After earning her bachelor’s degree from MIT in 1984, Hammond worked as an engineer before returning to the Institute as a graduate student, earning her PhD in 1993. After a two-year postdoc at Harvard University, she returned to join the MIT faculty in 1995.

At the heart of Hammond’s research is a technique she developed to create thin films that can essentially “shrink-wrap” nanoparticles. By tuning the chemical composition of these films, the particles can be customized to deliver drugs or nucleic acids and to target specific cells in the body, including cancer cells.

To make these films, Hammond begins by layering positively charged polymers onto a negatively charged surface. Then, more layers can be added, alternating positively and negatively charged polymers. Each of these layers may contain drugs or other useful molecules, such as DNA or RNA. Some of these films contain hundreds of layers, others just one, making them useful for a wide range of applications.

“What’s nice about the layer-by-layer process is I can choose a group of degradable polymers that are nicely biocompatible, and I can alternate them with our drug materials. This means that I can build up thin film layers that contain different drugs at different points within the film,” Hammond said. “Then, when the film degrades, it can release those drugs in reverse order. This is enabling us to create complex, multidrug films, using a simple water-based technique.”

Hammond described how these layer-by-layer films can be used to promote bone growth, in an application that could help people born with congenital bone defects or people who experience traumatic injuries.

For that use, her lab has created films with layers of two proteins. One of these, BMP-2, is a protein that interacts with adult stem cells and induces them to differentiate into bone cells, generating new bone. The second is a growth factor called VEGF, which stimulates the growth of new blood vessels that help bone to regenerate. These layers are applied to a very thin tissue scaffold that can be implanted at the injury site.

Hammond and her students designed the coating so that once implanted, it would release VEGF early, over a week or so, and continue releasing BMP-2 for up to 40 days. In a study of mice, they found that this tissue scaffold stimulated the growth of new bone that was nearly indistinguishable from natural bone.

Targeting cancer

As a member of MIT’s Koch Institute for Integrative Cancer Research, Hammond has also developed layer-by-layer coatings that can improve the performance of nanoparticles used for cancer drug delivery, such as liposomes or nanoparticles made from a polymer called PLGA.

“We have a broad range of drug carriers that we can wrap this way. I think of them like a gobstopper, where there are all those different layers of candy and they dissolve one at a time,” Hammond said.

Using this approach, Hammond has created particles that can deliver a one-two punch to cancer cells. First, the particles release a dose of a nucleic acid such as short interfering RNA (siRNA), which can turn off a cancerous gene, or microRNA, which can activate tumor suppressor genes. Then, the particles release a chemotherapy drug such as cisplatin, to which the cells are now more vulnerable.

The particles also include a negatively charged outer “stealth layer” that protects them from being broken down in the bloodstream before they can reach their targets. This outer layer can also be modified to help the particles get taken up by cancer cells, by incorporating molecules that bind to proteins that are abundant on tumor cells.

In more recent work, Hammond has begun developing nanoparticles that can target ovarian cancer and help prevent recurrence of the disease after chemotherapy. In about 70 percent of ovarian cancer patients, the first round of treatment is highly effective, but tumors recur in about 85 percent of those cases, and these new tumors are usually highly drug resistant.

By altering the type of coating applied to drug-delivering nanoparticles, Hammond has found that the particles can be designed to either get inside tumor cells or stick to their surfaces. Using particles that stick to the cells, she has designed a treatment that could help to jumpstart a patient’s immune response to any recurrent tumor cells.

“With ovarian cancer, very few immune cells exist in that space, and because they don’t have a lot of immune cells present, it’s very difficult to rev up an immune response,” she said. “However, if we can deliver a molecule to neighboring cells, those few that are present, and get them revved up, then we might be able to do something.”

To that end, she designed nanoparticles that deliver IL-12, a cytokine that stimulates nearby T cells to spring into action and begin attacking tumor cells. In a study of mice, she found that this treatment induced a long-term memory T-cell response that prevented recurrence of ovarian cancer.

Hammond closed her lecture by describing the impact that the Institute has had on her throughout her career.

“It’s been a transformative experience,” she said. “I really think of this place as special because it brings people together and enables us to do things together that we couldn’t do alone. And it is that support we get from our friends, our colleagues, and our students that really makes things possible.”

MIT faculty members Nancy Kanwisher, Robert Langer, and Sara Seager are among eight researchers worldwide to receive this year’s Kavli Prizes.

A partnership among the Norwegian Academy of Science and Letters, the Norwegian Ministry of Education and Research, and the Kavli Foundation, the Kavli Prizes are awarded every two years to “honor scientists for breakthroughs in astrophysics, nanoscience and neuroscience that transform our understanding of the big, the small and the complex.” The laureates in each field will share $1 million.

Understanding recognition of faces

Nancy Kanwisher, the Walter A Rosenblith Professor of Brain and Cognitive Sciences and McGovern Institute for Brain Research investigator, has been awarded the 2024 Kavli Prize in Neuroscience with Doris Tsao, professor in the Department of Molecular and Cell Biology at the University of California at Berkeley, and Winrich Freiwald, the Denise A. and Eugene W. Chinery Professor at the Rockefeller University.

Kanwisher, Tsao, and Freiwald discovered a specialized system within the brain to recognize faces. Their discoveries have provided basic principles of neural organization and made the starting point for further research on how the processing of visual information is integrated with other cognitive functions.

Kanwisher was the first to prove that a specific area in the human neocortex is dedicated to recognizing faces, now called the fusiform face area. Using functional magnetic resonance imaging, she found individual differences in the location of this area and devised an analysis technique to effectively localize specialized functional regions in the brain. This technique is now widely used and applied to domains beyond the face recognition system. 

Integrating nanomaterials for biomedical advances

Robert Langer, the David H. Koch Institute Professor, has been awarded the 2024 Kavli Prize in Nanoscience with Paul Alivisatos, president of the University of Chicago and John D. MacArthur Distinguished Service Professor in the Department of Chemistry, and Chad Mirkin, professor of chemistry at Northwestern University.

Langer, Alivisatos, and Mirkin each revolutionized the field of nanomedicine by demonstrating how engineering at the nano scale can advance biomedical research and application. Their discoveries contributed foundationally to the development of therapeutics, vaccines, bioimaging, and diagnostics.

Langer was the first to develop nanoengineered materials that enabled the controlled release, or regular flow, of drug molecules. This capability has had an immense impact for the treatment of a range of diseases, such as aggressive brain cancer, prostate cancer, and schizophrenia. His work also showed that tiny particles, containing protein antigens, can be used in vaccination, and was instrumental in the development of the delivery of messenger RNA vaccines. 

Searching for life beyond Earth

Sara Seager, the Class of 1941 Professor of Planetary Sciences in the Department of Earth, Atmospheric and Planetary Sciences and a professor in the departments of Physics and of Aeronautics and Astronautics, has been awarded the 2024 Kavli Prize in Astrophysics along with David Charbonneau, the Fred Kavli Professor of Astrophysics at Harvard University.

Seager and Charbonneau are recognized for discoveries of exoplanets and the characterization of their atmospheres. They pioneered methods for the detection of atomic species in planetary atmospheres and the measurement of their thermal infrared emission, setting the stage for finding the molecular fingerprints of atmospheres around both giant and rocky planets. Their contributions have been key to the enormous progress seen in the last 20 years in the exploration of myriad exoplanets. 

Kanwisher, Langer, and Seager bring the number of all-time MIT faculty recipients of the Kavli Prize to eight. Prior winners include Rainer Weiss in astrophysics (2016), Alan Guth in astrophysics (2014), Mildred Dresselhaus in nanoscience (2012), Ann Graybiel in neuroscience (2012), and Jane Luu in astrophysics (2012).

Physics graduate student Jeong Min (Jane) Park is among the 32 exceptional early-career scientists worldwide chosen to receive the prestigious 2024 Schmidt Science Fellows award.  

As a 2024 Schmidt Science Fellow, Park’s postdoctoral work will seek to directly detect phases that could host new particles by employing an instrument that can visualize subatomic-scale phenomena.  

With her advisor, Pablo Jarillo-Herrero, the Cecil and Ida Green Professor of Physics, Park’s research at MIT focuses on discovering novel quantum phases of matter.

“When there are many electrons in a material, their interactions can lead to collective behaviors that are not expected from individual particles, known as emergent phenomena,” explains Park. “One example is superconductivity, where interacting electrons combine together as a pair at low temperatures to conduct electricity without energy loss.”

During her PhD studies, she has investigated novel types of superconductivity by designing new materials with targeted interactions and topology. In particular, she used graphene, atomically thin two-dimensional layers of graphite, the same material as pencil lead, and turned it into a “magic” material. This so-called magic-angle twisted trilayer graphene provided an extraordinarily strong form of superconductivity that is robust under high magnetic fields. Later, she found a whole “magic family” of these materials, elucidating the key mechanisms behind superconductivity and interaction-driven phenomena. These results have provided a new platform to study emergent phenomena in two dimensions, which can lead to innovations in electronics and quantum technology.

Park says she is looking forward to her postdoctoral studies with Princeton University physics professor Ali Yazdani's lab.

“I’m excited about the idea of discovering and studying new quantum phenomena that could further the understanding of fundamental physics,” says Park. “Having explored interaction-driven phenomena through the design of new materials, I’m now aiming to broaden my perspective and expertise to address a different kind of question, by combining my background in material design with the sophisticated local-scale measurements that I will adopt during my postdoc.”

She explains that elementary particles are classified as either bosons or fermions, with contrasting behaviors upon interchanging two identical particles, referred to as exchange statistics; bosons remain unchanged, while fermions acquire a minus sign in their quantum wavefunction.

Theories predict the existence of fundamentally different particles known as non-abelian anyons, whose wavefunctions braid upon particle exchange. Such a braiding process can be used to encode and store information, potentially opening the door to fault-tolerant quantum computing in the future.

Since 2018, this prestigious postdoctoral program has sought to break down silos among scientific fields to solve the world’s biggest challenges and support future leaders in STEM.

Schmidt Science Fellows, an initiative of Schmidt Sciences, delivered in partnership with the Rhodes Trust, identifies, develops, and amplifies the next generation of science leaders, by building a community of scientists and supporters of interdisciplinary science and leveraging this network to drive sector-wide change. The 2024 fellows consist of 17 nationalities across North America, Europe, and Asia.   

Nominated candidates undergo a rigorous selection process that includes a paper-based academic review with panels of experts in their home disciplines and final interviews with panels, including senior representatives from across many scientific disciplines and different business sectors.  

John Joannopoulos, an innovator and mentor in the fields of theoretical condensed matter physics and nanophotonics, has been named the recipient of the 2024-2025 James R. Killian Jr. Faculty Achievement Award.

Joannopoulos is the Francis Wright Davis Professor of Physics and director of MIT’s Institute for Soldier Nanotechnologies. He has been a member of the MIT faculty for 50 years.

“Professor Joannopoulos’s profound and lasting impact on the field of theoretical condensed matter physics finds its roots in his pioneering work in harnessing ab initio physics to elucidate the behavior of materials at the atomic level,” states the award citation, which was announced at today’s faculty meeting by Roger White, chair of the Killian Award Selection Committee and professor of philosophy at MIT. “His seminal research in the development of photonic crystals has revolutionized understanding of light-matter interactions, laying the groundwork for transformative advancements in diverse fields ranging from telecommunications to biomedical engineering.”

The award also honors Joannopoulos’ service as a “legendary mentor to generations of students, inspiring them to achieve excellence in science while at the same time facilitating the practical benefit to society through entrepreneurship.”

The Killian Award was established in 1971 to recognize outstanding professional contributions by MIT faculty members. It is the highest honor that the faculty can give to one of its members.

“I have to tell you, it was a complete and utter surprise,” Joannopoulos told MIT News shortly after he received word of the award. “I didn’t expect it at all, and was extremely flattered, honored, and moved by it, frankly.”

Joannopoulous has spent his entire professional career at MIT. He came to the Institute in 1974, directly after receiving his PhD in physics at the University of California at Berkeley, where he also earned his bachelor’s degree. Starting out as an assistant professor in MIT’s Department of Physics, he quickly set up a research program focused on theoretical condensed matter physics.

Over the first half of his MIT career, Joannopoulos worked to elucidate the fundamental nature of the electronic, vibrational, and optical structure of crystalline and amorphous bulk solids, their surfaces, interfaces, and defects. He and his students developed numerous theoretical methods to enable tractable and accurate calculations of these complex systems.

In the 1990s, his work with microscopic material systems expanded to a new class of materials, called photonic crystals — materials that could be engineered at the micro- and nanoscale to manipulate light in ways that impart surprising and exotic optical qualities to the material as a whole.

“I saw that you could create photonic crystals with defects that can affect the properties of photons, in much the same way that defects in a semiconductor affect the properties of electrons,” Joannopoulos says. “So I started working in this area to try and explore what anomalous light phenomena can we discover using this approach?”

Among his various breakthroughs in the field was the realization of a “perfect dielectric mirror” — a multilayered optical device that reflects light from all angles as normal metallic mirrors do, and that can also be tuned to reflect and trap light at specific frequencies. He and his colleagues saw potential for the mirror to be made into a hollow fiber that could serve as a highly effective optical conduit, for use in a wide range of applications. To further advance the technology, he and his colleagues launched a startup, which has since developed the technology into a flexible, fiber-optic “surgical scalpel.”

Throughout his career, Joannopoulos has helped to launch numerous startups and photonics-based technologies.

“His ability to bridge the gap between academia and industry has not only advanced scientific knowledge but also led to the creation of dozens of new companies, thousands of jobs, and groundbreaking products that continue to benefit society to this day,” the award citation states.

In 2006, Joannopoulos accepted the position as director of MIT’s Institute for Soldier Nanotechnologies (ISN), a collaboration between MIT researchers, industry partners, and military defense experts, who seek innovations to protect and enhance soldiers’ survivability in the field. In his role as ISN head, Joannopoulos has worked across MIT, making connections and supporting new projects with researchers specializing in fields far from his own.

“I get a chance to explore and learn fascinating new things,” says Joannopoulos, who is currently overseeing projects related to hyperspectral imaging, smart and responsive fabrics, and nanodrug delivery. “I love that aspect of really getting to understand what people in other fields are doing. And they’re doing great work across many, many different fields.”

Throughout his career at MIT, Joannopoulos has been especially inspired and motivated by his students, many of whom have gone on to found companies, lead top academic and research institutions, and make significant contributions to their respective fields, including one student who was awarded the Nobel Prize in Physics in 1998.

“One’s proudest moments are the successes of one’s students, and in that regard, I’ve been extremely lucky to have had truly exceptional students over the years,” Joannopolous says.

His many contributions to academia and industry have earned Joannopoulos numerous honors and awards, including his election to both the National Academy of Sciences and the American Academy of Arts and Sciences. He is also a fellow of both the American Physical Society and the American Association for the Advancement of Science.

“The Selection Committee is delighted to have this opportunity to honor Professor John Joannopoulos: a visionary scientist, a beloved mentor, a great believer in the goodness of people, and a leader whose contributions to MIT and the broader scientific community are immeasurable,” the award citation concludes.

When Paula Hammond first arrived on MIT’s campus as a first-year student in the early 1980s, she wasn’t sure if she belonged. In fact, as she told an MIT audience yesterday, she felt like “an imposter.”

However, that feeling didn’t last long, as Hammond began to find support among her fellow students and MIT’s faculty. “Community was really important for me, to feel that I belonged, to feel that I had a place here, and I found people who were willing to embrace me and support me,” she said.

Hammond, a world-renowned chemical engineer who has spent most of her academic career at MIT, made her remarks during the 2023-24 James R. Killian Jr. Faculty Achievement Award lecture.

Established in 1971 to honor MIT’s 10th president, James Killian, the Killian Award recognizes extraordinary professional achievements by an MIT faculty member. Hammond was chosen for this year’s award “not only for her tremendous professional achievements and contributions, but also for her genuine warmth and humanity, her thoughtfulness and effective leadership, and her empathy and ethics,” according to the award citation.

