Gabrielle Wood, a junior at Howard University majoring in chemical engineering, is on a mission to improve the sustainability and life cycles of natural resources and materials. Her work in the Materials Initiative for Comprehensive Research Opportunity (MICRO) program has given her hands-on experience with many different aspects of research, including MATLAB programming, experimental design, data analysis, figure-making, and scientific writing.

Wood is also one of 10 undergraduates from 10 universities around the United States to participate in the first MICRO Summit earlier this year. The internship program, developed by the MIT Department of Materials Science and Engineering (DMSE), first launched in fall 2021. Now in its third year, the program continues to grow, providing even more opportunities for non-MIT undergraduate students — including the MICRO Summit and the program’s expansion to include Northwestern University.

“I think one of the most valuable aspects of the MICRO program is the ability to do research long term with an experienced professor in materials science and engineering,” says Wood. “My school has limited opportunities for undergraduate research in sustainable polymers, so the MICRO program allowed me to gain valuable experience in this field, which I would not otherwise have.”

Like Wood, Griheydi Garcia, a senior chemistry major at Manhattan College, values the exposure to materials science, especially since she is not able to learn as much about it at her home institution.

“I learned a lot about crystallography and defects in materials through the MICRO curriculum, especially through videos,” says Garcia. “The research itself is very valuable, as well, because we get to apply what we’ve learned through the videos in the research we do remotely.”

Expanding research opportunities

From the beginning, the MICRO program was designed as a fully remote, rigorous education and mentoring program targeted toward students from underserved backgrounds interested in pursuing graduate school in materials science or related fields. Interns are matched with faculty to work on their specific research interests.

Jessica Sandland ’99, PhD ’05, principal lecturer in DMSE and co-founder of MICRO, says that research projects for the interns are designed to be work that they can do remotely, such as developing a machine-learning algorithm or a data analysis approach.

“It’s important to note that it’s not just about what the program and faculty are bringing to the student interns,” says Sandland, a member of the MIT Digital Learning Lab, a joint program between MIT Open Learning and the Institute’s academic departments. “The students are doing real research and work, and creating things of real value. It’s very much an exchange.”

Cécile Chazot PhD ’22, now an assistant professor of materials science and engineering at Northwestern University, had helped to establish MICRO at MIT from the very beginning. Once at Northwestern, she quickly realized that expanding MICRO to Northwestern would offer even more research opportunities to interns than by relying on MIT alone — leveraging the university’s strong materials science and engineering department, as well as offering resources for biomaterials research through Northwestern’s medical school. The program received funding from 3M and officially launched at Northwestern in fall 2023. Approximately half of the MICRO interns are now in the program with MIT and half are with Northwestern. Wood and Garcia both participate in the program via Northwestern.

“By expanding to another school, we’ve been able to have interns work with a much broader range of research projects,” says Chazot. “It has become easier for us to place students with faculty and research that match their interests.”

Building community

The MICRO program received a Higher Education Innovation grant from the Abdul Latif Jameel World Education Lab, part of MIT Open Learning, to develop an in-person summit. In January 2024, interns visited MIT for three days of presentations, workshops, and campus tours — including a tour of the MIT.nano building — as well as various community-building activities.

“A big part of MICRO is the community,” says Chazot. “A highlight of the summit was just seeing the students come together.”

The summit also included panel discussions that allowed interns to gain insights and advice from graduate students and professionals. The graduate panel discussion included MIT graduate students Sam Figueroa (mechanical engineering), Isabella Caruso (DMSE), and Eliana Feygin (DMSE). The career panel was led by Chazot and included Jatin Patil PhD ’23, head of product at SiTration; Maureen Reitman ’90, ScD ’93, group vice president and principal engineer at Exponent; Lucas Caretta PhD ’19, assistant professor of engineering at Brown University; Raquel D’Oyen ’90, who holds a PhD from Northwestern University and is a senior engineer at Raytheon; and Ashley Kaiser MS ’19, PhD ’21, senior process engineer at 6K.

Students also had an opportunity to share their work with each other through research presentations. Their presentations covered a wide range of topics, including: developing a computer program to calculate solubility parameters for polymers used in textile manufacturing; performing a life-cycle analysis of a photonic chip and evaluating its environmental impact in comparison to a standard silicon microchip; and applying machine learning algorithms to scanning transmission electron microscopy images of CrSBr, a two-dimensional magnetic material. 

“The summit was wonderful and the best academic experience I have had as a first-year college student,” says MICRO intern Gabriella La Cour, who is pursuing a major in chemistry and dual degree biomedical engineering at Spelman College and participates in MICRO through MIT. “I got to meet so many students who were all in grades above me … and I learned a little about how to navigate college as an upperclassman.” 

“I actually have an extremely close friendship with one of the students, and we keep in touch regularly,” adds La Cour. “Professor Chazot gave valuable advice about applications and recommendation letters that will be useful when I apply to REUs [Research Experiences for Undergraduates] and graduate schools.”

Looking to the future, MICRO organizers hope to continue to grow the program’s reach.

“We would love to see other schools taking on this model,” says Sandland. “There are a lot of opportunities out there. The more departments, research groups, and mentors that get involved with this program, the more impact it can have.”

Gabrielle Wood, a junior at Howard University majoring in chemical engineering, is on a mission to improve the sustainability and life cycles of natural resources and materials. Her work in the Materials Initiative for Comprehensive Research Opportunity (MICRO) program has given her hands-on experience with many different aspects of research, including MATLAB programming, experimental design, data analysis, figure-making, and scientific writing.

Wood is also one of 10 undergraduates from 10 universities around the United States to participate in the first MICRO Summit earlier this year. The internship program, developed by the MIT Department of Materials Science and Engineering (DMSE), first launched in fall 2021. Now in its third year, the program continues to grow, providing even more opportunities for non-MIT undergraduate students — including the MICRO Summit and the program’s expansion to include Northwestern University.

“I think one of the most valuable aspects of the MICRO program is the ability to do research long term with an experienced professor in materials science and engineering,” says Wood. “My school has limited opportunities for undergraduate research in sustainable polymers, so the MICRO program allowed me to gain valuable experience in this field, which I would not otherwise have.”

Like Wood, Griheydi Garcia, a senior chemistry major at Manhattan College, values the exposure to materials science, especially since she is not able to learn as much about it at her home institution.

“I learned a lot about crystallography and defects in materials through the MICRO curriculum, especially through videos,” says Garcia. “The research itself is very valuable, as well, because we get to apply what we’ve learned through the videos in the research we do remotely.”

Expanding research opportunities

From the beginning, the MICRO program was designed as a fully remote, rigorous education and mentoring program targeted toward students from underserved backgrounds interested in pursuing graduate school in materials science or related fields. Interns are matched with faculty to work on their specific research interests.

Jessica Sandland ’99, PhD ’05, principal lecturer in DMSE and co-founder of MICRO, says that research projects for the interns are designed to be work that they can do remotely, such as developing a machine-learning algorithm or a data analysis approach.

“It’s important to note that it’s not just about what the program and faculty are bringing to the student interns,” says Sandland, a member of the MIT Digital Learning Lab, a joint program between MIT Open Learning and the Institute’s academic departments. “The students are doing real research and work, and creating things of real value. It’s very much an exchange.”

Cécile Chazot PhD ’22, now an assistant professor of materials science and engineering at Northwestern University, had helped to establish MICRO at MIT from the very beginning. Once at Northwestern, she quickly realized that expanding MICRO to Northwestern would offer even more research opportunities to interns than by relying on MIT alone — leveraging the university’s strong materials science and engineering department, as well as offering resources for biomaterials research through Northwestern’s medical school. The program received funding from 3M and officially launched at Northwestern in fall 2023. Approximately half of the MICRO interns are now in the program with MIT and half are with Northwestern. Wood and Garcia both participate in the program via Northwestern.

“By expanding to another school, we’ve been able to have interns work with a much broader range of research projects,” says Chazot. “It has become easier for us to place students with faculty and research that match their interests.”

Building community

The MICRO program received a Higher Education Innovation grant from the Abdul Latif Jameel World Education Lab, part of MIT Open Learning, to develop an in-person summit. In January 2024, interns visited MIT for three days of presentations, workshops, and campus tours — including a tour of the MIT.nano building — as well as various community-building activities.

“A big part of MICRO is the community,” says Chazot. “A highlight of the summit was just seeing the students come together.”

The summit also included panel discussions that allowed interns to gain insights and advice from graduate students and professionals. The graduate panel discussion included MIT graduate students Sam Figueroa (mechanical engineering), Isabella Caruso (DMSE), and Eliana Feygin (DMSE). The career panel was led by Chazot and included Jatin Patil PhD ’23, head of product at SiTration; Maureen Reitman ’90, ScD ’93, group vice president and principal engineer at Exponent; Lucas Caretta PhD ’19, assistant professor of engineering at Brown University; Raquel D’Oyen ’90, who holds a PhD from Northwestern University and is a senior engineer at Raytheon; and Ashley Kaiser MS ’19, PhD ’21, senior process engineer at 6K.

Students also had an opportunity to share their work with each other through research presentations. Their presentations covered a wide range of topics, including: developing a computer program to calculate solubility parameters for polymers used in textile manufacturing; performing a life-cycle analysis of a photonic chip and evaluating its environmental impact in comparison to a standard silicon microchip; and applying machine learning algorithms to scanning transmission electron microscopy images of CrSBr, a two-dimensional magnetic material. 

“The summit was wonderful and the best academic experience I have had as a first-year college student,” says MICRO intern Gabriella La Cour, who is pursuing a major in chemistry and dual degree biomedical engineering at Spelman College and participates in MICRO through MIT. “I got to meet so many students who were all in grades above me … and I learned a little about how to navigate college as an upperclassman.” 

“I actually have an extremely close friendship with one of the students, and we keep in touch regularly,” adds La Cour. “Professor Chazot gave valuable advice about applications and recommendation letters that will be useful when I apply to REUs [Research Experiences for Undergraduates] and graduate schools.”

Looking to the future, MICRO organizers hope to continue to grow the program’s reach.

“We would love to see other schools taking on this model,” says Sandland. “There are a lot of opportunities out there. The more departments, research groups, and mentors that get involved with this program, the more impact it can have.”

Gabrielle Wood, a junior at Howard University majoring in chemical engineering, is on a mission to improve the sustainability and life cycles of natural resources and materials. Her work in the Materials Initiative for Comprehensive Research Opportunity (MICRO) program has given her hands-on experience with many different aspects of research, including MATLAB programming, experimental design, data analysis, figure-making, and scientific writing.

Wood is also one of 10 undergraduates from 10 universities around the United States to participate in the first MICRO Summit earlier this year. The internship program, developed by the MIT Department of Materials Science and Engineering (DMSE), first launched in fall 2021. Now in its third year, the program continues to grow, providing even more opportunities for non-MIT undergraduate students — including the MICRO Summit and the program’s expansion to include Northwestern University.

“I think one of the most valuable aspects of the MICRO program is the ability to do research long term with an experienced professor in materials science and engineering,” says Wood. “My school has limited opportunities for undergraduate research in sustainable polymers, so the MICRO program allowed me to gain valuable experience in this field, which I would not otherwise have.”

Like Wood, Griheydi Garcia, a senior chemistry major at Manhattan College, values the exposure to materials science, especially since she is not able to learn as much about it at her home institution.

“I learned a lot about crystallography and defects in materials through the MICRO curriculum, especially through videos,” says Garcia. “The research itself is very valuable, as well, because we get to apply what we’ve learned through the videos in the research we do remotely.”

Expanding research opportunities

From the beginning, the MICRO program was designed as a fully remote, rigorous education and mentoring program targeted toward students from underserved backgrounds interested in pursuing graduate school in materials science or related fields. Interns are matched with faculty to work on their specific research interests.

Jessica Sandland ’99, PhD ’05, principal lecturer in DMSE and co-founder of MICRO, says that research projects for the interns are designed to be work that they can do remotely, such as developing a machine-learning algorithm or a data analysis approach.

“It’s important to note that it’s not just about what the program and faculty are bringing to the student interns,” says Sandland, a member of the MIT Digital Learning Lab, a joint program between MIT Open Learning and the Institute’s academic departments. “The students are doing real research and work, and creating things of real value. It’s very much an exchange.”

Cécile Chazot PhD ’22, now an assistant professor of materials science and engineering at Northwestern University, had helped to establish MICRO at MIT from the very beginning. Once at Northwestern, she quickly realized that expanding MICRO to Northwestern would offer even more research opportunities to interns than by relying on MIT alone — leveraging the university’s strong materials science and engineering department, as well as offering resources for biomaterials research through Northwestern’s medical school. The program received funding from 3M and officially launched at Northwestern in fall 2023. Approximately half of the MICRO interns are now in the program with MIT and half are with Northwestern. Wood and Garcia both participate in the program via Northwestern.

“By expanding to another school, we’ve been able to have interns work with a much broader range of research projects,” says Chazot. “It has become easier for us to place students with faculty and research that match their interests.”

Building community

The MICRO program received a Higher Education Innovation grant from the Abdul Latif Jameel World Education Lab, part of MIT Open Learning, to develop an in-person summit. In January 2024, interns visited MIT for three days of presentations, workshops, and campus tours — including a tour of the MIT.nano building — as well as various community-building activities.

“A big part of MICRO is the community,” says Chazot. “A highlight of the summit was just seeing the students come together.”

The summit also included panel discussions that allowed interns to gain insights and advice from graduate students and professionals. The graduate panel discussion included MIT graduate students Sam Figueroa (mechanical engineering), Isabella Caruso (DMSE), and Eliana Feygin (DMSE). The career panel was led by Chazot and included Jatin Patil PhD ’23, head of product at SiTration; Maureen Reitman ’90, ScD ’93, group vice president and principal engineer at Exponent; Lucas Caretta PhD ’19, assistant professor of engineering at Brown University; Raquel D’Oyen ’90, who holds a PhD from Northwestern University and is a senior engineer at Raytheon; and Ashley Kaiser MS ’19, PhD ’21, senior process engineer at 6K.

Students also had an opportunity to share their work with each other through research presentations. Their presentations covered a wide range of topics, including: developing a computer program to calculate solubility parameters for polymers used in textile manufacturing; performing a life-cycle analysis of a photonic chip and evaluating its environmental impact in comparison to a standard silicon microchip; and applying machine learning algorithms to scanning transmission electron microscopy images of CrSBr, a two-dimensional magnetic material. 

“The summit was wonderful and the best academic experience I have had as a first-year college student,” says MICRO intern Gabriella La Cour, who is pursuing a major in chemistry and dual degree biomedical engineering at Spelman College and participates in MICRO through MIT. “I got to meet so many students who were all in grades above me … and I learned a little about how to navigate college as an upperclassman.” 

“I actually have an extremely close friendship with one of the students, and we keep in touch regularly,” adds La Cour. “Professor Chazot gave valuable advice about applications and recommendation letters that will be useful when I apply to REUs [Research Experiences for Undergraduates] and graduate schools.”

Looking to the future, MICRO organizers hope to continue to grow the program’s reach.

“We would love to see other schools taking on this model,” says Sandland. “There are a lot of opportunities out there. The more departments, research groups, and mentors that get involved with this program, the more impact it can have.”

Gabrielle Wood, a junior at Howard University majoring in chemical engineering, is on a mission to improve the sustainability and life cycles of natural resources and materials. Her work in the Materials Initiative for Comprehensive Research Opportunity (MICRO) program has given her hands-on experience with many different aspects of research, including MATLAB programming, experimental design, data analysis, figure-making, and scientific writing.

Wood is also one of 10 undergraduates from 10 universities around the United States to participate in the first MICRO Summit earlier this year. The internship program, developed by the MIT Department of Materials Science and Engineering (DMSE), first launched in fall 2021. Now in its third year, the program continues to grow, providing even more opportunities for non-MIT undergraduate students — including the MICRO Summit and the program’s expansion to include Northwestern University.