“Professor Hammond is a pioneer in nanotechnology research. With a program that extends from basic science to translational research in medicine and energy, she has introduced new approaches for the design and development of complex drug delivery systems for cancer treatment and noninvasive imaging,” said Mary Fuller, chair of MIT’s faculty and a professor of literature, who presented the award. “As her colleagues, we are delighted to celebrate her career today.”

In January, Hammond began serving as MIT’s vice provost for faculty. Before that, she chaired the Department of Chemical Engineering for eight years, and she was named an Institute Professor in 2021.

A versatile technique

Hammond, who grew up in Detroit, credits her parents with instilling a love of science. Her father was one of very few Black PhDs in biochemistry at the time, while her mother earned a master’s degree in nursing from Howard University and founded the nursing school at Wayne County Community College. “That provided a huge amount of opportunity for women in the area of Detroit, including women of color,” Hammond noted.

After earning her bachelor’s degree from MIT in 1984, Hammond worked as an engineer before returning to the Institute as a graduate student, earning her PhD in 1993. After a two-year postdoc at Harvard University, she returned to join the MIT faculty in 1995.

At the heart of Hammond’s research is a technique she developed to create thin films that can essentially “shrink-wrap” nanoparticles. By tuning the chemical composition of these films, the particles can be customized to deliver drugs or nucleic acids and to target specific cells in the body, including cancer cells.

To make these films, Hammond begins by layering positively charged polymers onto a negatively charged surface. Then, more layers can be added, alternating positively and negatively charged polymers. Each of these layers may contain drugs or other useful molecules, such as DNA or RNA. Some of these films contain hundreds of layers, others just one, making them useful for a wide range of applications.

“What’s nice about the layer-by-layer process is I can choose a group of degradable polymers that are nicely biocompatible, and I can alternate them with our drug materials. This means that I can build up thin film layers that contain different drugs at different points within the film,” Hammond said. “Then, when the film degrades, it can release those drugs in reverse order. This is enabling us to create complex, multidrug films, using a simple water-based technique.”

Hammond described how these layer-by-layer films can be used to promote bone growth, in an application that could help people born with congenital bone defects or people who experience traumatic injuries.

For that use, her lab has created films with layers of two proteins. One of these, BMP-2, is a protein that interacts with adult stem cells and induces them to differentiate into bone cells, generating new bone. The second is a growth factor called VEGF, which stimulates the growth of new blood vessels that help bone to regenerate. These layers are applied to a very thin tissue scaffold that can be implanted at the injury site.

Hammond and her students designed the coating so that once implanted, it would release VEGF early, over a week or so, and continue releasing BMP-2 for up to 40 days. In a study of mice, they found that this tissue scaffold stimulated the growth of new bone that was nearly indistinguishable from natural bone.

Targeting cancer

As a member of MIT’s Koch Institute for Integrative Cancer Research, Hammond has also developed layer-by-layer coatings that can improve the performance of nanoparticles used for cancer drug delivery, such as liposomes or nanoparticles made from a polymer called PLGA.

“We have a broad range of drug carriers that we can wrap this way. I think of them like a gobstopper, where there are all those different layers of candy and they dissolve one at a time,” Hammond said.

Using this approach, Hammond has created particles that can deliver a one-two punch to cancer cells. First, the particles release a dose of a nucleic acid such as short interfering RNA (siRNA), which can turn off a cancerous gene, or microRNA, which can activate tumor suppressor genes. Then, the particles release a chemotherapy drug such as cisplatin, to which the cells are now more vulnerable.

The particles also include a negatively charged outer “stealth layer” that protects them from being broken down in the bloodstream before they can reach their targets. This outer layer can also be modified to help the particles get taken up by cancer cells, by incorporating molecules that bind to proteins that are abundant on tumor cells.

In more recent work, Hammond has begun developing nanoparticles that can target ovarian cancer and help prevent recurrence of the disease after chemotherapy. In about 70 percent of ovarian cancer patients, the first round of treatment is highly effective, but tumors recur in about 85 percent of those cases, and these new tumors are usually highly drug resistant.

By altering the type of coating applied to drug-delivering nanoparticles, Hammond has found that the particles can be designed to either get inside tumor cells or stick to their surfaces. Using particles that stick to the cells, she has designed a treatment that could help to jumpstart a patient’s immune response to any recurrent tumor cells.

“With ovarian cancer, very few immune cells exist in that space, and because they don’t have a lot of immune cells present, it’s very difficult to rev up an immune response,” she said. “However, if we can deliver a molecule to neighboring cells, those few that are present, and get them revved up, then we might be able to do something.”

To that end, she designed nanoparticles that deliver IL-12, a cytokine that stimulates nearby T cells to spring into action and begin attacking tumor cells. In a study of mice, she found that this treatment induced a long-term memory T-cell response that prevented recurrence of ovarian cancer.

Hammond closed her lecture by describing the impact that the Institute has had on her throughout her career.

“It’s been a transformative experience,” she said. “I really think of this place as special because it brings people together and enables us to do things together that we couldn’t do alone. And it is that support we get from our friends, our colleagues, and our students that really makes things possible.”

MIT faculty members Nancy Kanwisher, Robert Langer, and Sara Seager are among eight researchers worldwide to receive this year’s Kavli Prizes.

A partnership among the Norwegian Academy of Science and Letters, the Norwegian Ministry of Education and Research, and the Kavli Foundation, the Kavli Prizes are awarded every two years to “honor scientists for breakthroughs in astrophysics, nanoscience and neuroscience that transform our understanding of the big, the small and the complex.” The laureates in each field will share $1 million.

Understanding recognition of faces

Nancy Kanwisher, the Walter A Rosenblith Professor of Brain and Cognitive Sciences and McGovern Institute for Brain Research investigator, has been awarded the 2024 Kavli Prize in Neuroscience with Doris Tsao, professor in the Department of Molecular and Cell Biology at the University of California at Berkeley, and Winrich Freiwald, the Denise A. and Eugene W. Chinery Professor at the Rockefeller University.

Kanwisher, Tsao, and Freiwald discovered a specialized system within the brain to recognize faces. Their discoveries have provided basic principles of neural organization and made the starting point for further research on how the processing of visual information is integrated with other cognitive functions.

Kanwisher was the first to prove that a specific area in the human neocortex is dedicated to recognizing faces, now called the fusiform face area. Using functional magnetic resonance imaging, she found individual differences in the location of this area and devised an analysis technique to effectively localize specialized functional regions in the brain. This technique is now widely used and applied to domains beyond the face recognition system. 

Integrating nanomaterials for biomedical advances

Robert Langer, the David H. Koch Institute Professor, has been awarded the 2024 Kavli Prize in Nanoscience with Paul Alivisatos, president of the University of Chicago and John D. MacArthur Distinguished Service Professor in the Department of Chemistry, and Chad Mirkin, professor of chemistry at Northwestern University.

Langer, Alivisatos, and Mirkin each revolutionized the field of nanomedicine by demonstrating how engineering at the nano scale can advance biomedical research and application. Their discoveries contributed foundationally to the development of therapeutics, vaccines, bioimaging, and diagnostics.

Langer was the first to develop nanoengineered materials that enabled the controlled release, or regular flow, of drug molecules. This capability has had an immense impact for the treatment of a range of diseases, such as aggressive brain cancer, prostate cancer, and schizophrenia. His work also showed that tiny particles, containing protein antigens, can be used in vaccination, and was instrumental in the development of the delivery of messenger RNA vaccines. 

Searching for life beyond Earth

Sara Seager, the Class of 1941 Professor of Planetary Sciences in the Department of Earth, Atmospheric and Planetary Sciences and a professor in the departments of Physics and of Aeronautics and Astronautics, has been awarded the 2024 Kavli Prize in Astrophysics along with David Charbonneau, the Fred Kavli Professor of Astrophysics at Harvard University.

Seager and Charbonneau are recognized for discoveries of exoplanets and the characterization of their atmospheres. They pioneered methods for the detection of atomic species in planetary atmospheres and the measurement of their thermal infrared emission, setting the stage for finding the molecular fingerprints of atmospheres around both giant and rocky planets. Their contributions have been key to the enormous progress seen in the last 20 years in the exploration of myriad exoplanets. 

Kanwisher, Langer, and Seager bring the number of all-time MIT faculty recipients of the Kavli Prize to eight. Prior winners include Rainer Weiss in astrophysics (2016), Alan Guth in astrophysics (2014), Mildred Dresselhaus in nanoscience (2012), Ann Graybiel in neuroscience (2012), and Jane Luu in astrophysics (2012).

Physics graduate student Jeong Min (Jane) Park is among the 32 exceptional early-career scientists worldwide chosen to receive the prestigious 2024 Schmidt Science Fellows award.  

As a 2024 Schmidt Science Fellow, Park’s postdoctoral work will seek to directly detect phases that could host new particles by employing an instrument that can visualize subatomic-scale phenomena.  

With her advisor, Pablo Jarillo-Herrero, the Cecil and Ida Green Professor of Physics, Park’s research at MIT focuses on discovering novel quantum phases of matter.

“When there are many electrons in a material, their interactions can lead to collective behaviors that are not expected from individual particles, known as emergent phenomena,” explains Park. “One example is superconductivity, where interacting electrons combine together as a pair at low temperatures to conduct electricity without energy loss.”

During her PhD studies, she has investigated novel types of superconductivity by designing new materials with targeted interactions and topology. In particular, she used graphene, atomically thin two-dimensional layers of graphite, the same material as pencil lead, and turned it into a “magic” material. This so-called magic-angle twisted trilayer graphene provided an extraordinarily strong form of superconductivity that is robust under high magnetic fields. Later, she found a whole “magic family” of these materials, elucidating the key mechanisms behind superconductivity and interaction-driven phenomena. These results have provided a new platform to study emergent phenomena in two dimensions, which can lead to innovations in electronics and quantum technology.

Park says she is looking forward to her postdoctoral studies with Princeton University physics professor Ali Yazdani's lab.

“I’m excited about the idea of discovering and studying new quantum phenomena that could further the understanding of fundamental physics,” says Park. “Having explored interaction-driven phenomena through the design of new materials, I’m now aiming to broaden my perspective and expertise to address a different kind of question, by combining my background in material design with the sophisticated local-scale measurements that I will adopt during my postdoc.”

She explains that elementary particles are classified as either bosons or fermions, with contrasting behaviors upon interchanging two identical particles, referred to as exchange statistics; bosons remain unchanged, while fermions acquire a minus sign in their quantum wavefunction.

Theories predict the existence of fundamentally different particles known as non-abelian anyons, whose wavefunctions braid upon particle exchange. Such a braiding process can be used to encode and store information, potentially opening the door to fault-tolerant quantum computing in the future.

Since 2018, this prestigious postdoctoral program has sought to break down silos among scientific fields to solve the world’s biggest challenges and support future leaders in STEM.

Schmidt Science Fellows, an initiative of Schmidt Sciences, delivered in partnership with the Rhodes Trust, identifies, develops, and amplifies the next generation of science leaders, by building a community of scientists and supporters of interdisciplinary science and leveraging this network to drive sector-wide change. The 2024 fellows consist of 17 nationalities across North America, Europe, and Asia.   

Nominated candidates undergo a rigorous selection process that includes a paper-based academic review with panels of experts in their home disciplines and final interviews with panels, including senior representatives from across many scientific disciplines and different business sectors.  

John Joannopoulos, an innovator and mentor in the fields of theoretical condensed matter physics and nanophotonics, has been named the recipient of the 2024-2025 James R. Killian Jr. Faculty Achievement Award.

Joannopoulos is the Francis Wright Davis Professor of Physics and director of MIT’s Institute for Soldier Nanotechnologies. He has been a member of the MIT faculty for 50 years.

“Professor Joannopoulos’s profound and lasting impact on the field of theoretical condensed matter physics finds its roots in his pioneering work in harnessing ab initio physics to elucidate the behavior of materials at the atomic level,” states the award citation, which was announced at today’s faculty meeting by Roger White, chair of the Killian Award Selection Committee and professor of philosophy at MIT. “His seminal research in the development of photonic crystals has revolutionized understanding of light-matter interactions, laying the groundwork for transformative advancements in diverse fields ranging from telecommunications to biomedical engineering.”

The award also honors Joannopoulos’ service as a “legendary mentor to generations of students, inspiring them to achieve excellence in science while at the same time facilitating the practical benefit to society through entrepreneurship.”

The Killian Award was established in 1971 to recognize outstanding professional contributions by MIT faculty members. It is the highest honor that the faculty can give to one of its members.

“I have to tell you, it was a complete and utter surprise,” Joannopoulos told MIT News shortly after he received word of the award. “I didn’t expect it at all, and was extremely flattered, honored, and moved by it, frankly.”

Joannopoulous has spent his entire professional career at MIT. He came to the Institute in 1974, directly after receiving his PhD in physics at the University of California at Berkeley, where he also earned his bachelor’s degree. Starting out as an assistant professor in MIT’s Department of Physics, he quickly set up a research program focused on theoretical condensed matter physics.

Over the first half of his MIT career, Joannopoulos worked to elucidate the fundamental nature of the electronic, vibrational, and optical structure of crystalline and amorphous bulk solids, their surfaces, interfaces, and defects. He and his students developed numerous theoretical methods to enable tractable and accurate calculations of these complex systems.

In the 1990s, his work with microscopic material systems expanded to a new class of materials, called photonic crystals — materials that could be engineered at the micro- and nanoscale to manipulate light in ways that impart surprising and exotic optical qualities to the material as a whole.

“I saw that you could create photonic crystals with defects that can affect the properties of photons, in much the same way that defects in a semiconductor affect the properties of electrons,” Joannopoulos says. “So I started working in this area to try and explore what anomalous light phenomena can we discover using this approach?”

Among his various breakthroughs in the field was the realization of a “perfect dielectric mirror” — a multilayered optical device that reflects light from all angles as normal metallic mirrors do, and that can also be tuned to reflect and trap light at specific frequencies. He and his colleagues saw potential for the mirror to be made into a hollow fiber that could serve as a highly effective optical conduit, for use in a wide range of applications. To further advance the technology, he and his colleagues launched a startup, which has since developed the technology into a flexible, fiber-optic “surgical scalpel.”

Throughout his career, Joannopoulos has helped to launch numerous startups and photonics-based technologies.

“His ability to bridge the gap between academia and industry has not only advanced scientific knowledge but also led to the creation of dozens of new companies, thousands of jobs, and groundbreaking products that continue to benefit society to this day,” the award citation states.

In 2006, Joannopoulos accepted the position as director of MIT’s Institute for Soldier Nanotechnologies (ISN), a collaboration between MIT researchers, industry partners, and military defense experts, who seek innovations to protect and enhance soldiers’ survivability in the field. In his role as ISN head, Joannopoulos has worked across MIT, making connections and supporting new projects with researchers specializing in fields far from his own.

“I get a chance to explore and learn fascinating new things,” says Joannopoulos, who is currently overseeing projects related to hyperspectral imaging, smart and responsive fabrics, and nanodrug delivery. “I love that aspect of really getting to understand what people in other fields are doing. And they’re doing great work across many, many different fields.”

Throughout his career at MIT, Joannopoulos has been especially inspired and motivated by his students, many of whom have gone on to found companies, lead top academic and research institutions, and make significant contributions to their respective fields, including one student who was awarded the Nobel Prize in Physics in 1998.

“One’s proudest moments are the successes of one’s students, and in that regard, I’ve been extremely lucky to have had truly exceptional students over the years,” Joannopolous says.

His many contributions to academia and industry have earned Joannopoulos numerous honors and awards, including his election to both the National Academy of Sciences and the American Academy of Arts and Sciences. He is also a fellow of both the American Physical Society and the American Association for the Advancement of Science.