“I think one of the most valuable aspects of the MICRO program is the ability to do research long term with an experienced professor in materials science and engineering,” says Wood. “My school has limited opportunities for undergraduate research in sustainable polymers, so the MICRO program allowed me to gain valuable experience in this field, which I would not otherwise have.”

Like Wood, Griheydi Garcia, a senior chemistry major at Manhattan College, values the exposure to materials science, especially since she is not able to learn as much about it at her home institution.

“I learned a lot about crystallography and defects in materials through the MICRO curriculum, especially through videos,” says Garcia. “The research itself is very valuable, as well, because we get to apply what we’ve learned through the videos in the research we do remotely.”

Expanding research opportunities

From the beginning, the MICRO program was designed as a fully remote, rigorous education and mentoring program targeted toward students from underserved backgrounds interested in pursuing graduate school in materials science or related fields. Interns are matched with faculty to work on their specific research interests.

Jessica Sandland ’99, PhD ’05, principal lecturer in DMSE and co-founder of MICRO, says that research projects for the interns are designed to be work that they can do remotely, such as developing a machine-learning algorithm or a data analysis approach.

“It’s important to note that it’s not just about what the program and faculty are bringing to the student interns,” says Sandland, a member of the MIT Digital Learning Lab, a joint program between MIT Open Learning and the Institute’s academic departments. “The students are doing real research and work, and creating things of real value. It’s very much an exchange.”

Cécile Chazot PhD ’22, now an assistant professor of materials science and engineering at Northwestern University, had helped to establish MICRO at MIT from the very beginning. Once at Northwestern, she quickly realized that expanding MICRO to Northwestern would offer even more research opportunities to interns than by relying on MIT alone — leveraging the university’s strong materials science and engineering department, as well as offering resources for biomaterials research through Northwestern’s medical school. The program received funding from 3M and officially launched at Northwestern in fall 2023. Approximately half of the MICRO interns are now in the program with MIT and half are with Northwestern. Wood and Garcia both participate in the program via Northwestern.

“By expanding to another school, we’ve been able to have interns work with a much broader range of research projects,” says Chazot. “It has become easier for us to place students with faculty and research that match their interests.”

Building community

The MICRO program received a Higher Education Innovation grant from the Abdul Latif Jameel World Education Lab, part of MIT Open Learning, to develop an in-person summit. In January 2024, interns visited MIT for three days of presentations, workshops, and campus tours — including a tour of the MIT.nano building — as well as various community-building activities.

“A big part of MICRO is the community,” says Chazot. “A highlight of the summit was just seeing the students come together.”

The summit also included panel discussions that allowed interns to gain insights and advice from graduate students and professionals. The graduate panel discussion included MIT graduate students Sam Figueroa (mechanical engineering), Isabella Caruso (DMSE), and Eliana Feygin (DMSE). The career panel was led by Chazot and included Jatin Patil PhD ’23, head of product at SiTration; Maureen Reitman ’90, ScD ’93, group vice president and principal engineer at Exponent; Lucas Caretta PhD ’19, assistant professor of engineering at Brown University; Raquel D’Oyen ’90, who holds a PhD from Northwestern University and is a senior engineer at Raytheon; and Ashley Kaiser MS ’19, PhD ’21, senior process engineer at 6K.

Students also had an opportunity to share their work with each other through research presentations. Their presentations covered a wide range of topics, including: developing a computer program to calculate solubility parameters for polymers used in textile manufacturing; performing a life-cycle analysis of a photonic chip and evaluating its environmental impact in comparison to a standard silicon microchip; and applying machine learning algorithms to scanning transmission electron microscopy images of CrSBr, a two-dimensional magnetic material. 

“The summit was wonderful and the best academic experience I have had as a first-year college student,” says MICRO intern Gabriella La Cour, who is pursuing a major in chemistry and dual degree biomedical engineering at Spelman College and participates in MICRO through MIT. “I got to meet so many students who were all in grades above me … and I learned a little about how to navigate college as an upperclassman.” 

“I actually have an extremely close friendship with one of the students, and we keep in touch regularly,” adds La Cour. “Professor Chazot gave valuable advice about applications and recommendation letters that will be useful when I apply to REUs [Research Experiences for Undergraduates] and graduate schools.”

Looking to the future, MICRO organizers hope to continue to grow the program’s reach.

“We would love to see other schools taking on this model,” says Sandland. “There are a lot of opportunities out there. The more departments, research groups, and mentors that get involved with this program, the more impact it can have.”

Want to get middle-school kids excited about science? Let them do their own experiments on MIT.nano’s state-of-the-art microscopes — with guidelines and adult supervision, of course. That was the brainchild of Carl Thrasher and Tao Cai, MIT graduate students who spearheaded the Electron Microscopy Elevating Representation and Growth in Education (EMERGE) program.

Held in November, EMERGE invited 18 eighth-grade students to the pilot event at MIT.nano, an interdisciplinary facility for nanoscale research, to get hands-on experience in microscopy and materials science.

The highlight of the two-hour workshop: Each student explored mystery samples of everyday materials using one of two scanning electron microscopes (SEMs), which scan material samples using a beam of electrons to form an image. Though highly sophisticated, the instruments generated readily understandable data — images of intricate structures in a butterfly wing or a strand of hair, for example.

The students had an immediate, tangible sense of success, says Thrasher, from MIT’s Department of Materials Science and Engineering (DMSE). He led the program along with Cai, also from DMSE, and Collette Gordon, a grad student in the Department of Chemistry.

“This experience helped build a sense of agency and autonomy around this area of science, nurturing budding self-confidence among the students,” Thrasher says. “We didn’t give the students instructions, just empowered them to solve problems. When you don’t tell them the solution, you get really surprised with what they come up with.”

Unlocking interest in the infinitesimal

The students were part of a multi-year science and engineering exploration program called MITES Saturdays, run by MIT Introduction to Technology, Engineering, and Science, or MITES. A team of volunteers was on hand to help students follow the guidance set out by Thrasher, ensuring the careful handling of the SEMs — worth roughly $500,000 each.

MITES Saturdays program administrator Lynsey Ford was thrilled to observe the students’ autonomous exploration and enthusiasm.

“Our students got to meet real scientists who listened to them, cared about the questions they were asking, and welcomed them into a world of science,” Ford says. “A supportive learning environment can be just as powerful for science discovery as a half-million-dollar microscope.”

The pilot workshop was the first step for Thrasher and his team in their goal to build EMERGE into a program with broad impact, engaging middle-to-high school students from a variety of communities.

The partnership with MITES Saturdays is crucial for this endeavor, says Thrasher, providing a platform to reach a wider audience. “Seeing students from diverse backgrounds participating in EMERGE reinforces the profound difference science education can have.”

MITES Saturdays students are high-achieving Massachusetts seventh through 12th graders from Boston, MIT’s hometown of Cambridge, and nearby Lawrence.

“The majority of students who participate in our programs would be the first person in their family to go to college. A lot of them are from families balancing some sort of financial hardship, and from populations that are historically underrepresented in STEM,” Ford says.

Experienced SEM users set up the instruments and prepared test samples so students could take turns exploring specimens such as burrs, butterfly wings, computer chips, hair, and pollen by operating the microscope to adjust magnification, focus, and stage location.

Students left the EMERGE event with copies of the electron microscope images they generated. Thrasher hopes they will use these materials in follow-up projects, ideally integrating them into existing school curricula so students can share their experiences.

EMERGE co-director Cai says students were excited with their experimentation, both in being able to access such high-end equipment and in seeing what materials like Velcro look like under an SEM (spoiler alert: it’s spaghetti).

“We definitely saw a spark,” Cai says. “The subject matter was complex, but the students always wanted to know more.” And the after-program feedback was positive, with most saying the experience was fun and challenging. The volunteers noted how engaged the students were with the SEMs and subject matter. One volunteer overheard students say, “I felt like a real scientist!”

Inspiring tomorrow’s scientists

EMERGE is based on the Scanning Electron Microscopy Educators program, a long-running STEM outreach program started in 1991 by the Air Force Research Laboratory and adopted by Michigan State University. As an Air Force captain stationed at Wright-Patterson Air Force Base in Ohio, Thrasher participated in the program as a volunteer SEM expert.