“The Selection Committee is delighted to have this opportunity to honor Professor John Joannopoulos: a visionary scientist, a beloved mentor, a great believer in the goodness of people, and a leader whose contributions to MIT and the broader scientific community are immeasurable,” the award citation concludes.

When Paula Hammond first arrived on MIT’s campus as a first-year student in the early 1980s, she wasn’t sure if she belonged. In fact, as she told an MIT audience yesterday, she felt like “an imposter.”

However, that feeling didn’t last long, as Hammond began to find support among her fellow students and MIT’s faculty. “Community was really important for me, to feel that I belonged, to feel that I had a place here, and I found people who were willing to embrace me and support me,” she said.

Hammond, a world-renowned chemical engineer who has spent most of her academic career at MIT, made her remarks during the 2023-24 James R. Killian Jr. Faculty Achievement Award lecture.

Established in 1971 to honor MIT’s 10th president, James Killian, the Killian Award recognizes extraordinary professional achievements by an MIT faculty member. Hammond was chosen for this year’s award “not only for her tremendous professional achievements and contributions, but also for her genuine warmth and humanity, her thoughtfulness and effective leadership, and her empathy and ethics,” according to the award citation.

“Professor Hammond is a pioneer in nanotechnology research. With a program that extends from basic science to translational research in medicine and energy, she has introduced new approaches for the design and development of complex drug delivery systems for cancer treatment and noninvasive imaging,” said Mary Fuller, chair of MIT’s faculty and a professor of literature, who presented the award. “As her colleagues, we are delighted to celebrate her career today.”

In January, Hammond began serving as MIT’s vice provost for faculty. Before that, she chaired the Department of Chemical Engineering for eight years, and she was named an Institute Professor in 2021.

A versatile technique

Hammond, who grew up in Detroit, credits her parents with instilling a love of science. Her father was one of very few Black PhDs in biochemistry at the time, while her mother earned a master’s degree in nursing from Howard University and founded the nursing school at Wayne County Community College. “That provided a huge amount of opportunity for women in the area of Detroit, including women of color,” Hammond noted.

After earning her bachelor’s degree from MIT in 1984, Hammond worked as an engineer before returning to the Institute as a graduate student, earning her PhD in 1993. After a two-year postdoc at Harvard University, she returned to join the MIT faculty in 1995.

At the heart of Hammond’s research is a technique she developed to create thin films that can essentially “shrink-wrap” nanoparticles. By tuning the chemical composition of these films, the particles can be customized to deliver drugs or nucleic acids and to target specific cells in the body, including cancer cells.

To make these films, Hammond begins by layering positively charged polymers onto a negatively charged surface. Then, more layers can be added, alternating positively and negatively charged polymers. Each of these layers may contain drugs or other useful molecules, such as DNA or RNA. Some of these films contain hundreds of layers, others just one, making them useful for a wide range of applications.

“What’s nice about the layer-by-layer process is I can choose a group of degradable polymers that are nicely biocompatible, and I can alternate them with our drug materials. This means that I can build up thin film layers that contain different drugs at different points within the film,” Hammond said. “Then, when the film degrades, it can release those drugs in reverse order. This is enabling us to create complex, multidrug films, using a simple water-based technique.”

Hammond described how these layer-by-layer films can be used to promote bone growth, in an application that could help people born with congenital bone defects or people who experience traumatic injuries.

For that use, her lab has created films with layers of two proteins. One of these, BMP-2, is a protein that interacts with adult stem cells and induces them to differentiate into bone cells, generating new bone. The second is a growth factor called VEGF, which stimulates the growth of new blood vessels that help bone to regenerate. These layers are applied to a very thin tissue scaffold that can be implanted at the injury site.

Hammond and her students designed the coating so that once implanted, it would release VEGF early, over a week or so, and continue releasing BMP-2 for up to 40 days. In a study of mice, they found that this tissue scaffold stimulated the growth of new bone that was nearly indistinguishable from natural bone.

Targeting cancer

As a member of MIT’s Koch Institute for Integrative Cancer Research, Hammond has also developed layer-by-layer coatings that can improve the performance of nanoparticles used for cancer drug delivery, such as liposomes or nanoparticles made from a polymer called PLGA.

“We have a broad range of drug carriers that we can wrap this way. I think of them like a gobstopper, where there are all those different layers of candy and they dissolve one at a time,” Hammond said.

Using this approach, Hammond has created particles that can deliver a one-two punch to cancer cells. First, the particles release a dose of a nucleic acid such as short interfering RNA (siRNA), which can turn off a cancerous gene, or microRNA, which can activate tumor suppressor genes. Then, the particles release a chemotherapy drug such as cisplatin, to which the cells are now more vulnerable.

The particles also include a negatively charged outer “stealth layer” that protects them from being broken down in the bloodstream before they can reach their targets. This outer layer can also be modified to help the particles get taken up by cancer cells, by incorporating molecules that bind to proteins that are abundant on tumor cells.

In more recent work, Hammond has begun developing nanoparticles that can target ovarian cancer and help prevent recurrence of the disease after chemotherapy. In about 70 percent of ovarian cancer patients, the first round of treatment is highly effective, but tumors recur in about 85 percent of those cases, and these new tumors are usually highly drug resistant.

By altering the type of coating applied to drug-delivering nanoparticles, Hammond has found that the particles can be designed to either get inside tumor cells or stick to their surfaces. Using particles that stick to the cells, she has designed a treatment that could help to jumpstart a patient’s immune response to any recurrent tumor cells.

“With ovarian cancer, very few immune cells exist in that space, and because they don’t have a lot of immune cells present, it’s very difficult to rev up an immune response,” she said. “However, if we can deliver a molecule to neighboring cells, those few that are present, and get them revved up, then we might be able to do something.”

To that end, she designed nanoparticles that deliver IL-12, a cytokine that stimulates nearby T cells to spring into action and begin attacking tumor cells. In a study of mice, she found that this treatment induced a long-term memory T-cell response that prevented recurrence of ovarian cancer.

Hammond closed her lecture by describing the impact that the Institute has had on her throughout her career.

“It’s been a transformative experience,” she said. “I really think of this place as special because it brings people together and enables us to do things together that we couldn’t do alone. And it is that support we get from our friends, our colleagues, and our students that really makes things possible.”

Physics graduate student Jeong Min (Jane) Park is among the 32 exceptional early-career scientists worldwide chosen to receive the prestigious 2024 Schmidt Science Fellows award.  

As a 2024 Schmidt Science Fellow, Park’s postdoctoral work will seek to directly detect phases that could host new particles by employing an instrument that can visualize subatomic-scale phenomena.  

With her advisor, Pablo Jarillo-Herrero, the Cecil and Ida Green Professor of Physics, Park’s research at MIT focuses on discovering novel quantum phases of matter.

“When there are many electrons in a material, their interactions can lead to collective behaviors that are not expected from individual particles, known as emergent phenomena,” explains Park. “One example is superconductivity, where interacting electrons combine together as a pair at low temperatures to conduct electricity without energy loss.”

During her PhD studies, she has investigated novel types of superconductivity by designing new materials with targeted interactions and topology. In particular, she used graphene, atomically thin two-dimensional layers of graphite, the same material as pencil lead, and turned it into a “magic” material. This so-called magic-angle twisted trilayer graphene provided an extraordinarily strong form of superconductivity that is robust under high magnetic fields. Later, she found a whole “magic family” of these materials, elucidating the key mechanisms behind superconductivity and interaction-driven phenomena. These results have provided a new platform to study emergent phenomena in two dimensions, which can lead to innovations in electronics and quantum technology.

Park says she is looking forward to her postdoctoral studies with Princeton University physics professor Ali Yazdani's lab.

“I’m excited about the idea of discovering and studying new quantum phenomena that could further the understanding of fundamental physics,” says Park. “Having explored interaction-driven phenomena through the design of new materials, I’m now aiming to broaden my perspective and expertise to address a different kind of question, by combining my background in material design with the sophisticated local-scale measurements that I will adopt during my postdoc.”

She explains that elementary particles are classified as either bosons or fermions, with contrasting behaviors upon interchanging two identical particles, referred to as exchange statistics; bosons remain unchanged, while fermions acquire a minus sign in their quantum wavefunction.

Theories predict the existence of fundamentally different particles known as non-abelian anyons, whose wavefunctions braid upon particle exchange. Such a braiding process can be used to encode and store information, potentially opening the door to fault-tolerant quantum computing in the future.

Since 2018, this prestigious postdoctoral program has sought to break down silos among scientific fields to solve the world’s biggest challenges and support future leaders in STEM.

Schmidt Science Fellows, an initiative of Schmidt Sciences, delivered in partnership with the Rhodes Trust, identifies, develops, and amplifies the next generation of science leaders, by building a community of scientists and supporters of interdisciplinary science and leveraging this network to drive sector-wide change. The 2024 fellows consist of 17 nationalities across North America, Europe, and Asia.   

Nominated candidates undergo a rigorous selection process that includes a paper-based academic review with panels of experts in their home disciplines and final interviews with panels, including senior representatives from across many scientific disciplines and different business sectors.  

John Joannopoulos, an innovator and mentor in the fields of theoretical condensed matter physics and nanophotonics, has been named the recipient of the 2024-2025 James R. Killian Jr. Faculty Achievement Award.

Joannopoulos is the Francis Wright Davis Professor of Physics and director of MIT’s Institute for Soldier Nanotechnologies. He has been a member of the MIT faculty for 50 years.

“Professor Joannopoulos’s profound and lasting impact on the field of theoretical condensed matter physics finds its roots in his pioneering work in harnessing ab initio physics to elucidate the behavior of materials at the atomic level,” states the award citation, which was announced at today’s faculty meeting by Roger White, chair of the Killian Award Selection Committee and professor of philosophy at MIT. “His seminal research in the development of photonic crystals has revolutionized understanding of light-matter interactions, laying the groundwork for transformative advancements in diverse fields ranging from telecommunications to biomedical engineering.”

The award also honors Joannopoulos’ service as a “legendary mentor to generations of students, inspiring them to achieve excellence in science while at the same time facilitating the practical benefit to society through entrepreneurship.”

The Killian Award was established in 1971 to recognize outstanding professional contributions by MIT faculty members. It is the highest honor that the faculty can give to one of its members.

“I have to tell you, it was a complete and utter surprise,” Joannopoulos told MIT News shortly after he received word of the award. “I didn’t expect it at all, and was extremely flattered, honored, and moved by it, frankly.”

Joannopoulous has spent his entire professional career at MIT. He came to the Institute in 1974, directly after receiving his PhD in physics at the University of California at Berkeley, where he also earned his bachelor’s degree. Starting out as an assistant professor in MIT’s Department of Physics, he quickly set up a research program focused on theoretical condensed matter physics.

Over the first half of his MIT career, Joannopoulos worked to elucidate the fundamental nature of the electronic, vibrational, and optical structure of crystalline and amorphous bulk solids, their surfaces, interfaces, and defects. He and his students developed numerous theoretical methods to enable tractable and accurate calculations of these complex systems.

In the 1990s, his work with microscopic material systems expanded to a new class of materials, called photonic crystals — materials that could be engineered at the micro- and nanoscale to manipulate light in ways that impart surprising and exotic optical qualities to the material as a whole.

“I saw that you could create photonic crystals with defects that can affect the properties of photons, in much the same way that defects in a semiconductor affect the properties of electrons,” Joannopoulos says. “So I started working in this area to try and explore what anomalous light phenomena can we discover using this approach?”

Among his various breakthroughs in the field was the realization of a “perfect dielectric mirror” — a multilayered optical device that reflects light from all angles as normal metallic mirrors do, and that can also be tuned to reflect and trap light at specific frequencies. He and his colleagues saw potential for the mirror to be made into a hollow fiber that could serve as a highly effective optical conduit, for use in a wide range of applications. To further advance the technology, he and his colleagues launched a startup, which has since developed the technology into a flexible, fiber-optic “surgical scalpel.”

Throughout his career, Joannopoulos has helped to launch numerous startups and photonics-based technologies.

“His ability to bridge the gap between academia and industry has not only advanced scientific knowledge but also led to the creation of dozens of new companies, thousands of jobs, and groundbreaking products that continue to benefit society to this day,” the award citation states.

In 2006, Joannopoulos accepted the position as director of MIT’s Institute for Soldier Nanotechnologies (ISN), a collaboration between MIT researchers, industry partners, and military defense experts, who seek innovations to protect and enhance soldiers’ survivability in the field. In his role as ISN head, Joannopoulos has worked across MIT, making connections and supporting new projects with researchers specializing in fields far from his own.

“I get a chance to explore and learn fascinating new things,” says Joannopoulos, who is currently overseeing projects related to hyperspectral imaging, smart and responsive fabrics, and nanodrug delivery. “I love that aspect of really getting to understand what people in other fields are doing. And they’re doing great work across many, many different fields.”

Throughout his career at MIT, Joannopoulos has been especially inspired and motivated by his students, many of whom have gone on to found companies, lead top academic and research institutions, and make significant contributions to their respective fields, including one student who was awarded the Nobel Prize in Physics in 1998.

“One’s proudest moments are the successes of one’s students, and in that regard, I’ve been extremely lucky to have had truly exceptional students over the years,” Joannopolous says.

His many contributions to academia and industry have earned Joannopoulos numerous honors and awards, including his election to both the National Academy of Sciences and the American Academy of Arts and Sciences. He is also a fellow of both the American Physical Society and the American Association for the Advancement of Science.

“The Selection Committee is delighted to have this opportunity to honor Professor John Joannopoulos: a visionary scientist, a beloved mentor, a great believer in the goodness of people, and a leader whose contributions to MIT and the broader scientific community are immeasurable,” the award citation concludes.

When Paula Hammond first arrived on MIT’s campus as a first-year student in the early 1980s, she wasn’t sure if she belonged. In fact, as she told an MIT audience yesterday, she felt like “an imposter.”

However, that feeling didn’t last long, as Hammond began to find support among her fellow students and MIT’s faculty. “Community was really important for me, to feel that I belonged, to feel that I had a place here, and I found people who were willing to embrace me and support me,” she said.

Hammond, a world-renowned chemical engineer who has spent most of her academic career at MIT, made her remarks during the 2023-24 James R. Killian Jr. Faculty Achievement Award lecture.

Established in 1971 to honor MIT’s 10th president, James Killian, the Killian Award recognizes extraordinary professional achievements by an MIT faculty member. Hammond was chosen for this year’s award “not only for her tremendous professional achievements and contributions, but also for her genuine warmth and humanity, her thoughtfulness and effective leadership, and her empathy and ethics,” according to the award citation.

“Professor Hammond is a pioneer in nanotechnology research. With a program that extends from basic science to translational research in medicine and energy, she has introduced new approaches for the design and development of complex drug delivery systems for cancer treatment and noninvasive imaging,” said Mary Fuller, chair of MIT’s faculty and a professor of literature, who presented the award. “As her colleagues, we are delighted to celebrate her career today.”

In January, Hammond began serving as MIT’s vice provost for faculty. Before that, she chaired the Department of Chemical Engineering for eight years, and she was named an Institute Professor in 2021.

A versatile technique

Hammond, who grew up in Detroit, credits her parents with instilling a love of science. Her father was one of very few Black PhDs in biochemistry at the time, while her mother earned a master’s degree in nursing from Howard University and founded the nursing school at Wayne County Community College. “That provided a huge amount of opportunity for women in the area of Detroit, including women of color,” Hammond noted.

After earning her bachelor’s degree from MIT in 1984, Hammond worked as an engineer before returning to the Institute as a graduate student, earning her PhD in 1993. After a two-year postdoc at Harvard University, she returned to join the MIT faculty in 1995.

At the heart of Hammond’s research is a technique she developed to create thin films that can essentially “shrink-wrap” nanoparticles. By tuning the chemical composition of these films, the particles can be customized to deliver drugs or nucleic acids and to target specific cells in the body, including cancer cells.