“I thought it was an incredible opportunity for young students and wanted to bring it here to MIT,” he says.

The pilot was made possible thanks to support from the MITES Saturdays team and the Graduate Materials Council (GMC), the DMSE graduate student organization. Cai and DMSE grad student Jessica Dong, who are both GMC outreach chairs, helped fund, organize, and coordinate the event.

The MITES Saturdays students included reflections on their experience with the SEMs in their final presentations at the MITES Fall Symposium in November.

“My favorite part of the semester was using the SEM as it introduced me to microscopy at the level of electrons,” said one student.

“Our students had an incredible time with the EMERGE team. We’re excited about the possibility of future partnerships with MIT.nano and other departments at MIT, giving our scholars exposure to the breadth of opportunities as future scientists,” says Eboney Hearn, MITES executive director.

With the success of the pilot, the EMERGE team is looking to offer more programs to the MITES students in the spring. Anna Osherov is excited to give students more access to the cumulative staff knowledge and cutting-edge equipment at MIT.nano, which opened in 2018. Osherov is associate director for Characterization.nano, a shared experimental facility for advanced imaging and analysis.

“Our mission is to support mature researchers — and to help inspire the future PhDs and professors who will come to MIT to learn, research, and innovate,” Osherov says. “Designing and offering such programs, aimed at fostering natural curiosity and creativity of young minds, has a tremendous long-term benefit to our society. We can raise tomorrow’s generation in a better way.”

For her part, Ford is still coasting on the students’ excitement. “They come into the program so curious and hungry for knowledge. They remind me every day how amazing the world is.”

Gabrielle Wood, a junior at Howard University majoring in chemical engineering, is on a mission to improve the sustainability and life cycles of natural resources and materials. Her work in the Materials Initiative for Comprehensive Research Opportunity (MICRO) program has given her hands-on experience with many different aspects of research, including MATLAB programming, experimental design, data analysis, figure-making, and scientific writing.

Wood is also one of 10 undergraduates from 10 universities around the United States to participate in the first MICRO Summit earlier this year. The internship program, developed by the MIT Department of Materials Science and Engineering (DMSE), first launched in fall 2021. Now in its third year, the program continues to grow, providing even more opportunities for non-MIT undergraduate students — including the MICRO Summit and the program’s expansion to include Northwestern University.

“I think one of the most valuable aspects of the MICRO program is the ability to do research long term with an experienced professor in materials science and engineering,” says Wood. “My school has limited opportunities for undergraduate research in sustainable polymers, so the MICRO program allowed me to gain valuable experience in this field, which I would not otherwise have.”

Like Wood, Griheydi Garcia, a senior chemistry major at Manhattan College, values the exposure to materials science, especially since she is not able to learn as much about it at her home institution.

“I learned a lot about crystallography and defects in materials through the MICRO curriculum, especially through videos,” says Garcia. “The research itself is very valuable, as well, because we get to apply what we’ve learned through the videos in the research we do remotely.”

Expanding research opportunities

From the beginning, the MICRO program was designed as a fully remote, rigorous education and mentoring program targeted toward students from underserved backgrounds interested in pursuing graduate school in materials science or related fields. Interns are matched with faculty to work on their specific research interests.

Jessica Sandland ’99, PhD ’05, principal lecturer in DMSE and co-founder of MICRO, says that research projects for the interns are designed to be work that they can do remotely, such as developing a machine-learning algorithm or a data analysis approach.

“It’s important to note that it’s not just about what the program and faculty are bringing to the student interns,” says Sandland, a member of the MIT Digital Learning Lab, a joint program between MIT Open Learning and the Institute’s academic departments. “The students are doing real research and work, and creating things of real value. It’s very much an exchange.”

Cécile Chazot PhD ’22, now an assistant professor of materials science and engineering at Northwestern University, had helped to establish MICRO at MIT from the very beginning. Once at Northwestern, she quickly realized that expanding MICRO to Northwestern would offer even more research opportunities to interns than by relying on MIT alone — leveraging the university’s strong materials science and engineering department, as well as offering resources for biomaterials research through Northwestern’s medical school. The program received funding from 3M and officially launched at Northwestern in fall 2023. Approximately half of the MICRO interns are now in the program with MIT and half are with Northwestern. Wood and Garcia both participate in the program via Northwestern.

“By expanding to another school, we’ve been able to have interns work with a much broader range of research projects,” says Chazot. “It has become easier for us to place students with faculty and research that match their interests.”

Building community

The MICRO program received a Higher Education Innovation grant from the Abdul Latif Jameel World Education Lab, part of MIT Open Learning, to develop an in-person summit. In January 2024, interns visited MIT for three days of presentations, workshops, and campus tours — including a tour of the MIT.nano building — as well as various community-building activities.

“A big part of MICRO is the community,” says Chazot. “A highlight of the summit was just seeing the students come together.”

The summit also included panel discussions that allowed interns to gain insights and advice from graduate students and professionals. The graduate panel discussion included MIT graduate students Sam Figueroa (mechanical engineering), Isabella Caruso (DMSE), and Eliana Feygin (DMSE). The career panel was led by Chazot and included Jatin Patil PhD ’23, head of product at SiTration; Maureen Reitman ’90, ScD ’93, group vice president and principal engineer at Exponent; Lucas Caretta PhD ’19, assistant professor of engineering at Brown University; Raquel D’Oyen ’90, who holds a PhD from Northwestern University and is a senior engineer at Raytheon; and Ashley Kaiser MS ’19, PhD ’21, senior process engineer at 6K.

Students also had an opportunity to share their work with each other through research presentations. Their presentations covered a wide range of topics, including: developing a computer program to calculate solubility parameters for polymers used in textile manufacturing; performing a life-cycle analysis of a photonic chip and evaluating its environmental impact in comparison to a standard silicon microchip; and applying machine learning algorithms to scanning transmission electron microscopy images of CrSBr, a two-dimensional magnetic material. 

“The summit was wonderful and the best academic experience I have had as a first-year college student,” says MICRO intern Gabriella La Cour, who is pursuing a major in chemistry and dual degree biomedical engineering at Spelman College and participates in MICRO through MIT. “I got to meet so many students who were all in grades above me … and I learned a little about how to navigate college as an upperclassman.” 

“I actually have an extremely close friendship with one of the students, and we keep in touch regularly,” adds La Cour. “Professor Chazot gave valuable advice about applications and recommendation letters that will be useful when I apply to REUs [Research Experiences for Undergraduates] and graduate schools.”

Looking to the future, MICRO organizers hope to continue to grow the program’s reach.

“We would love to see other schools taking on this model,” says Sandland. “There are a lot of opportunities out there. The more departments, research groups, and mentors that get involved with this program, the more impact it can have.”

Want to get middle-school kids excited about science? Let them do their own experiments on MIT.nano’s state-of-the-art microscopes — with guidelines and adult supervision, of course. That was the brainchild of Carl Thrasher and Tao Cai, MIT graduate students who spearheaded the Electron Microscopy Elevating Representation and Growth in Education (EMERGE) program.

Held in November, EMERGE invited 18 eighth-grade students to the pilot event at MIT.nano, an interdisciplinary facility for nanoscale research, to get hands-on experience in microscopy and materials science.

The highlight of the two-hour workshop: Each student explored mystery samples of everyday materials using one of two scanning electron microscopes (SEMs), which scan material samples using a beam of electrons to form an image. Though highly sophisticated, the instruments generated readily understandable data — images of intricate structures in a butterfly wing or a strand of hair, for example.

The students had an immediate, tangible sense of success, says Thrasher, from MIT’s Department of Materials Science and Engineering (DMSE). He led the program along with Cai, also from DMSE, and Collette Gordon, a grad student in the Department of Chemistry.

“This experience helped build a sense of agency and autonomy around this area of science, nurturing budding self-confidence among the students,” Thrasher says. “We didn’t give the students instructions, just empowered them to solve problems. When you don’t tell them the solution, you get really surprised with what they come up with.”