To make these films, Hammond begins by layering positively charged polymers onto a negatively charged surface. Then, more layers can be added, alternating positively and negatively charged polymers. Each of these layers may contain drugs or other useful molecules, such as DNA or RNA. Some of these films contain hundreds of layers, others just one, making them useful for a wide range of applications.

“What’s nice about the layer-by-layer process is I can choose a group of degradable polymers that are nicely biocompatible, and I can alternate them with our drug materials. This means that I can build up thin film layers that contain different drugs at different points within the film,” Hammond said. “Then, when the film degrades, it can release those drugs in reverse order. This is enabling us to create complex, multidrug films, using a simple water-based technique.”

Hammond described how these layer-by-layer films can be used to promote bone growth, in an application that could help people born with congenital bone defects or people who experience traumatic injuries.

For that use, her lab has created films with layers of two proteins. One of these, BMP-2, is a protein that interacts with adult stem cells and induces them to differentiate into bone cells, generating new bone. The second is a growth factor called VEGF, which stimulates the growth of new blood vessels that help bone to regenerate. These layers are applied to a very thin tissue scaffold that can be implanted at the injury site.

Hammond and her students designed the coating so that once implanted, it would release VEGF early, over a week or so, and continue releasing BMP-2 for up to 40 days. In a study of mice, they found that this tissue scaffold stimulated the growth of new bone that was nearly indistinguishable from natural bone.

Targeting cancer

As a member of MIT’s Koch Institute for Integrative Cancer Research, Hammond has also developed layer-by-layer coatings that can improve the performance of nanoparticles used for cancer drug delivery, such as liposomes or nanoparticles made from a polymer called PLGA.

“We have a broad range of drug carriers that we can wrap this way. I think of them like a gobstopper, where there are all those different layers of candy and they dissolve one at a time,” Hammond said.

Using this approach, Hammond has created particles that can deliver a one-two punch to cancer cells. First, the particles release a dose of a nucleic acid such as short interfering RNA (siRNA), which can turn off a cancerous gene, or microRNA, which can activate tumor suppressor genes. Then, the particles release a chemotherapy drug such as cisplatin, to which the cells are now more vulnerable.

The particles also include a negatively charged outer “stealth layer” that protects them from being broken down in the bloodstream before they can reach their targets. This outer layer can also be modified to help the particles get taken up by cancer cells, by incorporating molecules that bind to proteins that are abundant on tumor cells.

In more recent work, Hammond has begun developing nanoparticles that can target ovarian cancer and help prevent recurrence of the disease after chemotherapy. In about 70 percent of ovarian cancer patients, the first round of treatment is highly effective, but tumors recur in about 85 percent of those cases, and these new tumors are usually highly drug resistant.

By altering the type of coating applied to drug-delivering nanoparticles, Hammond has found that the particles can be designed to either get inside tumor cells or stick to their surfaces. Using particles that stick to the cells, she has designed a treatment that could help to jumpstart a patient’s immune response to any recurrent tumor cells.

“With ovarian cancer, very few immune cells exist in that space, and because they don’t have a lot of immune cells present, it’s very difficult to rev up an immune response,” she said. “However, if we can deliver a molecule to neighboring cells, those few that are present, and get them revved up, then we might be able to do something.”

To that end, she designed nanoparticles that deliver IL-12, a cytokine that stimulates nearby T cells to spring into action and begin attacking tumor cells. In a study of mice, she found that this treatment induced a long-term memory T-cell response that prevented recurrence of ovarian cancer.

Hammond closed her lecture by describing the impact that the Institute has had on her throughout her career.

“It’s been a transformative experience,” she said. “I really think of this place as special because it brings people together and enables us to do things together that we couldn’t do alone. And it is that support we get from our friends, our colleagues, and our students that really makes things possible.”

Physics graduate student Jeong Min (Jane) Park is among the 32 exceptional early-career scientists worldwide chosen to receive the prestigious 2024 Schmidt Science Fellows award.  

As a 2024 Schmidt Science Fellow, Park’s postdoctoral work will seek to directly detect phases that could host new particles by employing an instrument that can visualize subatomic-scale phenomena.  

With her advisor, Pablo Jarillo-Herrero, the Cecil and Ida Green Professor of Physics, Park’s research at MIT focuses on discovering novel quantum phases of matter.

“When there are many electrons in a material, their interactions can lead to collective behaviors that are not expected from individual particles, known as emergent phenomena,” explains Park. “One example is superconductivity, where interacting electrons combine together as a pair at low temperatures to conduct electricity without energy loss.”

During her PhD studies, she has investigated novel types of superconductivity by designing new materials with targeted interactions and topology. In particular, she used graphene, atomically thin two-dimensional layers of graphite, the same material as pencil lead, and turned it into a “magic” material. This so-called magic-angle twisted trilayer graphene provided an extraordinarily strong form of superconductivity that is robust under high magnetic fields. Later, she found a whole “magic family” of these materials, elucidating the key mechanisms behind superconductivity and interaction-driven phenomena. These results have provided a new platform to study emergent phenomena in two dimensions, which can lead to innovations in electronics and quantum technology.

Park says she is looking forward to her postdoctoral studies with Princeton University physics professor Ali Yazdani's lab.

“I’m excited about the idea of discovering and studying new quantum phenomena that could further the understanding of fundamental physics,” says Park. “Having explored interaction-driven phenomena through the design of new materials, I’m now aiming to broaden my perspective and expertise to address a different kind of question, by combining my background in material design with the sophisticated local-scale measurements that I will adopt during my postdoc.”

She explains that elementary particles are classified as either bosons or fermions, with contrasting behaviors upon interchanging two identical particles, referred to as exchange statistics; bosons remain unchanged, while fermions acquire a minus sign in their quantum wavefunction.

Theories predict the existence of fundamentally different particles known as non-abelian anyons, whose wavefunctions braid upon particle exchange. Such a braiding process can be used to encode and store information, potentially opening the door to fault-tolerant quantum computing in the future.

Since 2018, this prestigious postdoctoral program has sought to break down silos among scientific fields to solve the world’s biggest challenges and support future leaders in STEM.

Schmidt Science Fellows, an initiative of Schmidt Sciences, delivered in partnership with the Rhodes Trust, identifies, develops, and amplifies the next generation of science leaders, by building a community of scientists and supporters of interdisciplinary science and leveraging this network to drive sector-wide change. The 2024 fellows consist of 17 nationalities across North America, Europe, and Asia.   

Nominated candidates undergo a rigorous selection process that includes a paper-based academic review with panels of experts in their home disciplines and final interviews with panels, including senior representatives from across many scientific disciplines and different business sectors.  

John Joannopoulos, an innovator and mentor in the fields of theoretical condensed matter physics and nanophotonics, has been named the recipient of the 2024-2025 James R. Killian Jr. Faculty Achievement Award.

Joannopoulos is the Francis Wright Davis Professor of Physics and director of MIT’s Institute for Soldier Nanotechnologies. He has been a member of the MIT faculty for 50 years.

“Professor Joannopoulos’s profound and lasting impact on the field of theoretical condensed matter physics finds its roots in his pioneering work in harnessing ab initio physics to elucidate the behavior of materials at the atomic level,” states the award citation, which was announced at today’s faculty meeting by Roger White, chair of the Killian Award Selection Committee and professor of philosophy at MIT. “His seminal research in the development of photonic crystals has revolutionized understanding of light-matter interactions, laying the groundwork for transformative advancements in diverse fields ranging from telecommunications to biomedical engineering.”

The award also honors Joannopoulos’ service as a “legendary mentor to generations of students, inspiring them to achieve excellence in science while at the same time facilitating the practical benefit to society through entrepreneurship.”

The Killian Award was established in 1971 to recognize outstanding professional contributions by MIT faculty members. It is the highest honor that the faculty can give to one of its members.

“I have to tell you, it was a complete and utter surprise,” Joannopoulos told MIT News shortly after he received word of the award. “I didn’t expect it at all, and was extremely flattered, honored, and moved by it, frankly.”

Joannopoulous has spent his entire professional career at MIT. He came to the Institute in 1974, directly after receiving his PhD in physics at the University of California at Berkeley, where he also earned his bachelor’s degree. Starting out as an assistant professor in MIT’s Department of Physics, he quickly set up a research program focused on theoretical condensed matter physics.

Over the first half of his MIT career, Joannopoulos worked to elucidate the fundamental nature of the electronic, vibrational, and optical structure of crystalline and amorphous bulk solids, their surfaces, interfaces, and defects. He and his students developed numerous theoretical methods to enable tractable and accurate calculations of these complex systems.

In the 1990s, his work with microscopic material systems expanded to a new class of materials, called photonic crystals — materials that could be engineered at the micro- and nanoscale to manipulate light in ways that impart surprising and exotic optical qualities to the material as a whole.

“I saw that you could create photonic crystals with defects that can affect the properties of photons, in much the same way that defects in a semiconductor affect the properties of electrons,” Joannopoulos says. “So I started working in this area to try and explore what anomalous light phenomena can we discover using this approach?”

Among his various breakthroughs in the field was the realization of a “perfect dielectric mirror” — a multilayered optical device that reflects light from all angles as normal metallic mirrors do, and that can also be tuned to reflect and trap light at specific frequencies. He and his colleagues saw potential for the mirror to be made into a hollow fiber that could serve as a highly effective optical conduit, for use in a wide range of applications. To further advance the technology, he and his colleagues launched a startup, which has since developed the technology into a flexible, fiber-optic “surgical scalpel.”

Throughout his career, Joannopoulos has helped to launch numerous startups and photonics-based technologies.

“His ability to bridge the gap between academia and industry has not only advanced scientific knowledge but also led to the creation of dozens of new companies, thousands of jobs, and groundbreaking products that continue to benefit society to this day,” the award citation states.

In 2006, Joannopoulos accepted the position as director of MIT’s Institute for Soldier Nanotechnologies (ISN), a collaboration between MIT researchers, industry partners, and military defense experts, who seek innovations to protect and enhance soldiers’ survivability in the field. In his role as ISN head, Joannopoulos has worked across MIT, making connections and supporting new projects with researchers specializing in fields far from his own.

“I get a chance to explore and learn fascinating new things,” says Joannopoulos, who is currently overseeing projects related to hyperspectral imaging, smart and responsive fabrics, and nanodrug delivery. “I love that aspect of really getting to understand what people in other fields are doing. And they’re doing great work across many, many different fields.”

Throughout his career at MIT, Joannopoulos has been especially inspired and motivated by his students, many of whom have gone on to found companies, lead top academic and research institutions, and make significant contributions to their respective fields, including one student who was awarded the Nobel Prize in Physics in 1998.

“One’s proudest moments are the successes of one’s students, and in that regard, I’ve been extremely lucky to have had truly exceptional students over the years,” Joannopolous says.

His many contributions to academia and industry have earned Joannopoulos numerous honors and awards, including his election to both the National Academy of Sciences and the American Academy of Arts and Sciences. He is also a fellow of both the American Physical Society and the American Association for the Advancement of Science.

“The Selection Committee is delighted to have this opportunity to honor Professor John Joannopoulos: a visionary scientist, a beloved mentor, a great believer in the goodness of people, and a leader whose contributions to MIT and the broader scientific community are immeasurable,” the award citation concludes.

When Paula Hammond first arrived on MIT’s campus as a first-year student in the early 1980s, she wasn’t sure if she belonged. In fact, as she told an MIT audience yesterday, she felt like “an imposter.”

However, that feeling didn’t last long, as Hammond began to find support among her fellow students and MIT’s faculty. “Community was really important for me, to feel that I belonged, to feel that I had a place here, and I found people who were willing to embrace me and support me,” she said.

Hammond, a world-renowned chemical engineer who has spent most of her academic career at MIT, made her remarks during the 2023-24 James R. Killian Jr. Faculty Achievement Award lecture.

Established in 1971 to honor MIT’s 10th president, James Killian, the Killian Award recognizes extraordinary professional achievements by an MIT faculty member. Hammond was chosen for this year’s award “not only for her tremendous professional achievements and contributions, but also for her genuine warmth and humanity, her thoughtfulness and effective leadership, and her empathy and ethics,” according to the award citation.

“Professor Hammond is a pioneer in nanotechnology research. With a program that extends from basic science to translational research in medicine and energy, she has introduced new approaches for the design and development of complex drug delivery systems for cancer treatment and noninvasive imaging,” said Mary Fuller, chair of MIT’s faculty and a professor of literature, who presented the award. “As her colleagues, we are delighted to celebrate her career today.”

In January, Hammond began serving as MIT’s vice provost for faculty. Before that, she chaired the Department of Chemical Engineering for eight years, and she was named an Institute Professor in 2021.

A versatile technique

Hammond, who grew up in Detroit, credits her parents with instilling a love of science. Her father was one of very few Black PhDs in biochemistry at the time, while her mother earned a master’s degree in nursing from Howard University and founded the nursing school at Wayne County Community College. “That provided a huge amount of opportunity for women in the area of Detroit, including women of color,” Hammond noted.

After earning her bachelor’s degree from MIT in 1984, Hammond worked as an engineer before returning to the Institute as a graduate student, earning her PhD in 1993. After a two-year postdoc at Harvard University, she returned to join the MIT faculty in 1995.

At the heart of Hammond’s research is a technique she developed to create thin films that can essentially “shrink-wrap” nanoparticles. By tuning the chemical composition of these films, the particles can be customized to deliver drugs or nucleic acids and to target specific cells in the body, including cancer cells.

To make these films, Hammond begins by layering positively charged polymers onto a negatively charged surface. Then, more layers can be added, alternating positively and negatively charged polymers. Each of these layers may contain drugs or other useful molecules, such as DNA or RNA. Some of these films contain hundreds of layers, others just one, making them useful for a wide range of applications.

“What’s nice about the layer-by-layer process is I can choose a group of degradable polymers that are nicely biocompatible, and I can alternate them with our drug materials. This means that I can build up thin film layers that contain different drugs at different points within the film,” Hammond said. “Then, when the film degrades, it can release those drugs in reverse order. This is enabling us to create complex, multidrug films, using a simple water-based technique.”

Hammond described how these layer-by-layer films can be used to promote bone growth, in an application that could help people born with congenital bone defects or people who experience traumatic injuries.

For that use, her lab has created films with layers of two proteins. One of these, BMP-2, is a protein that interacts with adult stem cells and induces them to differentiate into bone cells, generating new bone. The second is a growth factor called VEGF, which stimulates the growth of new blood vessels that help bone to regenerate. These layers are applied to a very thin tissue scaffold that can be implanted at the injury site.

Hammond and her students designed the coating so that once implanted, it would release VEGF early, over a week or so, and continue releasing BMP-2 for up to 40 days. In a study of mice, they found that this tissue scaffold stimulated the growth of new bone that was nearly indistinguishable from natural bone.

Targeting cancer

As a member of MIT’s Koch Institute for Integrative Cancer Research, Hammond has also developed layer-by-layer coatings that can improve the performance of nanoparticles used for cancer drug delivery, such as liposomes or nanoparticles made from a polymer called PLGA.

“We have a broad range of drug carriers that we can wrap this way. I think of them like a gobstopper, where there are all those different layers of candy and they dissolve one at a time,” Hammond said.

Using this approach, Hammond has created particles that can deliver a one-two punch to cancer cells. First, the particles release a dose of a nucleic acid such as short interfering RNA (siRNA), which can turn off a cancerous gene, or microRNA, which can activate tumor suppressor genes. Then, the particles release a chemotherapy drug such as cisplatin, to which the cells are now more vulnerable.

The particles also include a negatively charged outer “stealth layer” that protects them from being broken down in the bloodstream before they can reach their targets. This outer layer can also be modified to help the particles get taken up by cancer cells, by incorporating molecules that bind to proteins that are abundant on tumor cells.

In more recent work, Hammond has begun developing nanoparticles that can target ovarian cancer and help prevent recurrence of the disease after chemotherapy. In about 70 percent of ovarian cancer patients, the first round of treatment is highly effective, but tumors recur in about 85 percent of those cases, and these new tumors are usually highly drug resistant.