Unlocking interest in the infinitesimal

The students were part of a multi-year science and engineering exploration program called MITES Saturdays, run by MIT Introduction to Technology, Engineering, and Science, or MITES. A team of volunteers was on hand to help students follow the guidance set out by Thrasher, ensuring the careful handling of the SEMs — worth roughly $500,000 each.

MITES Saturdays program administrator Lynsey Ford was thrilled to observe the students’ autonomous exploration and enthusiasm.

“Our students got to meet real scientists who listened to them, cared about the questions they were asking, and welcomed them into a world of science,” Ford says. “A supportive learning environment can be just as powerful for science discovery as a half-million-dollar microscope.”

The pilot workshop was the first step for Thrasher and his team in their goal to build EMERGE into a program with broad impact, engaging middle-to-high school students from a variety of communities.

The partnership with MITES Saturdays is crucial for this endeavor, says Thrasher, providing a platform to reach a wider audience. “Seeing students from diverse backgrounds participating in EMERGE reinforces the profound difference science education can have.”

MITES Saturdays students are high-achieving Massachusetts seventh through 12th graders from Boston, MIT’s hometown of Cambridge, and nearby Lawrence.

“The majority of students who participate in our programs would be the first person in their family to go to college. A lot of them are from families balancing some sort of financial hardship, and from populations that are historically underrepresented in STEM,” Ford says.

Experienced SEM users set up the instruments and prepared test samples so students could take turns exploring specimens such as burrs, butterfly wings, computer chips, hair, and pollen by operating the microscope to adjust magnification, focus, and stage location.

Students left the EMERGE event with copies of the electron microscope images they generated. Thrasher hopes they will use these materials in follow-up projects, ideally integrating them into existing school curricula so students can share their experiences.

EMERGE co-director Cai says students were excited with their experimentation, both in being able to access such high-end equipment and in seeing what materials like Velcro look like under an SEM (spoiler alert: it’s spaghetti).

“We definitely saw a spark,” Cai says. “The subject matter was complex, but the students always wanted to know more.” And the after-program feedback was positive, with most saying the experience was fun and challenging. The volunteers noted how engaged the students were with the SEMs and subject matter. One volunteer overheard students say, “I felt like a real scientist!”

Inspiring tomorrow’s scientists

EMERGE is based on the Scanning Electron Microscopy Educators program, a long-running STEM outreach program started in 1991 by the Air Force Research Laboratory and adopted by Michigan State University. As an Air Force captain stationed at Wright-Patterson Air Force Base in Ohio, Thrasher participated in the program as a volunteer SEM expert.

“I thought it was an incredible opportunity for young students and wanted to bring it here to MIT,” he says.

The pilot was made possible thanks to support from the MITES Saturdays team and the Graduate Materials Council (GMC), the DMSE graduate student organization. Cai and DMSE grad student Jessica Dong, who are both GMC outreach chairs, helped fund, organize, and coordinate the event.

The MITES Saturdays students included reflections on their experience with the SEMs in their final presentations at the MITES Fall Symposium in November.

“My favorite part of the semester was using the SEM as it introduced me to microscopy at the level of electrons,” said one student.

“Our students had an incredible time with the EMERGE team. We’re excited about the possibility of future partnerships with MIT.nano and other departments at MIT, giving our scholars exposure to the breadth of opportunities as future scientists,” says Eboney Hearn, MITES executive director.

With the success of the pilot, the EMERGE team is looking to offer more programs to the MITES students in the spring. Anna Osherov is excited to give students more access to the cumulative staff knowledge and cutting-edge equipment at MIT.nano, which opened in 2018. Osherov is associate director for Characterization.nano, a shared experimental facility for advanced imaging and analysis.

“Our mission is to support mature researchers — and to help inspire the future PhDs and professors who will come to MIT to learn, research, and innovate,” Osherov says. “Designing and offering such programs, aimed at fostering natural curiosity and creativity of young minds, has a tremendous long-term benefit to our society. We can raise tomorrow’s generation in a better way.”

For her part, Ford is still coasting on the students’ excitement. “They come into the program so curious and hungry for knowledge. They remind me every day how amazing the world is.”

Gabrielle Wood, a junior at Howard University majoring in chemical engineering, is on a mission to improve the sustainability and life cycles of natural resources and materials. Her work in the Materials Initiative for Comprehensive Research Opportunity (MICRO) program has given her hands-on experience with many different aspects of research, including MATLAB programming, experimental design, data analysis, figure-making, and scientific writing.

Wood is also one of 10 undergraduates from 10 universities around the United States to participate in the first MICRO Summit earlier this year. The internship program, developed by the MIT Department of Materials Science and Engineering (DMSE), first launched in fall 2021. Now in its third year, the program continues to grow, providing even more opportunities for non-MIT undergraduate students — including the MICRO Summit and the program’s expansion to include Northwestern University.

“I think one of the most valuable aspects of the MICRO program is the ability to do research long term with an experienced professor in materials science and engineering,” says Wood. “My school has limited opportunities for undergraduate research in sustainable polymers, so the MICRO program allowed me to gain valuable experience in this field, which I would not otherwise have.”

Like Wood, Griheydi Garcia, a senior chemistry major at Manhattan College, values the exposure to materials science, especially since she is not able to learn as much about it at her home institution.

“I learned a lot about crystallography and defects in materials through the MICRO curriculum, especially through videos,” says Garcia. “The research itself is very valuable, as well, because we get to apply what we’ve learned through the videos in the research we do remotely.”

Expanding research opportunities

From the beginning, the MICRO program was designed as a fully remote, rigorous education and mentoring program targeted toward students from underserved backgrounds interested in pursuing graduate school in materials science or related fields. Interns are matched with faculty to work on their specific research interests.

Jessica Sandland ’99, PhD ’05, principal lecturer in DMSE and co-founder of MICRO, says that research projects for the interns are designed to be work that they can do remotely, such as developing a machine-learning algorithm or a data analysis approach.

“It’s important to note that it’s not just about what the program and faculty are bringing to the student interns,” says Sandland, a member of the MIT Digital Learning Lab, a joint program between MIT Open Learning and the Institute’s academic departments. “The students are doing real research and work, and creating things of real value. It’s very much an exchange.”

Cécile Chazot PhD ’22, now an assistant professor of materials science and engineering at Northwestern University, had helped to establish MICRO at MIT from the very beginning. Once at Northwestern, she quickly realized that expanding MICRO to Northwestern would offer even more research opportunities to interns than by relying on MIT alone — leveraging the university’s strong materials science and engineering department, as well as offering resources for biomaterials research through Northwestern’s medical school. The program received funding from 3M and officially launched at Northwestern in fall 2023. Approximately half of the MICRO interns are now in the program with MIT and half are with Northwestern. Wood and Garcia both participate in the program via Northwestern.

“By expanding to another school, we’ve been able to have interns work with a much broader range of research projects,” says Chazot. “It has become easier for us to place students with faculty and research that match their interests.”

Building community

The MICRO program received a Higher Education Innovation grant from the Abdul Latif Jameel World Education Lab, part of MIT Open Learning, to develop an in-person summit. In January 2024, interns visited MIT for three days of presentations, workshops, and campus tours — including a tour of the MIT.nano building — as well as various community-building activities.

“A big part of MICRO is the community,” says Chazot. “A highlight of the summit was just seeing the students come together.”

The summit also included panel discussions that allowed interns to gain insights and advice from graduate students and professionals. The graduate panel discussion included MIT graduate students Sam Figueroa (mechanical engineering), Isabella Caruso (DMSE), and Eliana Feygin (DMSE). The career panel was led by Chazot and included Jatin Patil PhD ’23, head of product at SiTration; Maureen Reitman ’90, ScD ’93, group vice president and principal engineer at Exponent; Lucas Caretta PhD ’19, assistant professor of engineering at Brown University; Raquel D’Oyen ’90, who holds a PhD from Northwestern University and is a senior engineer at Raytheon; and Ashley Kaiser MS ’19, PhD ’21, senior process engineer at 6K.