By altering the type of coating applied to drug-delivering nanoparticles, Hammond has found that the particles can be designed to either get inside tumor cells or stick to their surfaces. Using particles that stick to the cells, she has designed a treatment that could help to jumpstart a patient’s immune response to any recurrent tumor cells.

“With ovarian cancer, very few immune cells exist in that space, and because they don’t have a lot of immune cells present, it’s very difficult to rev up an immune response,” she said. “However, if we can deliver a molecule to neighboring cells, those few that are present, and get them revved up, then we might be able to do something.”

To that end, she designed nanoparticles that deliver IL-12, a cytokine that stimulates nearby T cells to spring into action and begin attacking tumor cells. In a study of mice, she found that this treatment induced a long-term memory T-cell response that prevented recurrence of ovarian cancer.

Hammond closed her lecture by describing the impact that the Institute has had on her throughout her career.

“It’s been a transformative experience,” she said. “I really think of this place as special because it brings people together and enables us to do things together that we couldn’t do alone. And it is that support we get from our friends, our colleagues, and our students that really makes things possible.”

Physics graduate student Jeong Min (Jane) Park is among the 32 exceptional early-career scientists worldwide chosen to receive the prestigious 2024 Schmidt Science Fellows award.  

As a 2024 Schmidt Science Fellow, Park’s postdoctoral work will seek to directly detect phases that could host new particles by employing an instrument that can visualize subatomic-scale phenomena.  

With her advisor, Pablo Jarillo-Herrero, the Cecil and Ida Green Professor of Physics, Park’s research at MIT focuses on discovering novel quantum phases of matter.

“When there are many electrons in a material, their interactions can lead to collective behaviors that are not expected from individual particles, known as emergent phenomena,” explains Park. “One example is superconductivity, where interacting electrons combine together as a pair at low temperatures to conduct electricity without energy loss.”

During her PhD studies, she has investigated novel types of superconductivity by designing new materials with targeted interactions and topology. In particular, she used graphene, atomically thin two-dimensional layers of graphite, the same material as pencil lead, and turned it into a “magic” material. This so-called magic-angle twisted trilayer graphene provided an extraordinarily strong form of superconductivity that is robust under high magnetic fields. Later, she found a whole “magic family” of these materials, elucidating the key mechanisms behind superconductivity and interaction-driven phenomena. These results have provided a new platform to study emergent phenomena in two dimensions, which can lead to innovations in electronics and quantum technology.

Park says she is looking forward to her postdoctoral studies with Princeton University physics professor Ali Yazdani's lab.

“I’m excited about the idea of discovering and studying new quantum phenomena that could further the understanding of fundamental physics,” says Park. “Having explored interaction-driven phenomena through the design of new materials, I’m now aiming to broaden my perspective and expertise to address a different kind of question, by combining my background in material design with the sophisticated local-scale measurements that I will adopt during my postdoc.”

She explains that elementary particles are classified as either bosons or fermions, with contrasting behaviors upon interchanging two identical particles, referred to as exchange statistics; bosons remain unchanged, while fermions acquire a minus sign in their quantum wavefunction.

Theories predict the existence of fundamentally different particles known as non-abelian anyons, whose wavefunctions braid upon particle exchange. Such a braiding process can be used to encode and store information, potentially opening the door to fault-tolerant quantum computing in the future.

Since 2018, this prestigious postdoctoral program has sought to break down silos among scientific fields to solve the world’s biggest challenges and support future leaders in STEM.

Schmidt Science Fellows, an initiative of Schmidt Sciences, delivered in partnership with the Rhodes Trust, identifies, develops, and amplifies the next generation of science leaders, by building a community of scientists and supporters of interdisciplinary science and leveraging this network to drive sector-wide change. The 2024 fellows consist of 17 nationalities across North America, Europe, and Asia.   

Nominated candidates undergo a rigorous selection process that includes a paper-based academic review with panels of experts in their home disciplines and final interviews with panels, including senior representatives from across many scientific disciplines and different business sectors.  

John Joannopoulos, an innovator and mentor in the fields of theoretical condensed matter physics and nanophotonics, has been named the recipient of the 2024-2025 James R. Killian Jr. Faculty Achievement Award.

Joannopoulos is the Francis Wright Davis Professor of Physics and director of MIT’s Institute for Soldier Nanotechnologies. He has been a member of the MIT faculty for 50 years.

“Professor Joannopoulos’s profound and lasting impact on the field of theoretical condensed matter physics finds its roots in his pioneering work in harnessing ab initio physics to elucidate the behavior of materials at the atomic level,” states the award citation, which was announced at today’s faculty meeting by Roger White, chair of the Killian Award Selection Committee and professor of philosophy at MIT. “His seminal research in the development of photonic crystals has revolutionized understanding of light-matter interactions, laying the groundwork for transformative advancements in diverse fields ranging from telecommunications to biomedical engineering.”

The award also honors Joannopoulos’ service as a “legendary mentor to generations of students, inspiring them to achieve excellence in science while at the same time facilitating the practical benefit to society through entrepreneurship.”

The Killian Award was established in 1971 to recognize outstanding professional contributions by MIT faculty members. It is the highest honor that the faculty can give to one of its members.

“I have to tell you, it was a complete and utter surprise,” Joannopoulos told MIT News shortly after he received word of the award. “I didn’t expect it at all, and was extremely flattered, honored, and moved by it, frankly.”

Joannopoulous has spent his entire professional career at MIT. He came to the Institute in 1974, directly after receiving his PhD in physics at the University of California at Berkeley, where he also earned his bachelor’s degree. Starting out as an assistant professor in MIT’s Department of Physics, he quickly set up a research program focused on theoretical condensed matter physics.

Over the first half of his MIT career, Joannopoulos worked to elucidate the fundamental nature of the electronic, vibrational, and optical structure of crystalline and amorphous bulk solids, their surfaces, interfaces, and defects. He and his students developed numerous theoretical methods to enable tractable and accurate calculations of these complex systems.

In the 1990s, his work with microscopic material systems expanded to a new class of materials, called photonic crystals — materials that could be engineered at the micro- and nanoscale to manipulate light in ways that impart surprising and exotic optical qualities to the material as a whole.

“I saw that you could create photonic crystals with defects that can affect the properties of photons, in much the same way that defects in a semiconductor affect the properties of electrons,” Joannopoulos says. “So I started working in this area to try and explore what anomalous light phenomena can we discover using this approach?”

Among his various breakthroughs in the field was the realization of a “perfect dielectric mirror” — a multilayered optical device that reflects light from all angles as normal metallic mirrors do, and that can also be tuned to reflect and trap light at specific frequencies. He and his colleagues saw potential for the mirror to be made into a hollow fiber that could serve as a highly effective optical conduit, for use in a wide range of applications. To further advance the technology, he and his colleagues launched a startup, which has since developed the technology into a flexible, fiber-optic “surgical scalpel.”

Throughout his career, Joannopoulos has helped to launch numerous startups and photonics-based technologies.

“His ability to bridge the gap between academia and industry has not only advanced scientific knowledge but also led to the creation of dozens of new companies, thousands of jobs, and groundbreaking products that continue to benefit society to this day,” the award citation states.

In 2006, Joannopoulos accepted the position as director of MIT’s Institute for Soldier Nanotechnologies (ISN), a collaboration between MIT researchers, industry partners, and military defense experts, who seek innovations to protect and enhance soldiers’ survivability in the field. In his role as ISN head, Joannopoulos has worked across MIT, making connections and supporting new projects with researchers specializing in fields far from his own.

“I get a chance to explore and learn fascinating new things,” says Joannopoulos, who is currently overseeing projects related to hyperspectral imaging, smart and responsive fabrics, and nanodrug delivery. “I love that aspect of really getting to understand what people in other fields are doing. And they’re doing great work across many, many different fields.”

Throughout his career at MIT, Joannopoulos has been especially inspired and motivated by his students, many of whom have gone on to found companies, lead top academic and research institutions, and make significant contributions to their respective fields, including one student who was awarded the Nobel Prize in Physics in 1998.

“One’s proudest moments are the successes of one’s students, and in that regard, I’ve been extremely lucky to have had truly exceptional students over the years,” Joannopolous says.

His many contributions to academia and industry have earned Joannopoulos numerous honors and awards, including his election to both the National Academy of Sciences and the American Academy of Arts and Sciences. He is also a fellow of both the American Physical Society and the American Association for the Advancement of Science.

“The Selection Committee is delighted to have this opportunity to honor Professor John Joannopoulos: a visionary scientist, a beloved mentor, a great believer in the goodness of people, and a leader whose contributions to MIT and the broader scientific community are immeasurable,” the award citation concludes.

When Paula Hammond first arrived on MIT’s campus as a first-year student in the early 1980s, she wasn’t sure if she belonged. In fact, as she told an MIT audience yesterday, she felt like “an imposter.”

However, that feeling didn’t last long, as Hammond began to find support among her fellow students and MIT’s faculty. “Community was really important for me, to feel that I belonged, to feel that I had a place here, and I found people who were willing to embrace me and support me,” she said.

Hammond, a world-renowned chemical engineer who has spent most of her academic career at MIT, made her remarks during the 2023-24 James R. Killian Jr. Faculty Achievement Award lecture.

Established in 1971 to honor MIT’s 10th president, James Killian, the Killian Award recognizes extraordinary professional achievements by an MIT faculty member. Hammond was chosen for this year’s award “not only for her tremendous professional achievements and contributions, but also for her genuine warmth and humanity, her thoughtfulness and effective leadership, and her empathy and ethics,” according to the award citation.

“Professor Hammond is a pioneer in nanotechnology research. With a program that extends from basic science to translational research in medicine and energy, she has introduced new approaches for the design and development of complex drug delivery systems for cancer treatment and noninvasive imaging,” said Mary Fuller, chair of MIT’s faculty and a professor of literature, who presented the award. “As her colleagues, we are delighted to celebrate her career today.”

In January, Hammond began serving as MIT’s vice provost for faculty. Before that, she chaired the Department of Chemical Engineering for eight years, and she was named an Institute Professor in 2021.

A versatile technique

Hammond, who grew up in Detroit, credits her parents with instilling a love of science. Her father was one of very few Black PhDs in biochemistry at the time, while her mother earned a master’s degree in nursing from Howard University and founded the nursing school at Wayne County Community College. “That provided a huge amount of opportunity for women in the area of Detroit, including women of color,” Hammond noted.

After earning her bachelor’s degree from MIT in 1984, Hammond worked as an engineer before returning to the Institute as a graduate student, earning her PhD in 1993. After a two-year postdoc at Harvard University, she returned to join the MIT faculty in 1995.

At the heart of Hammond’s research is a technique she developed to create thin films that can essentially “shrink-wrap” nanoparticles. By tuning the chemical composition of these films, the particles can be customized to deliver drugs or nucleic acids and to target specific cells in the body, including cancer cells.

To make these films, Hammond begins by layering positively charged polymers onto a negatively charged surface. Then, more layers can be added, alternating positively and negatively charged polymers. Each of these layers may contain drugs or other useful molecules, such as DNA or RNA. Some of these films contain hundreds of layers, others just one, making them useful for a wide range of applications.

“What’s nice about the layer-by-layer process is I can choose a group of degradable polymers that are nicely biocompatible, and I can alternate them with our drug materials. This means that I can build up thin film layers that contain different drugs at different points within the film,” Hammond said. “Then, when the film degrades, it can release those drugs in reverse order. This is enabling us to create complex, multidrug films, using a simple water-based technique.”

Hammond described how these layer-by-layer films can be used to promote bone growth, in an application that could help people born with congenital bone defects or people who experience traumatic injuries.

For that use, her lab has created films with layers of two proteins. One of these, BMP-2, is a protein that interacts with adult stem cells and induces them to differentiate into bone cells, generating new bone. The second is a growth factor called VEGF, which stimulates the growth of new blood vessels that help bone to regenerate. These layers are applied to a very thin tissue scaffold that can be implanted at the injury site.

Hammond and her students designed the coating so that once implanted, it would release VEGF early, over a week or so, and continue releasing BMP-2 for up to 40 days. In a study of mice, they found that this tissue scaffold stimulated the growth of new bone that was nearly indistinguishable from natural bone.

Targeting cancer

As a member of MIT’s Koch Institute for Integrative Cancer Research, Hammond has also developed layer-by-layer coatings that can improve the performance of nanoparticles used for cancer drug delivery, such as liposomes or nanoparticles made from a polymer called PLGA.

“We have a broad range of drug carriers that we can wrap this way. I think of them like a gobstopper, where there are all those different layers of candy and they dissolve one at a time,” Hammond said.

Using this approach, Hammond has created particles that can deliver a one-two punch to cancer cells. First, the particles release a dose of a nucleic acid such as short interfering RNA (siRNA), which can turn off a cancerous gene, or microRNA, which can activate tumor suppressor genes. Then, the particles release a chemotherapy drug such as cisplatin, to which the cells are now more vulnerable.

The particles also include a negatively charged outer “stealth layer” that protects them from being broken down in the bloodstream before they can reach their targets. This outer layer can also be modified to help the particles get taken up by cancer cells, by incorporating molecules that bind to proteins that are abundant on tumor cells.

In more recent work, Hammond has begun developing nanoparticles that can target ovarian cancer and help prevent recurrence of the disease after chemotherapy. In about 70 percent of ovarian cancer patients, the first round of treatment is highly effective, but tumors recur in about 85 percent of those cases, and these new tumors are usually highly drug resistant.

By altering the type of coating applied to drug-delivering nanoparticles, Hammond has found that the particles can be designed to either get inside tumor cells or stick to their surfaces. Using particles that stick to the cells, she has designed a treatment that could help to jumpstart a patient’s immune response to any recurrent tumor cells.

“With ovarian cancer, very few immune cells exist in that space, and because they don’t have a lot of immune cells present, it’s very difficult to rev up an immune response,” she said. “However, if we can deliver a molecule to neighboring cells, those few that are present, and get them revved up, then we might be able to do something.”

To that end, she designed nanoparticles that deliver IL-12, a cytokine that stimulates nearby T cells to spring into action and begin attacking tumor cells. In a study of mice, she found that this treatment induced a long-term memory T-cell response that prevented recurrence of ovarian cancer.

Hammond closed her lecture by describing the impact that the Institute has had on her throughout her career.

“It’s been a transformative experience,” she said. “I really think of this place as special because it brings people together and enables us to do things together that we couldn’t do alone. And it is that support we get from our friends, our colleagues, and our students that really makes things possible.”

When Paula Hammond first arrived on MIT’s campus as a first-year student in the early 1980s, she wasn’t sure if she belonged. In fact, as she told an MIT audience yesterday, she felt like “an imposter.”

However, that feeling didn’t last long, as Hammond began to find support among her fellow students and MIT’s faculty. “Community was really important for me, to feel that I belonged, to feel that I had a place here, and I found people who were willing to embrace me and support me,” she said.

Hammond, a world-renowned chemical engineer who has spent most of her academic career at MIT, made her remarks during the 2023-24 James R. Killian Jr. Faculty Achievement Award lecture.

Established in 1971 to honor MIT’s 10th president, James Killian, the Killian Award recognizes extraordinary professional achievements by an MIT faculty member. Hammond was chosen for this year’s award “not only for her tremendous professional achievements and contributions, but also for her genuine warmth and humanity, her thoughtfulness and effective leadership, and her empathy and ethics,” according to the award citation.

“Professor Hammond is a pioneer in nanotechnology research. With a program that extends from basic science to translational research in medicine and energy, she has introduced new approaches for the design and development of complex drug delivery systems for cancer treatment and noninvasive imaging,” said Mary Fuller, chair of MIT’s faculty and a professor of literature, who presented the award. “As her colleagues, we are delighted to celebrate her career today.”

In January, Hammond began serving as MIT’s vice provost for faculty. Before that, she chaired the Department of Chemical Engineering for eight years, and she was named an Institute Professor in 2021.