Students also had an opportunity to share their work with each other through research presentations. Their presentations covered a wide range of topics, including: developing a computer program to calculate solubility parameters for polymers used in textile manufacturing; performing a life-cycle analysis of a photonic chip and evaluating its environmental impact in comparison to a standard silicon microchip; and applying machine learning algorithms to scanning transmission electron microscopy images of CrSBr, a two-dimensional magnetic material. 

“The summit was wonderful and the best academic experience I have had as a first-year college student,” says MICRO intern Gabriella La Cour, who is pursuing a major in chemistry and dual degree biomedical engineering at Spelman College and participates in MICRO through MIT. “I got to meet so many students who were all in grades above me … and I learned a little about how to navigate college as an upperclassman.” 

“I actually have an extremely close friendship with one of the students, and we keep in touch regularly,” adds La Cour. “Professor Chazot gave valuable advice about applications and recommendation letters that will be useful when I apply to REUs [Research Experiences for Undergraduates] and graduate schools.”

Looking to the future, MICRO organizers hope to continue to grow the program’s reach.

“We would love to see other schools taking on this model,” says Sandland. “There are a lot of opportunities out there. The more departments, research groups, and mentors that get involved with this program, the more impact it can have.”

Want to get middle-school kids excited about science? Let them do their own experiments on MIT.nano’s state-of-the-art microscopes — with guidelines and adult supervision, of course. That was the brainchild of Carl Thrasher and Tao Cai, MIT graduate students who spearheaded the Electron Microscopy Elevating Representation and Growth in Education (EMERGE) program.

Held in November, EMERGE invited 18 eighth-grade students to the pilot event at MIT.nano, an interdisciplinary facility for nanoscale research, to get hands-on experience in microscopy and materials science.

The highlight of the two-hour workshop: Each student explored mystery samples of everyday materials using one of two scanning electron microscopes (SEMs), which scan material samples using a beam of electrons to form an image. Though highly sophisticated, the instruments generated readily understandable data — images of intricate structures in a butterfly wing or a strand of hair, for example.

The students had an immediate, tangible sense of success, says Thrasher, from MIT’s Department of Materials Science and Engineering (DMSE). He led the program along with Cai, also from DMSE, and Collette Gordon, a grad student in the Department of Chemistry.

“This experience helped build a sense of agency and autonomy around this area of science, nurturing budding self-confidence among the students,” Thrasher says. “We didn’t give the students instructions, just empowered them to solve problems. When you don’t tell them the solution, you get really surprised with what they come up with.”

Unlocking interest in the infinitesimal

The students were part of a multi-year science and engineering exploration program called MITES Saturdays, run by MIT Introduction to Technology, Engineering, and Science, or MITES. A team of volunteers was on hand to help students follow the guidance set out by Thrasher, ensuring the careful handling of the SEMs — worth roughly $500,000 each.

MITES Saturdays program administrator Lynsey Ford was thrilled to observe the students’ autonomous exploration and enthusiasm.

“Our students got to meet real scientists who listened to them, cared about the questions they were asking, and welcomed them into a world of science,” Ford says. “A supportive learning environment can be just as powerful for science discovery as a half-million-dollar microscope.”

The pilot workshop was the first step for Thrasher and his team in their goal to build EMERGE into a program with broad impact, engaging middle-to-high school students from a variety of communities.

The partnership with MITES Saturdays is crucial for this endeavor, says Thrasher, providing a platform to reach a wider audience. “Seeing students from diverse backgrounds participating in EMERGE reinforces the profound difference science education can have.”

MITES Saturdays students are high-achieving Massachusetts seventh through 12th graders from Boston, MIT’s hometown of Cambridge, and nearby Lawrence.

“The majority of students who participate in our programs would be the first person in their family to go to college. A lot of them are from families balancing some sort of financial hardship, and from populations that are historically underrepresented in STEM,” Ford says.

Experienced SEM users set up the instruments and prepared test samples so students could take turns exploring specimens such as burrs, butterfly wings, computer chips, hair, and pollen by operating the microscope to adjust magnification, focus, and stage location.

Students left the EMERGE event with copies of the electron microscope images they generated. Thrasher hopes they will use these materials in follow-up projects, ideally integrating them into existing school curricula so students can share their experiences.

EMERGE co-director Cai says students were excited with their experimentation, both in being able to access such high-end equipment and in seeing what materials like Velcro look like under an SEM (spoiler alert: it’s spaghetti).

“We definitely saw a spark,” Cai says. “The subject matter was complex, but the students always wanted to know more.” And the after-program feedback was positive, with most saying the experience was fun and challenging. The volunteers noted how engaged the students were with the SEMs and subject matter. One volunteer overheard students say, “I felt like a real scientist!”

Inspiring tomorrow’s scientists

EMERGE is based on the Scanning Electron Microscopy Educators program, a long-running STEM outreach program started in 1991 by the Air Force Research Laboratory and adopted by Michigan State University. As an Air Force captain stationed at Wright-Patterson Air Force Base in Ohio, Thrasher participated in the program as a volunteer SEM expert.

“I thought it was an incredible opportunity for young students and wanted to bring it here to MIT,” he says.

The pilot was made possible thanks to support from the MITES Saturdays team and the Graduate Materials Council (GMC), the DMSE graduate student organization. Cai and DMSE grad student Jessica Dong, who are both GMC outreach chairs, helped fund, organize, and coordinate the event.

The MITES Saturdays students included reflections on their experience with the SEMs in their final presentations at the MITES Fall Symposium in November.

“My favorite part of the semester was using the SEM as it introduced me to microscopy at the level of electrons,” said one student.

“Our students had an incredible time with the EMERGE team. We’re excited about the possibility of future partnerships with MIT.nano and other departments at MIT, giving our scholars exposure to the breadth of opportunities as future scientists,” says Eboney Hearn, MITES executive director.

With the success of the pilot, the EMERGE team is looking to offer more programs to the MITES students in the spring. Anna Osherov is excited to give students more access to the cumulative staff knowledge and cutting-edge equipment at MIT.nano, which opened in 2018. Osherov is associate director for Characterization.nano, a shared experimental facility for advanced imaging and analysis.

“Our mission is to support mature researchers — and to help inspire the future PhDs and professors who will come to MIT to learn, research, and innovate,” Osherov says. “Designing and offering such programs, aimed at fostering natural curiosity and creativity of young minds, has a tremendous long-term benefit to our society. We can raise tomorrow’s generation in a better way.”

For her part, Ford is still coasting on the students’ excitement. “They come into the program so curious and hungry for knowledge. They remind me every day how amazing the world is.”

Gabrielle Wood, a junior at Howard University majoring in chemical engineering, is on a mission to improve the sustainability and life cycles of natural resources and materials. Her work in the Materials Initiative for Comprehensive Research Opportunity (MICRO) program has given her hands-on experience with many different aspects of research, including MATLAB programming, experimental design, data analysis, figure-making, and scientific writing.

Wood is also one of 10 undergraduates from 10 universities around the United States to participate in the first MICRO Summit earlier this year. The internship program, developed by the MIT Department of Materials Science and Engineering (DMSE), first launched in fall 2021. Now in its third year, the program continues to grow, providing even more opportunities for non-MIT undergraduate students — including the MICRO Summit and the program’s expansion to include Northwestern University.

“I think one of the most valuable aspects of the MICRO program is the ability to do research long term with an experienced professor in materials science and engineering,” says Wood. “My school has limited opportunities for undergraduate research in sustainable polymers, so the MICRO program allowed me to gain valuable experience in this field, which I would not otherwise have.”

Like Wood, Griheydi Garcia, a senior chemistry major at Manhattan College, values the exposure to materials science, especially since she is not able to learn as much about it at her home institution.

“I learned a lot about crystallography and defects in materials through the MICRO curriculum, especially through videos,” says Garcia. “The research itself is very valuable, as well, because we get to apply what we’ve learned through the videos in the research we do remotely.”

Expanding research opportunities

From the beginning, the MICRO program was designed as a fully remote, rigorous education and mentoring program targeted toward students from underserved backgrounds interested in pursuing graduate school in materials science or related fields. Interns are matched with faculty to work on their specific research interests.