A versatile technique

Hammond, who grew up in Detroit, credits her parents with instilling a love of science. Her father was one of very few Black PhDs in biochemistry at the time, while her mother earned a master’s degree in nursing from Howard University and founded the nursing school at Wayne County Community College. “That provided a huge amount of opportunity for women in the area of Detroit, including women of color,” Hammond noted.

After earning her bachelor’s degree from MIT in 1984, Hammond worked as an engineer before returning to the Institute as a graduate student, earning her PhD in 1993. After a two-year postdoc at Harvard University, she returned to join the MIT faculty in 1995.

At the heart of Hammond’s research is a technique she developed to create thin films that can essentially “shrink-wrap” nanoparticles. By tuning the chemical composition of these films, the particles can be customized to deliver drugs or nucleic acids and to target specific cells in the body, including cancer cells.

To make these films, Hammond begins by layering positively charged polymers onto a negatively charged surface. Then, more layers can be added, alternating positively and negatively charged polymers. Each of these layers may contain drugs or other useful molecules, such as DNA or RNA. Some of these films contain hundreds of layers, others just one, making them useful for a wide range of applications.

“What’s nice about the layer-by-layer process is I can choose a group of degradable polymers that are nicely biocompatible, and I can alternate them with our drug materials. This means that I can build up thin film layers that contain different drugs at different points within the film,” Hammond said. “Then, when the film degrades, it can release those drugs in reverse order. This is enabling us to create complex, multidrug films, using a simple water-based technique.”

Hammond described how these layer-by-layer films can be used to promote bone growth, in an application that could help people born with congenital bone defects or people who experience traumatic injuries.

For that use, her lab has created films with layers of two proteins. One of these, BMP-2, is a protein that interacts with adult stem cells and induces them to differentiate into bone cells, generating new bone. The second is a growth factor called VEGF, which stimulates the growth of new blood vessels that help bone to regenerate. These layers are applied to a very thin tissue scaffold that can be implanted at the injury site.

Hammond and her students designed the coating so that once implanted, it would release VEGF early, over a week or so, and continue releasing BMP-2 for up to 40 days. In a study of mice, they found that this tissue scaffold stimulated the growth of new bone that was nearly indistinguishable from natural bone.

Targeting cancer

As a member of MIT’s Koch Institute for Integrative Cancer Research, Hammond has also developed layer-by-layer coatings that can improve the performance of nanoparticles used for cancer drug delivery, such as liposomes or nanoparticles made from a polymer called PLGA.

“We have a broad range of drug carriers that we can wrap this way. I think of them like a gobstopper, where there are all those different layers of candy and they dissolve one at a time,” Hammond said.

Using this approach, Hammond has created particles that can deliver a one-two punch to cancer cells. First, the particles release a dose of a nucleic acid such as short interfering RNA (siRNA), which can turn off a cancerous gene, or microRNA, which can activate tumor suppressor genes. Then, the particles release a chemotherapy drug such as cisplatin, to which the cells are now more vulnerable.

The particles also include a negatively charged outer “stealth layer” that protects them from being broken down in the bloodstream before they can reach their targets. This outer layer can also be modified to help the particles get taken up by cancer cells, by incorporating molecules that bind to proteins that are abundant on tumor cells.

In more recent work, Hammond has begun developing nanoparticles that can target ovarian cancer and help prevent recurrence of the disease after chemotherapy. In about 70 percent of ovarian cancer patients, the first round of treatment is highly effective, but tumors recur in about 85 percent of those cases, and these new tumors are usually highly drug resistant.

By altering the type of coating applied to drug-delivering nanoparticles, Hammond has found that the particles can be designed to either get inside tumor cells or stick to their surfaces. Using particles that stick to the cells, she has designed a treatment that could help to jumpstart a patient’s immune response to any recurrent tumor cells.

“With ovarian cancer, very few immune cells exist in that space, and because they don’t have a lot of immune cells present, it’s very difficult to rev up an immune response,” she said. “However, if we can deliver a molecule to neighboring cells, those few that are present, and get them revved up, then we might be able to do something.”

To that end, she designed nanoparticles that deliver IL-12, a cytokine that stimulates nearby T cells to spring into action and begin attacking tumor cells. In a study of mice, she found that this treatment induced a long-term memory T-cell response that prevented recurrence of ovarian cancer.

Hammond closed her lecture by describing the impact that the Institute has had on her throughout her career.

“It’s been a transformative experience,” she said. “I really think of this place as special because it brings people together and enables us to do things together that we couldn’t do alone. And it is that support we get from our friends, our colleagues, and our students that really makes things possible.”

When Paula Hammond first arrived on MIT’s campus as a first-year student in the early 1980s, she wasn’t sure if she belonged. In fact, as she told an MIT audience yesterday, she felt like “an imposter.”

However, that feeling didn’t last long, as Hammond began to find support among her fellow students and MIT’s faculty. “Community was really important for me, to feel that I belonged, to feel that I had a place here, and I found people who were willing to embrace me and support me,” she said.

Hammond, a world-renowned chemical engineer who has spent most of her academic career at MIT, made her remarks during the 2023-24 James R. Killian Jr. Faculty Achievement Award lecture.

Established in 1971 to honor MIT’s 10th president, James Killian, the Killian Award recognizes extraordinary professional achievements by an MIT faculty member. Hammond was chosen for this year’s award “not only for her tremendous professional achievements and contributions, but also for her genuine warmth and humanity, her thoughtfulness and effective leadership, and her empathy and ethics,” according to the award citation.

“Professor Hammond is a pioneer in nanotechnology research. With a program that extends from basic science to translational research in medicine and energy, she has introduced new approaches for the design and development of complex drug delivery systems for cancer treatment and noninvasive imaging,” said Mary Fuller, chair of MIT’s faculty and a professor of literature, who presented the award. “As her colleagues, we are delighted to celebrate her career today.”

In January, Hammond began serving as MIT’s vice provost for faculty. Before that, she chaired the Department of Chemical Engineering for eight years, and she was named an Institute Professor in 2021.

A versatile technique

Hammond, who grew up in Detroit, credits her parents with instilling a love of science. Her father was one of very few Black PhDs in biochemistry at the time, while her mother earned a master’s degree in nursing from Howard University and founded the nursing school at Wayne County Community College. “That provided a huge amount of opportunity for women in the area of Detroit, including women of color,” Hammond noted.

After earning her bachelor’s degree from MIT in 1984, Hammond worked as an engineer before returning to the Institute as a graduate student, earning her PhD in 1993. After a two-year postdoc at Harvard University, she returned to join the MIT faculty in 1995.

At the heart of Hammond’s research is a technique she developed to create thin films that can essentially “shrink-wrap” nanoparticles. By tuning the chemical composition of these films, the particles can be customized to deliver drugs or nucleic acids and to target specific cells in the body, including cancer cells.

To make these films, Hammond begins by layering positively charged polymers onto a negatively charged surface. Then, more layers can be added, alternating positively and negatively charged polymers. Each of these layers may contain drugs or other useful molecules, such as DNA or RNA. Some of these films contain hundreds of layers, others just one, making them useful for a wide range of applications.

“What’s nice about the layer-by-layer process is I can choose a group of degradable polymers that are nicely biocompatible, and I can alternate them with our drug materials. This means that I can build up thin film layers that contain different drugs at different points within the film,” Hammond said. “Then, when the film degrades, it can release those drugs in reverse order. This is enabling us to create complex, multidrug films, using a simple water-based technique.”

Hammond described how these layer-by-layer films can be used to promote bone growth, in an application that could help people born with congenital bone defects or people who experience traumatic injuries.

For that use, her lab has created films with layers of two proteins. One of these, BMP-2, is a protein that interacts with adult stem cells and induces them to differentiate into bone cells, generating new bone. The second is a growth factor called VEGF, which stimulates the growth of new blood vessels that help bone to regenerate. These layers are applied to a very thin tissue scaffold that can be implanted at the injury site.

Hammond and her students designed the coating so that once implanted, it would release VEGF early, over a week or so, and continue releasing BMP-2 for up to 40 days. In a study of mice, they found that this tissue scaffold stimulated the growth of new bone that was nearly indistinguishable from natural bone.

Targeting cancer

As a member of MIT’s Koch Institute for Integrative Cancer Research, Hammond has also developed layer-by-layer coatings that can improve the performance of nanoparticles used for cancer drug delivery, such as liposomes or nanoparticles made from a polymer called PLGA.

“We have a broad range of drug carriers that we can wrap this way. I think of them like a gobstopper, where there are all those different layers of candy and they dissolve one at a time,” Hammond said.

Using this approach, Hammond has created particles that can deliver a one-two punch to cancer cells. First, the particles release a dose of a nucleic acid such as short interfering RNA (siRNA), which can turn off a cancerous gene, or microRNA, which can activate tumor suppressor genes. Then, the particles release a chemotherapy drug such as cisplatin, to which the cells are now more vulnerable.

The particles also include a negatively charged outer “stealth layer” that protects them from being broken down in the bloodstream before they can reach their targets. This outer layer can also be modified to help the particles get taken up by cancer cells, by incorporating molecules that bind to proteins that are abundant on tumor cells.

In more recent work, Hammond has begun developing nanoparticles that can target ovarian cancer and help prevent recurrence of the disease after chemotherapy. In about 70 percent of ovarian cancer patients, the first round of treatment is highly effective, but tumors recur in about 85 percent of those cases, and these new tumors are usually highly drug resistant.

By altering the type of coating applied to drug-delivering nanoparticles, Hammond has found that the particles can be designed to either get inside tumor cells or stick to their surfaces. Using particles that stick to the cells, she has designed a treatment that could help to jumpstart a patient’s immune response to any recurrent tumor cells.

“With ovarian cancer, very few immune cells exist in that space, and because they don’t have a lot of immune cells present, it’s very difficult to rev up an immune response,” she said. “However, if we can deliver a molecule to neighboring cells, those few that are present, and get them revved up, then we might be able to do something.”

To that end, she designed nanoparticles that deliver IL-12, a cytokine that stimulates nearby T cells to spring into action and begin attacking tumor cells. In a study of mice, she found that this treatment induced a long-term memory T-cell response that prevented recurrence of ovarian cancer.

Hammond closed her lecture by describing the impact that the Institute has had on her throughout her career.

“It’s been a transformative experience,” she said. “I really think of this place as special because it brings people together and enables us to do things together that we couldn’t do alone. And it is that support we get from our friends, our colleagues, and our students that really makes things possible.”

When Paula Hammond first arrived on MIT’s campus as a first-year student in the early 1980s, she wasn’t sure if she belonged. In fact, as she told an MIT audience yesterday, she felt like “an imposter.”

However, that feeling didn’t last long, as Hammond began to find support among her fellow students and MIT’s faculty. “Community was really important for me, to feel that I belonged, to feel that I had a place here, and I found people who were willing to embrace me and support me,” she said.

Hammond, a world-renowned chemical engineer who has spent most of her academic career at MIT, made her remarks during the 2023-24 James R. Killian Jr. Faculty Achievement Award lecture.

Established in 1971 to honor MIT’s 10th president, James Killian, the Killian Award recognizes extraordinary professional achievements by an MIT faculty member. Hammond was chosen for this year’s award “not only for her tremendous professional achievements and contributions, but also for her genuine warmth and humanity, her thoughtfulness and effective leadership, and her empathy and ethics,” according to the award citation.

“Professor Hammond is a pioneer in nanotechnology research. With a program that extends from basic science to translational research in medicine and energy, she has introduced new approaches for the design and development of complex drug delivery systems for cancer treatment and noninvasive imaging,” said Mary Fuller, chair of MIT’s faculty and a professor of literature, who presented the award. “As her colleagues, we are delighted to celebrate her career today.”

In January, Hammond began serving as MIT’s vice provost for faculty. Before that, she chaired the Department of Chemical Engineering for eight years, and she was named an Institute Professor in 2021.

A versatile technique

Hammond, who grew up in Detroit, credits her parents with instilling a love of science. Her father was one of very few Black PhDs in biochemistry at the time, while her mother earned a master’s degree in nursing from Howard University and founded the nursing school at Wayne County Community College. “That provided a huge amount of opportunity for women in the area of Detroit, including women of color,” Hammond noted.

After earning her bachelor’s degree from MIT in 1984, Hammond worked as an engineer before returning to the Institute as a graduate student, earning her PhD in 1993. After a two-year postdoc at Harvard University, she returned to join the MIT faculty in 1995.

At the heart of Hammond’s research is a technique she developed to create thin films that can essentially “shrink-wrap” nanoparticles. By tuning the chemical composition of these films, the particles can be customized to deliver drugs or nucleic acids and to target specific cells in the body, including cancer cells.

To make these films, Hammond begins by layering positively charged polymers onto a negatively charged surface. Then, more layers can be added, alternating positively and negatively charged polymers. Each of these layers may contain drugs or other useful molecules, such as DNA or RNA. Some of these films contain hundreds of layers, others just one, making them useful for a wide range of applications.

“What’s nice about the layer-by-layer process is I can choose a group of degradable polymers that are nicely biocompatible, and I can alternate them with our drug materials. This means that I can build up thin film layers that contain different drugs at different points within the film,” Hammond said. “Then, when the film degrades, it can release those drugs in reverse order. This is enabling us to create complex, multidrug films, using a simple water-based technique.”

Hammond described how these layer-by-layer films can be used to promote bone growth, in an application that could help people born with congenital bone defects or people who experience traumatic injuries.

For that use, her lab has created films with layers of two proteins. One of these, BMP-2, is a protein that interacts with adult stem cells and induces them to differentiate into bone cells, generating new bone. The second is a growth factor called VEGF, which stimulates the growth of new blood vessels that help bone to regenerate. These layers are applied to a very thin tissue scaffold that can be implanted at the injury site.

Hammond and her students designed the coating so that once implanted, it would release VEGF early, over a week or so, and continue releasing BMP-2 for up to 40 days. In a study of mice, they found that this tissue scaffold stimulated the growth of new bone that was nearly indistinguishable from natural bone.

Targeting cancer

As a member of MIT’s Koch Institute for Integrative Cancer Research, Hammond has also developed layer-by-layer coatings that can improve the performance of nanoparticles used for cancer drug delivery, such as liposomes or nanoparticles made from a polymer called PLGA.

“We have a broad range of drug carriers that we can wrap this way. I think of them like a gobstopper, where there are all those different layers of candy and they dissolve one at a time,” Hammond said.

Using this approach, Hammond has created particles that can deliver a one-two punch to cancer cells. First, the particles release a dose of a nucleic acid such as short interfering RNA (siRNA), which can turn off a cancerous gene, or microRNA, which can activate tumor suppressor genes. Then, the particles release a chemotherapy drug such as cisplatin, to which the cells are now more vulnerable.

The particles also include a negatively charged outer “stealth layer” that protects them from being broken down in the bloodstream before they can reach their targets. This outer layer can also be modified to help the particles get taken up by cancer cells, by incorporating molecules that bind to proteins that are abundant on tumor cells.

In more recent work, Hammond has begun developing nanoparticles that can target ovarian cancer and help prevent recurrence of the disease after chemotherapy. In about 70 percent of ovarian cancer patients, the first round of treatment is highly effective, but tumors recur in about 85 percent of those cases, and these new tumors are usually highly drug resistant.

By altering the type of coating applied to drug-delivering nanoparticles, Hammond has found that the particles can be designed to either get inside tumor cells or stick to their surfaces. Using particles that stick to the cells, she has designed a treatment that could help to jumpstart a patient’s immune response to any recurrent tumor cells.

“With ovarian cancer, very few immune cells exist in that space, and because they don’t have a lot of immune cells present, it’s very difficult to rev up an immune response,” she said. “However, if we can deliver a molecule to neighboring cells, those few that are present, and get them revved up, then we might be able to do something.”

To that end, she designed nanoparticles that deliver IL-12, a cytokine that stimulates nearby T cells to spring into action and begin attacking tumor cells. In a study of mice, she found that this treatment induced a long-term memory T-cell response that prevented recurrence of ovarian cancer.