Jessica Sandland ’99, PhD ’05, principal lecturer in DMSE and co-founder of MICRO, says that research projects for the interns are designed to be work that they can do remotely, such as developing a machine-learning algorithm or a data analysis approach.

“It’s important to note that it’s not just about what the program and faculty are bringing to the student interns,” says Sandland, a member of the MIT Digital Learning Lab, a joint program between MIT Open Learning and the Institute’s academic departments. “The students are doing real research and work, and creating things of real value. It’s very much an exchange.”

Cécile Chazot PhD ’22, now an assistant professor of materials science and engineering at Northwestern University, had helped to establish MICRO at MIT from the very beginning. Once at Northwestern, she quickly realized that expanding MICRO to Northwestern would offer even more research opportunities to interns than by relying on MIT alone — leveraging the university’s strong materials science and engineering department, as well as offering resources for biomaterials research through Northwestern’s medical school. The program received funding from 3M and officially launched at Northwestern in fall 2023. Approximately half of the MICRO interns are now in the program with MIT and half are with Northwestern. Wood and Garcia both participate in the program via Northwestern.

“By expanding to another school, we’ve been able to have interns work with a much broader range of research projects,” says Chazot. “It has become easier for us to place students with faculty and research that match their interests.”

Building community

The MICRO program received a Higher Education Innovation grant from the Abdul Latif Jameel World Education Lab, part of MIT Open Learning, to develop an in-person summit. In January 2024, interns visited MIT for three days of presentations, workshops, and campus tours — including a tour of the MIT.nano building — as well as various community-building activities.

“A big part of MICRO is the community,” says Chazot. “A highlight of the summit was just seeing the students come together.”

The summit also included panel discussions that allowed interns to gain insights and advice from graduate students and professionals. The graduate panel discussion included MIT graduate students Sam Figueroa (mechanical engineering), Isabella Caruso (DMSE), and Eliana Feygin (DMSE). The career panel was led by Chazot and included Jatin Patil PhD ’23, head of product at SiTration; Maureen Reitman ’90, ScD ’93, group vice president and principal engineer at Exponent; Lucas Caretta PhD ’19, assistant professor of engineering at Brown University; Raquel D’Oyen ’90, who holds a PhD from Northwestern University and is a senior engineer at Raytheon; and Ashley Kaiser MS ’19, PhD ’21, senior process engineer at 6K.

Students also had an opportunity to share their work with each other through research presentations. Their presentations covered a wide range of topics, including: developing a computer program to calculate solubility parameters for polymers used in textile manufacturing; performing a life-cycle analysis of a photonic chip and evaluating its environmental impact in comparison to a standard silicon microchip; and applying machine learning algorithms to scanning transmission electron microscopy images of CrSBr, a two-dimensional magnetic material. 

“The summit was wonderful and the best academic experience I have had as a first-year college student,” says MICRO intern Gabriella La Cour, who is pursuing a major in chemistry and dual degree biomedical engineering at Spelman College and participates in MICRO through MIT. “I got to meet so many students who were all in grades above me … and I learned a little about how to navigate college as an upperclassman.” 

“I actually have an extremely close friendship with one of the students, and we keep in touch regularly,” adds La Cour. “Professor Chazot gave valuable advice about applications and recommendation letters that will be useful when I apply to REUs [Research Experiences for Undergraduates] and graduate schools.”

Looking to the future, MICRO organizers hope to continue to grow the program’s reach.

“We would love to see other schools taking on this model,” says Sandland. “There are a lot of opportunities out there. The more departments, research groups, and mentors that get involved with this program, the more impact it can have.”

Want to get middle-school kids excited about science? Let them do their own experiments on MIT.nano’s state-of-the-art microscopes — with guidelines and adult supervision, of course. That was the brainchild of Carl Thrasher and Tao Cai, MIT graduate students who spearheaded the Electron Microscopy Elevating Representation and Growth in Education (EMERGE) program.

Held in November, EMERGE invited 18 eighth-grade students to the pilot event at MIT.nano, an interdisciplinary facility for nanoscale research, to get hands-on experience in microscopy and materials science.

The highlight of the two-hour workshop: Each student explored mystery samples of everyday materials using one of two scanning electron microscopes (SEMs), which scan material samples using a beam of electrons to form an image. Though highly sophisticated, the instruments generated readily understandable data — images of intricate structures in a butterfly wing or a strand of hair, for example.

The students had an immediate, tangible sense of success, says Thrasher, from MIT’s Department of Materials Science and Engineering (DMSE). He led the program along with Cai, also from DMSE, and Collette Gordon, a grad student in the Department of Chemistry.

“This experience helped build a sense of agency and autonomy around this area of science, nurturing budding self-confidence among the students,” Thrasher says. “We didn’t give the students instructions, just empowered them to solve problems. When you don’t tell them the solution, you get really surprised with what they come up with.”

Unlocking interest in the infinitesimal

The students were part of a multi-year science and engineering exploration program called MITES Saturdays, run by MIT Introduction to Technology, Engineering, and Science, or MITES. A team of volunteers was on hand to help students follow the guidance set out by Thrasher, ensuring the careful handling of the SEMs — worth roughly $500,000 each.

MITES Saturdays program administrator Lynsey Ford was thrilled to observe the students’ autonomous exploration and enthusiasm.

“Our students got to meet real scientists who listened to them, cared about the questions they were asking, and welcomed them into a world of science,” Ford says. “A supportive learning environment can be just as powerful for science discovery as a half-million-dollar microscope.”

The pilot workshop was the first step for Thrasher and his team in their goal to build EMERGE into a program with broad impact, engaging middle-to-high school students from a variety of communities.

The partnership with MITES Saturdays is crucial for this endeavor, says Thrasher, providing a platform to reach a wider audience. “Seeing students from diverse backgrounds participating in EMERGE reinforces the profound difference science education can have.”

MITES Saturdays students are high-achieving Massachusetts seventh through 12th graders from Boston, MIT’s hometown of Cambridge, and nearby Lawrence.

“The majority of students who participate in our programs would be the first person in their family to go to college. A lot of them are from families balancing some sort of financial hardship, and from populations that are historically underrepresented in STEM,” Ford says.

Experienced SEM users set up the instruments and prepared test samples so students could take turns exploring specimens such as burrs, butterfly wings, computer chips, hair, and pollen by operating the microscope to adjust magnification, focus, and stage location.

Students left the EMERGE event with copies of the electron microscope images they generated. Thrasher hopes they will use these materials in follow-up projects, ideally integrating them into existing school curricula so students can share their experiences.

EMERGE co-director Cai says students were excited with their experimentation, both in being able to access such high-end equipment and in seeing what materials like Velcro look like under an SEM (spoiler alert: it’s spaghetti).

“We definitely saw a spark,” Cai says. “The subject matter was complex, but the students always wanted to know more.” And the after-program feedback was positive, with most saying the experience was fun and challenging. The volunteers noted how engaged the students were with the SEMs and subject matter. One volunteer overheard students say, “I felt like a real scientist!”

Inspiring tomorrow’s scientists

EMERGE is based on the Scanning Electron Microscopy Educators program, a long-running STEM outreach program started in 1991 by the Air Force Research Laboratory and adopted by Michigan State University. As an Air Force captain stationed at Wright-Patterson Air Force Base in Ohio, Thrasher participated in the program as a volunteer SEM expert.

“I thought it was an incredible opportunity for young students and wanted to bring it here to MIT,” he says.

The pilot was made possible thanks to support from the MITES Saturdays team and the Graduate Materials Council (GMC), the DMSE graduate student organization. Cai and DMSE grad student Jessica Dong, who are both GMC outreach chairs, helped fund, organize, and coordinate the event.

The MITES Saturdays students included reflections on their experience with the SEMs in their final presentations at the MITES Fall Symposium in November.

“My favorite part of the semester was using the SEM as it introduced me to microscopy at the level of electrons,” said one student.

“Our students had an incredible time with the EMERGE team. We’re excited about the possibility of future partnerships with MIT.nano and other departments at MIT, giving our scholars exposure to the breadth of opportunities as future scientists,” says Eboney Hearn, MITES executive director.