Hammond closed her lecture by describing the impact that the Institute has had on her throughout her career.

“It’s been a transformative experience,” she said. “I really think of this place as special because it brings people together and enables us to do things together that we couldn’t do alone. And it is that support we get from our friends, our colleagues, and our students that really makes things possible.”

Today, MIT Professor Moungi Bawendi won a share of the 2023 Nobel Prize in Chemistry, for his role in developing quantum dots — nanoscale particles that can emit exceedingly bright light. Bawendi, a professor of chemistry who has been on the MIT faculty since 1990, told MIT News this morning that he felt “surprise and shock” upon receiving the call from the Nobel committee from his home in Cambridge, Massachusetts, adding, “It was such an honor to wake up to.”

The following images provide a brief snapshot of his first day as a Nobel laureate.

Early this morning, Bawendi received a phone call from Nobel Prize officials in Sweden, letting him know that he had won a share of this year’s chemistry prize. Hear some of his first reactions via a Nobel Prize phone interview.

Bawendi took his first questions from the media during a 5:45 a.m. (ET) press conference hosted by the Royal Swedish Academy of Sciences in Stockholm to announce this year’s winners. Watch the full press conference.

He quickly began to receive texts and calls from family, friends, colleagues, and more.

Media crews soon arrived at his home in Cambridge, where his wife, Rachel Zimmerman; stepdaughter, Julia Teller; and very good dog Phoebe were celebrating with him.

The Nobel laureate joined Phoebe for official MIT portrait photos.

Bawendi arrived at the MIT campus shortly before he was scheduled to teach, and was greeted with applause and festive food and drinks from his colleagues and students.

Following a sartorial update, Bawendi prepared to teach his 9 a.m. class, greeting more colleagues and students in the Department of Chemistry.

Bawendi ended up scrapping plans for his class, 5.73 (Introduction to Quantum Mechanics), switching from a normal lesson to a brief history of his work on quantum dot science. The class “went very well, except I didn’t talk about what I was supposed to talk about,” he joked afterward, at an MIT press conference.

After class, the professor of chemistry made time to take photos with students.

An MIT press conference, hosted by the Institute Office of Communications and President Sally Kornbluth, was held at 10:30 a.m. ET. Watch the full press conference.

After lunch, Bawendi met in person with President Kornbluth.

In the late afternoon, toasts were made at a celebration for Bawendi organized by the Department of Chemistry.

Moungi Bawendi, the Lester Wolfe Professor of Chemistry at MIT and a leader in the development of tiny particles known as quantum dots, has won the Nobel Prize in Chemistry for 2023. He will share the prize with Louis Brus of Columbia University and Alexei Ekimov of Nanocrystals Technology, Inc.

The researchers were honored for their work in discovering and synthesizing quantum dots — tiny particles of matter that emit exceptionally pure light. In its announcement this morning, the Nobel Foundation cited Bawendi for work that “revolutionized the chemical production of quantum dots, resulting in almost perfect particles.”

Bawendi, who has been a professor at MIT since 1990, told MIT News this morning that he felt “surprise and shock” upon receiving the call from the Nobel committee, adding, “It was such an honor to wake up to.”

Quantum dots consist of tiny particles of semiconductor material that are so small that their properties differ from those of the bulk material. Instead, they are governed in part by the laws of quantum mechanics that describe how atoms and subatomic particles behave. When illuminated with ultraviolet light, the dots fluoresce brightly in a range of colors determined by the sizes of the particles.

These tiny particles are now used in many types of biomedical imaging, as well as computer and television displays, and they also hold potential in fields such as photocatalysis and quantum computing.

“It’s hard to think of a more elegant expression of Mind and Hand,” MIT President Sally Kornbluth wrote about Bawendi’s work, in a letter to the MIT community this morning, in reference to MIT’s motto, “Mens et Manus.” “We join Moungi’s family, his department, and his friends and colleagues around the world in celebrating this rare honor.”

Sculpting tiny particles

Quantum dots are particles only a few nanometers in diameter — about one-millionth the size of a pinhead. Since the 1930s, scientists had predicted that particles so tiny would show unusual behavior because at such tiny scales there is less space for a material’s electrons, so they become squeezed together. As a result, it was believed that the particles’ size would influence physical properties such as color.

However, this hypothesis was difficult to test because there were no ways to produce such tiny particles — until the early 1980s, when Ekimov and Brus independently succeeded at creating quantum dots. Working with quantum dots floating freely in a solution, Brus demonstrated that the size of the particles affected the color that they emitted. Ekimov discovered the same phenomenon working with nanoparticles of glass tinted with copper chloride.

The techniques used by Ekimov and Brus, however, did not yield quantum dots of uniform size. In 1993, Bawendi and his students were the first to report a method for synthesizing quantum dots while maintaining precise control over their size.

By systematically varying the conditions under which the quantum dots were crystallized, Bawendi and his research group succeeded in growing nanocrystals of a specific size. At the time, the researchers were interested in making quantum dots so they could further study their unique properties, with no inkling of what they would later become useful for.

“We just pushed and pushed, and we eventually developed a process to make particles good enough for basic science studies, and it turned out the process could be used for far more than that, which we never would have thought at the time,” Bawendi told MIT News.

Since then, he has also devised ways to control the efficiency of the dots’ light emission and to eliminate their tendency to blink on and off, making them more practical for applications in many fields.

Quantum dots are now used in flat screen TVs and other displays, where they generate more vivid images than traditional LED screens. They are also used to label molecules inside cells, allowing them to be imaged more easily, and they have been explored as a tool to guide doctors during surgery by illuminating tissue.

“It’s really great to see how they have been used in so many areas, but it’s not something we were expecting at the time,” says Bawendi, who is also a core member of the Microsystems Technology Laboratories at MIT. “We were just interested in studying the materials.”

Introducing Bawendi at an MIT press conference this morning, Kornbluth described his Nobel achievement as “a banner day” for the Institute.

“We cannot imagine anything more electrifying,” Kornbluth said. “Obviously, that excitement reflects our respect for this extraordinary honor, but it runs deeper because you'd be hard pressed to find a community with a greater reverence for the wondrous beauty of basic discovery science and the incredible power of innovation to better our world than the people of MIT. I hope this award and all of this week's science Nobels can serve to remind the nation and the world of why fundamental science deserves our sustained and enthusiastic support.”

A new field of science

Born in Paris to a French mother and Tunisian father, Bawendi moved to West Lafayette, Indiana, as a young boy when his father, a mathematician, became a professor at Purdue University. In 1982, he earned his undergraduate degree from Harvard University, where as a first-year student, he failed his first chemistry exam. That experience taught him a valuable lesson in perseverance, which he described at today’s press conference.

“You have a setback, but you can persevere and overcome this and learn from your experience, which obviously I did,” he said. “And I could have just decided this wasn't for me, but I liked what I was doing, and so I learned how to become successful as a student.”

Bawendi went on to earn a PhD from the University of Chicago in 1988. As a postdoc, he worked with Brus, who was then at AT&T Bell Laboratories and had recently made his original discovery regarding the properties of different sized quantum dots.

“That was what made me excited to work with him, because it opened up a brand new field of science, which creates a lot of opportunity to make new discoveries,” Bawendi told MIT News.

Scientists are now exploring the possibility of using quantum dots to improve the performance of many other technologies, including solar cells, flexible electronics, and photocatalysts. In recent years, Bawendi’s lab has also developed spectrometers based on quantum dots, which are small enough to fit inside a smartphone camera. Such devices could be used to diagnose diseases, especially skin conditions, or to detect environmental pollutants.

When asked at the press conference what the future might hold for quantum dot research, Bawendi said he expects to be surprised.

“That's a really good question because I'm constantly surprised when I go to conferences about the progress and the directions of the field,” he said. “I think 30 years ago, none of us who started the field could have predicted 30 years later we’d be where we are today. And it's just amazing to me, if you have really great people working on a brand new field with brand new materials, innovation comes out in directions that you can't predict.”

Being at MIT, with its focus on interdisciplinary research, has been a critical factor in his success, Bawendi told MIT News.

“The atmosphere at MIT is really what allowed me to explore other fields of science, which has been key to the advances I’ve been able to make,” he says. “It’s a unique place, and it’s wonderful to be part of it.”

Today, MIT Professor Moungi Bawendi won a share of the 2023 Nobel Prize in Chemistry, for his role in developing quantum dots — nanoscale particles that can emit exceedingly bright light. Bawendi, a professor of chemistry who has been on the MIT faculty since 1990, told MIT News this morning that he felt “surprise and shock” upon receiving the call from the Nobel committee from his home in Cambridge, Massachusetts, adding, “It was such an honor to wake up to.”

The following images provide a brief snapshot of his first day as a Nobel laureate.

Early this morning, Bawendi received a phone call from Nobel Prize officials in Sweden, letting him know that he had won a share of this year’s chemistry prize. Hear some of his first reactions via a Nobel Prize phone interview.

Bawendi took his first questions from the media during a 5:45 a.m. (ET) press conference hosted by the Royal Swedish Academy of Sciences in Stockholm to announce this year’s winners. Watch the full press conference.

He quickly began to receive texts and calls from family, friends, colleagues, and more.

Media crews soon arrived at his home in Cambridge, where his wife, Rachel Zimmerman; stepdaughter, Julia Teller; and very good dog Phoebe were celebrating with him.

The Nobel laureate joined Phoebe for official MIT portrait photos.

Bawendi arrived at the MIT campus shortly before he was scheduled to teach, and was greeted with applause and festive food and drinks from his colleagues and students.

Following a sartorial update, Bawendi prepared to teach his 9 a.m. class, greeting more colleagues and students in the Department of Chemistry.

Bawendi ended up scrapping plans for his class, 5.73 (Introduction to Quantum Mechanics), switching from a normal lesson to a brief history of his work on quantum dot science. The class “went very well, except I didn’t talk about what I was supposed to talk about,” he joked afterward, at an MIT press conference.

After class, the professor of chemistry made time to take photos with students.

An MIT press conference, hosted by the Institute Office of Communications and President Sally Kornbluth, was held at 10:30 a.m. ET. Watch the full press conference.

After lunch, Bawendi met in person with President Kornbluth.

In the late afternoon, toasts were made at a celebration for Bawendi organized by the Department of Chemistry.

Moungi Bawendi, the Lester Wolfe Professor of Chemistry at MIT and a leader in the development of tiny particles known as quantum dots, has won the Nobel Prize in Chemistry for 2023. He will share the prize with Louis Brus of Columbia University and Alexei Ekimov of Nanocrystals Technology, Inc.

The researchers were honored for their work in discovering and synthesizing quantum dots — tiny particles of matter that emit exceptionally pure light. In its announcement this morning, the Nobel Foundation cited Bawendi for work that “revolutionized the chemical production of quantum dots, resulting in almost perfect particles.”

Bawendi, who has been a professor at MIT since 1990, told MIT News this morning that he felt “surprise and shock” upon receiving the call from the Nobel committee, adding, “It was such an honor to wake up to.”

Quantum dots consist of tiny particles of semiconductor material that are so small that their properties differ from those of the bulk material. Instead, they are governed in part by the laws of quantum mechanics that describe how atoms and subatomic particles behave. When illuminated with ultraviolet light, the dots fluoresce brightly in a range of colors determined by the sizes of the particles.

These tiny particles are now used in many types of biomedical imaging, as well as computer and television displays, and they also hold potential in fields such as photocatalysis and quantum computing.

“It’s hard to think of a more elegant expression of Mind and Hand,” MIT President Sally Kornbluth wrote about Bawendi’s work, in a letter to the MIT community this morning, in reference to MIT’s motto, “Mens et Manus.” “We join Moungi’s family, his department, and his friends and colleagues around the world in celebrating this rare honor.”

Sculpting tiny particles

Quantum dots are particles only a few nanometers in diameter — about one-millionth the size of a pinhead. Since the 1930s, scientists had predicted that particles so tiny would show unusual behavior because at such tiny scales there is less space for a material’s electrons, so they become squeezed together. As a result, it was believed that the particles’ size would influence physical properties such as color.

However, this hypothesis was difficult to test because there were no ways to produce such tiny particles — until the early 1980s, when Ekimov and Brus independently succeeded at creating quantum dots. Working with quantum dots floating freely in a solution, Brus demonstrated that the size of the particles affected the color that they emitted. Ekimov discovered the same phenomenon working with nanoparticles of glass tinted with copper chloride.

The techniques used by Ekimov and Brus, however, did not yield quantum dots of uniform size. In 1993, Bawendi and his students were the first to report a method for synthesizing quantum dots while maintaining precise control over their size.

By systematically varying the conditions under which the quantum dots were crystallized, Bawendi and his research group succeeded in growing nanocrystals of a specific size. At the time, the researchers were interested in making quantum dots so they could further study their unique properties, with no inkling of what they would later become useful for.

“We just pushed and pushed, and we eventually developed a process to make particles good enough for basic science studies, and it turned out the process could be used for far more than that, which we never would have thought at the time,” Bawendi told MIT News.

Since then, he has also devised ways to control the efficiency of the dots’ light emission and to eliminate their tendency to blink on and off, making them more practical for applications in many fields.

Quantum dots are now used in flat screen TVs and other displays, where they generate more vivid images than traditional LED screens. They are also used to label molecules inside cells, allowing them to be imaged more easily, and they have been explored as a tool to guide doctors during surgery by illuminating tissue.

“It’s really great to see how they have been used in so many areas, but it’s not something we were expecting at the time,” says Bawendi, who is also a core member of the Microsystems Technology Laboratories at MIT. “We were just interested in studying the materials.”

Introducing Bawendi at an MIT press conference this morning, Kornbluth described his Nobel achievement as “a banner day” for the Institute.

“We cannot imagine anything more electrifying,” Kornbluth said. “Obviously, that excitement reflects our respect for this extraordinary honor, but it runs deeper because you'd be hard pressed to find a community with a greater reverence for the wondrous beauty of basic discovery science and the incredible power of innovation to better our world than the people of MIT. I hope this award and all of this week's science Nobels can serve to remind the nation and the world of why fundamental science deserves our sustained and enthusiastic support.”

A new field of science

Born in Paris to a French mother and Tunisian father, Bawendi moved to West Lafayette, Indiana, as a young boy when his father, a mathematician, became a professor at Purdue University. In 1982, he earned his undergraduate degree from Harvard University, where as a first-year student, he failed his first chemistry exam. That experience taught him a valuable lesson in perseverance, which he described at today’s press conference.

“You have a setback, but you can persevere and overcome this and learn from your experience, which obviously I did,” he said. “And I could have just decided this wasn't for me, but I liked what I was doing, and so I learned how to become successful as a student.”

Bawendi went on to earn a PhD from the University of Chicago in 1988. As a postdoc, he worked with Brus, who was then at AT&T Bell Laboratories and had recently made his original discovery regarding the properties of different sized quantum dots.

“That was what made me excited to work with him, because it opened up a brand new field of science, which creates a lot of opportunity to make new discoveries,” Bawendi told MIT News.

Scientists are now exploring the possibility of using quantum dots to improve the performance of many other technologies, including solar cells, flexible electronics, and photocatalysts. In recent years, Bawendi’s lab has also developed spectrometers based on quantum dots, which are small enough to fit inside a smartphone camera. Such devices could be used to diagnose diseases, especially skin conditions, or to detect environmental pollutants.

When asked at the press conference what the future might hold for quantum dot research, Bawendi said he expects to be surprised.

“That's a really good question because I'm constantly surprised when I go to conferences about the progress and the directions of the field,” he said. “I think 30 years ago, none of us who started the field could have predicted 30 years later we’d be where we are today. And it's just amazing to me, if you have really great people working on a brand new field with brand new materials, innovation comes out in directions that you can't predict.”

Being at MIT, with its focus on interdisciplinary research, has been a critical factor in his success, Bawendi told MIT News.

“The atmosphere at MIT is really what allowed me to explore other fields of science, which has been key to the advances I’ve been able to make,” he says. “It’s a unique place, and it’s wonderful to be part of it.”

Today, MIT Professor Moungi Bawendi won a share of the 2023 Nobel Prize in Chemistry, for his role in developing quantum dots — nanoscale particles that can emit exceedingly bright light. Bawendi, a professor of chemistry who has been on the MIT faculty since 1990, told MIT News this morning that he felt “surprise and shock” upon receiving the call from the Nobel committee from his home in Cambridge, Massachusetts, adding, “It was such an honor to wake up to.”

The following images provide a brief snapshot of his first day as a Nobel laureate.

Early this morning, Bawendi received a phone call from Nobel Prize officials in Sweden, letting him know that he had won a share of this year’s chemistry prize. Hear some of his first reactions via a Nobel Prize phone interview.

Bawendi took his first questions from the media during a 5:45 a.m. (ET) press conference hosted by the Royal Swedish Academy of Sciences in Stockholm to announce this year’s winners. Watch the full press conference.

He quickly began to receive texts and calls from family, friends, colleagues, and more.

Media crews soon arrived at his home in Cambridge, where his wife, Rachel Zimmerman; stepdaughter, Julia Teller; and very good dog Phoebe were celebrating with him.

The Nobel laureate joined Phoebe for official MIT portrait photos.

Bawendi arrived at the MIT campus shortly before he was scheduled to teach, and was greeted with applause and festive food and drinks from his colleagues and students.

Following a sartorial update, Bawendi prepared to teach his 9 a.m. class, greeting more colleagues and students in the Department of Chemistry.

Bawendi ended up scrapping plans for his class, 5.73 (Introduction to Quantum Mechanics), switching from a normal lesson to a brief history of his work on quantum dot science. The class “went very well, except I didn’t talk about what I was supposed to talk about,” he joked afterward, at an MIT press conference.

After class, the professor of chemistry made time to take photos with students.

An MIT press conference, hosted by the Institute Office of Communications and President Sally Kornbluth, was held at 10:30 a.m. ET. Watch the full press conference.

After lunch, Bawendi met in person with President Kornbluth.

In the late afternoon, toasts were made at a celebration for Bawendi organized by the Department of Chemistry.

Moungi Bawendi, the Lester Wolfe Professor of Chemistry at MIT and a leader in the development of tiny particles known as quantum dots, has won the Nobel Prize in Chemistry for 2023. He will share the prize with Louis Brus of Columbia University and Alexei Ekimov of Nanocrystals Technology, Inc.

The researchers were honored for their work in discovering and synthesizing quantum dots — tiny particles of matter that emit exceptionally pure light. In its announcement this morning, the Nobel Foundation cited Bawendi for work that “revolutionized the chemical production of quantum dots, resulting in almost perfect particles.”

Bawendi, who has been a professor at MIT since 1990, told MIT News this morning that he felt “surprise and shock” upon receiving the call from the Nobel committee, adding, “It was such an honor to wake up to.”

Quantum dots consist of tiny particles of semiconductor material that are so small that their properties differ from those of the bulk material. Instead, they are governed in part by the laws of quantum mechanics that describe how atoms and subatomic particles behave. When illuminated with ultraviolet light, the dots fluoresce brightly in a range of colors determined by the sizes of the particles.

These tiny particles are now used in many types of biomedical imaging, as well as computer and television displays, and they also hold potential in fields such as photocatalysis and quantum computing.

“It’s hard to think of a more elegant expression of Mind and Hand,” MIT President Sally Kornbluth wrote about Bawendi’s work, in a letter to the MIT community this morning, in reference to MIT’s motto, “Mens et Manus.” “We join Moungi’s family, his department, and his friends and colleagues around the world in celebrating this rare honor.”

Sculpting tiny particles

Quantum dots are particles only a few nanometers in diameter — about one-millionth the size of a pinhead. Since the 1930s, scientists had predicted that particles so tiny would show unusual behavior because at such tiny scales there is less space for a material’s electrons, so they become squeezed together. As a result, it was believed that the particles’ size would influence physical properties such as color.

However, this hypothesis was difficult to test because there were no ways to produce such tiny particles — until the early 1980s, when Ekimov and Brus independently succeeded at creating quantum dots. Working with quantum dots floating freely in a solution, Brus demonstrated that the size of the particles affected the color that they emitted. Ekimov discovered the same phenomenon working with nanoparticles of glass tinted with copper chloride.

The techniques used by Ekimov and Brus, however, did not yield quantum dots of uniform size. In 1993, Bawendi and his students were the first to report a method for synthesizing quantum dots while maintaining precise control over their size.

By systematically varying the conditions under which the quantum dots were crystallized, Bawendi and his research group succeeded in growing nanocrystals of a specific size. At the time, the researchers were interested in making quantum dots so they could further study their unique properties, with no inkling of what they would later become useful for.

“We just pushed and pushed, and we eventually developed a process to make particles good enough for basic science studies, and it turned out the process could be used for far more than that, which we never would have thought at the time,” Bawendi told MIT News.

Since then, he has also devised ways to control the efficiency of the dots’ light emission and to eliminate their tendency to blink on and off, making them more practical for applications in many fields.

Quantum dots are now used in flat screen TVs and other displays, where they generate more vivid images than traditional LED screens. They are also used to label molecules inside cells, allowing them to be imaged more easily, and they have been explored as a tool to guide doctors during surgery by illuminating tissue.

“It’s really great to see how they have been used in so many areas, but it’s not something we were expecting at the time,” says Bawendi, who is also a core member of the Microsystems Technology Laboratories at MIT. “We were just interested in studying the materials.”

Introducing Bawendi at an MIT press conference this morning, Kornbluth described his Nobel achievement as “a banner day” for the Institute.

“We cannot imagine anything more electrifying,” Kornbluth said. “Obviously, that excitement reflects our respect for this extraordinary honor, but it runs deeper because you'd be hard pressed to find a community with a greater reverence for the wondrous beauty of basic discovery science and the incredible power of innovation to better our world than the people of MIT. I hope this award and all of this week's science Nobels can serve to remind the nation and the world of why fundamental science deserves our sustained and enthusiastic support.”

A new field of science

Born in Paris to a French mother and Tunisian father, Bawendi moved to West Lafayette, Indiana, as a young boy when his father, a mathematician, became a professor at Purdue University. In 1982, he earned his undergraduate degree from Harvard University, where as a first-year student, he failed his first chemistry exam. That experience taught him a valuable lesson in perseverance, which he described at today’s press conference.

“You have a setback, but you can persevere and overcome this and learn from your experience, which obviously I did,” he said. “And I could have just decided this wasn't for me, but I liked what I was doing, and so I learned how to become successful as a student.”

Bawendi went on to earn a PhD from the University of Chicago in 1988. As a postdoc, he worked with Brus, who was then at AT&T Bell Laboratories and had recently made his original discovery regarding the properties of different sized quantum dots.

“That was what made me excited to work with him, because it opened up a brand new field of science, which creates a lot of opportunity to make new discoveries,” Bawendi told MIT News.

Scientists are now exploring the possibility of using quantum dots to improve the performance of many other technologies, including solar cells, flexible electronics, and photocatalysts. In recent years, Bawendi’s lab has also developed spectrometers based on quantum dots, which are small enough to fit inside a smartphone camera. Such devices could be used to diagnose diseases, especially skin conditions, or to detect environmental pollutants.

When asked at the press conference what the future might hold for quantum dot research, Bawendi said he expects to be surprised.

“That's a really good question because I'm constantly surprised when I go to conferences about the progress and the directions of the field,” he said. “I think 30 years ago, none of us who started the field could have predicted 30 years later we’d be where we are today. And it's just amazing to me, if you have really great people working on a brand new field with brand new materials, innovation comes out in directions that you can't predict.”

Being at MIT, with its focus on interdisciplinary research, has been a critical factor in his success, Bawendi told MIT News.

“The atmosphere at MIT is really what allowed me to explore other fields of science, which has been key to the advances I’ve been able to make,” he says. “It’s a unique place, and it’s wonderful to be part of it.”

Today, MIT Professor Moungi Bawendi won a share of the 2023 Nobel Prize in Chemistry, for his role in developing quantum dots — nanoscale particles that can emit exceedingly bright light. Bawendi, a professor of chemistry who has been on the MIT faculty since 1990, told MIT News this morning that he felt “surprise and shock” upon receiving the call from the Nobel committee from his home in Cambridge, Massachusetts, adding, “It was such an honor to wake up to.”

The following images provide a brief snapshot of his first day as a Nobel laureate.

Early this morning, Bawendi received a phone call from Nobel Prize officials in Sweden, letting him know that he had won a share of this year’s chemistry prize. Hear some of his first reactions via a Nobel Prize phone interview.

Bawendi took his first questions from the media during a 5:45 a.m. (ET) press conference hosted by the Royal Swedish Academy of Sciences in Stockholm to announce this year’s winners. Watch the full press conference.

He quickly began to receive texts and calls from family, friends, colleagues, and more.

Media crews soon arrived at his home in Cambridge, where his wife, Rachel Zimmerman; stepdaughter, Julia Teller; and very good dog Phoebe were celebrating with him.

The Nobel laureate joined Phoebe for official MIT portrait photos.

Bawendi arrived at the MIT campus shortly before he was scheduled to teach, and was greeted with applause and festive food and drinks from his colleagues and students.

Following a sartorial update, Bawendi prepared to teach his 9 a.m. class, greeting more colleagues and students in the Department of Chemistry.

Bawendi ended up scrapping plans for his class, 5.73 (Introduction to Quantum Mechanics), switching from a normal lesson to a brief history of his work on quantum dot science. The class “went very well, except I didn’t talk about what I was supposed to talk about,” he joked afterward, at an MIT press conference.

After class, the professor of chemistry made time to take photos with students.

An MIT press conference, hosted by the Institute Office of Communications and President Sally Kornbluth, was held at 10:30 a.m. ET. Watch the full press conference.

After lunch, Bawendi met in person with President Kornbluth.

In the late afternoon, toasts were made at a celebration for Bawendi organized by the Department of Chemistry.

Moungi Bawendi, the Lester Wolfe Professor of Chemistry at MIT and a leader in the development of tiny particles known as quantum dots, has won the Nobel Prize in Chemistry for 2023. He will share the prize with Louis Brus of Columbia University and Alexei Ekimov of Nanocrystals Technology, Inc.

The researchers were honored for their work in discovering and synthesizing quantum dots — tiny particles of matter that emit exceptionally pure light. In its announcement this morning, the Nobel Foundation cited Bawendi for work that “revolutionized the chemical production of quantum dots, resulting in almost perfect particles.”

Bawendi, who has been a professor at MIT since 1990, told MIT News this morning that he felt “surprise and shock” upon receiving the call from the Nobel committee, adding, “It was such an honor to wake up to.”

Quantum dots consist of tiny particles of semiconductor material that are so small that their properties differ from those of the bulk material. Instead, they are governed in part by the laws of quantum mechanics that describe how atoms and subatomic particles behave. When illuminated with ultraviolet light, the dots fluoresce brightly in a range of colors determined by the sizes of the particles.

These tiny particles are now used in many types of biomedical imaging, as well as computer and television displays, and they also hold potential in fields such as photocatalysis and quantum computing.

“It’s hard to think of a more elegant expression of Mind and Hand,” MIT President Sally Kornbluth wrote about Bawendi’s work, in a letter to the MIT community this morning, in reference to MIT’s motto, “Mens et Manus.” “We join Moungi’s family, his department, and his friends and colleagues around the world in celebrating this rare honor.”

Sculpting tiny particles

Quantum dots are particles only a few nanometers in diameter — about one-millionth the size of a pinhead. Since the 1930s, scientists had predicted that particles so tiny would show unusual behavior because at such tiny scales there is less space for a material’s electrons, so they become squeezed together. As a result, it was believed that the particles’ size would influence physical properties such as color.

However, this hypothesis was difficult to test because there were no ways to produce such tiny particles — until the early 1980s, when Ekimov and Brus independently succeeded at creating quantum dots. Working with quantum dots floating freely in a solution, Brus demonstrated that the size of the particles affected the color that they emitted. Ekimov discovered the same phenomenon working with nanoparticles of glass tinted with copper chloride.

The techniques used by Ekimov and Brus, however, did not yield quantum dots of uniform size. In 1993, Bawendi and his students were the first to report a method for synthesizing quantum dots while maintaining precise control over their size.

By systematically varying the conditions under which the quantum dots were crystallized, Bawendi and his research group succeeded in growing nanocrystals of a specific size. At the time, the researchers were interested in making quantum dots so they could further study their unique properties, with no inkling of what they would later become useful for.

“We just pushed and pushed, and we eventually developed a process to make particles good enough for basic science studies, and it turned out the process could be used for far more than that, which we never would have thought at the time,” Bawendi told MIT News.

Since then, he has also devised ways to control the efficiency of the dots’ light emission and to eliminate their tendency to blink on and off, making them more practical for applications in many fields.

Quantum dots are now used in flat screen TVs and other displays, where they generate more vivid images than traditional LED screens. They are also used to label molecules inside cells, allowing them to be imaged more easily, and they have been explored as a tool to guide doctors during surgery by illuminating tissue.

“It’s really great to see how they have been used in so many areas, but it’s not something we were expecting at the time,” says Bawendi, who is also a core member of the Microsystems Technology Laboratories at MIT. “We were just interested in studying the materials.”

Introducing Bawendi at an MIT press conference this morning, Kornbluth described his Nobel achievement as “a banner day” for the Institute.

“We cannot imagine anything more electrifying,” Kornbluth said. “Obviously, that excitement reflects our respect for this extraordinary honor, but it runs deeper because you'd be hard pressed to find a community with a greater reverence for the wondrous beauty of basic discovery science and the incredible power of innovation to better our world than the people of MIT. I hope this award and all of this week's science Nobels can serve to remind the nation and the world of why fundamental science deserves our sustained and enthusiastic support.”

A new field of science

Born in Paris to a French mother and Tunisian father, Bawendi moved to West Lafayette, Indiana, as a young boy when his father, a mathematician, became a professor at Purdue University. In 1982, he earned his undergraduate degree from Harvard University, where as a first-year student, he failed his first chemistry exam. That experience taught him a valuable lesson in perseverance, which he described at today’s press conference.

“You have a setback, but you can persevere and overcome this and learn from your experience, which obviously I did,” he said. “And I could have just decided this wasn't for me, but I liked what I was doing, and so I learned how to become successful as a student.”

Bawendi went on to earn a PhD from the University of Chicago in 1988. As a postdoc, he worked with Brus, who was then at AT&T Bell Laboratories and had recently made his original discovery regarding the properties of different sized quantum dots.

“That was what made me excited to work with him, because it opened up a brand new field of science, which creates a lot of opportunity to make new discoveries,” Bawendi told MIT News.

Scientists are now exploring the possibility of using quantum dots to improve the performance of many other technologies, including solar cells, flexible electronics, and photocatalysts. In recent years, Bawendi’s lab has also developed spectrometers based on quantum dots, which are small enough to fit inside a smartphone camera. Such devices could be used to diagnose diseases, especially skin conditions, or to detect environmental pollutants.

When asked at the press conference what the future might hold for quantum dot research, Bawendi said he expects to be surprised.

“That's a really good question because I'm constantly surprised when I go to conferences about the progress and the directions of the field,” he said. “I think 30 years ago, none of us who started the field could have predicted 30 years later we’d be where we are today. And it's just amazing to me, if you have really great people working on a brand new field with brand new materials, innovation comes out in directions that you can't predict.”

Being at MIT, with its focus on interdisciplinary research, has been a critical factor in his success, Bawendi told MIT News.

“The atmosphere at MIT is really what allowed me to explore other fields of science, which has been key to the advances I’ve been able to make,” he says. “It’s a unique place, and it’s wonderful to be part of it.”