With the success of the pilot, the EMERGE team is looking to offer more programs to the MITES students in the spring. Anna Osherov is excited to give students more access to the cumulative staff knowledge and cutting-edge equipment at MIT.nano, which opened in 2018. Osherov is associate director for Characterization.nano, a shared experimental facility for advanced imaging and analysis.

“Our mission is to support mature researchers — and to help inspire the future PhDs and professors who will come to MIT to learn, research, and innovate,” Osherov says. “Designing and offering such programs, aimed at fostering natural curiosity and creativity of young minds, has a tremendous long-term benefit to our society. We can raise tomorrow’s generation in a better way.”

For her part, Ford is still coasting on the students’ excitement. “They come into the program so curious and hungry for knowledge. They remind me every day how amazing the world is.”

“How do we get to making nanomaterials that haven’t been evolved before?” asked Angela Belcher at the 2023 Mildred S. Dresselhaus Lecture at MIT on Nov. 20. “We can use elements that biology has already given us.”

The combined in-person and virtual audience of over 300 was treated to a light-up, 3D model of M13 bacteriophage, a virus that only infects bacteria, complete with a pull-out strand of DNA. Belcher used the feather-boa-like model to show how her research group modifies the M13’s genes to add new DNA and peptide sequences to template inorganic materials.

“I love controlling materials at the nanoscale using biology,” said Belcher, the James Mason Crafts Professor of Biological Engineering, materials science professor, and of the Koch Institute of Integrative Cancer Research at MIT. “We all know if you control materials at the nanoscale and you can start to tune them, then you can have all kinds of different applications.” And the opportunities are indeed vast — from building batteries, fuel cells, and solar cells to carbon sequestration and storage, environmental remediation, catalysis, and medical diagnostics and imaging.

Belcher sprinkled her talk with models and props, lined up on a table at the front of the 10-250 lecture hall, to demonstrate a wide variety of concepts and projects made possible by the intersection of biology and nanotechnology.

Energy storage and environment

“How do you go from a DNA sequence to a functioning battery?” posed Belcher. Grabbing a model of a large carbon nanotube, she explained how her group engineered a phage to pick up carbon nanotubes that would wind all the way around the virus and then fill in with different cathode or anode materials to make nanowires for battery electrodes.

How about using the M13 bacteriophage to improve the environment? Belcher referred to a project by former student Geran Zhang PhD ’19 that proved the virus can be modified for this context, too. He used the phage to template high-surface-area, carbon-based materials that can grab small molecules and break them down, Belcher said, opening a realm of possibilities from cleaning up rivers to developing chemical warfare agents to combating smog.

Belcher’s lab worked with the U.S. Army to produce protective clothing and masks made of these carbon-based virus nanofibers. “We went from five liters in our lab to a thousand liters, then 10,000 liters in the army labs where we’re able to make kilograms of the material,” Belcher said, stressing the importance of being able to test and prototype at scale.

Imaging tools and therapeutics in cancer

In the area of biomedical imaging, Belcher explained, a lot less is known in near-infrared imaging — imaging in wavelengths above 1,000 nanometers — than other imaging techniques, yet with near-infrared scientists can see much deeper inside the body. Belcher’s lab built their own systems to image at these wavelengths. The third generation of this system provides real-time, sub-millimeter optical imaging for guided surgery.

Working with Sangeeta Bhatia, the John J. and Dorothy Wilson Professor of Engineering, Belcher used carbon nanotubes to build imaging tools that find tiny tumors during surgery that doctors otherwise would not be able to see. The tool is actually a virus engineered to carry with it a fluorescent, single-walled carbon nanotube as it seeks out the tumors.

Nearing the end of her talk, Belcher presented a goal: to develop an accessible detection and diagnostic technology for ovarian cancer in five to 10 years.

“We think that we can do it,” Belcher said. She described her students’ work developing a way to scan an entire fallopian tube, as opposed to just one small portion, to find pre-cancer lesions, and talked about the team of MIT faculty, doctors, and researchers working collectively toward this goal.

“Part of the secret of life and the meaning of life is helping other people enjoy the passage of time,” said Belcher in her closing remarks. “I think that we can all do that by working to solve some of the biggest issues on the planet, including helping to diagnose and treat ovarian cancer early so people have more time to spend with their family.”

Honoring Mildred S. Dresselhaus

Belcher was the fifth speaker to deliver the Dresselhaus Lecture, an annual event organized by MIT.nano to honor the late MIT physics and electrical engineering Institute Professor Mildred Dresselhaus. The lecture features a speaker from anywhere in the world whose leadership and impact echo Dresselhaus’s life, accomplishments, and values.

“Millie was and is a huge hero of mine,” said Belcher. “Giving a lecture in Millie’s name is just the greatest honor.”

Belcher dedicated the talk to Dresselhaus, whom she described with an array of accolades — a trailblazer, a genius, an amazing mentor, teacher, and inventor. “Just knowing her was such a privilege,” she said.

Belcher also dedicated her talk to her own grandmother and mother, both of whom passed away from cancer, as well as late MIT professors Susan Lindquist and Angelika Amon, who both died of ovarian cancer.

“I’ve been so fortunate to work with just the most talented and dedicated graduate students, undergraduate students, postdocs, and researchers,” concluded Belcher. “It has been a pure joy to be in partnership with all of you to solve these very daunting problems.”

Gabrielle Wood, a junior at Howard University majoring in chemical engineering, is on a mission to improve the sustainability and life cycles of natural resources and materials. Her work in the Materials Initiative for Comprehensive Research Opportunity (MICRO) program has given her hands-on experience with many different aspects of research, including MATLAB programming, experimental design, data analysis, figure-making, and scientific writing.

Wood is also one of 10 undergraduates from 10 universities around the United States to participate in the first MICRO Summit earlier this year. The internship program, developed by the MIT Department of Materials Science and Engineering (DMSE), first launched in fall 2021. Now in its third year, the program continues to grow, providing even more opportunities for non-MIT undergraduate students — including the MICRO Summit and the program’s expansion to include Northwestern University.

“I think one of the most valuable aspects of the MICRO program is the ability to do research long term with an experienced professor in materials science and engineering,” says Wood. “My school has limited opportunities for undergraduate research in sustainable polymers, so the MICRO program allowed me to gain valuable experience in this field, which I would not otherwise have.”

Like Wood, Griheydi Garcia, a senior chemistry major at Manhattan College, values the exposure to materials science, especially since she is not able to learn as much about it at her home institution.

“I learned a lot about crystallography and defects in materials through the MICRO curriculum, especially through videos,” says Garcia. “The research itself is very valuable, as well, because we get to apply what we’ve learned through the videos in the research we do remotely.”

Expanding research opportunities

From the beginning, the MICRO program was designed as a fully remote, rigorous education and mentoring program targeted toward students from underserved backgrounds interested in pursuing graduate school in materials science or related fields. Interns are matched with faculty to work on their specific research interests.

Jessica Sandland ’99, PhD ’05, principal lecturer in DMSE and co-founder of MICRO, says that research projects for the interns are designed to be work that they can do remotely, such as developing a machine-learning algorithm or a data analysis approach.

“It’s important to note that it’s not just about what the program and faculty are bringing to the student interns,” says Sandland, a member of the MIT Digital Learning Lab, a joint program between MIT Open Learning and the Institute’s academic departments. “The students are doing real research and work, and creating things of real value. It’s very much an exchange.”

Cécile Chazot PhD ’22, now an assistant professor of materials science and engineering at Northwestern University, had helped to establish MICRO at MIT from the very beginning. Once at Northwestern, she quickly realized that expanding MICRO to Northwestern would offer even more research opportunities to interns than by relying on MIT alone — leveraging the university’s strong materials science and engineering department, as well as offering resources for biomaterials research through Northwestern’s medical school. The program received funding from 3M and officially launched at Northwestern in fall 2023. Approximately half of the MICRO interns are now in the program with MIT and half are with Northwestern. Wood and Garcia both participate in the program via Northwestern.

“By expanding to another school, we’ve been able to have interns work with a much broader range of research projects,” says Chazot. “It has become easier for us to place students with faculty and research that match their interests.”

Building community

The MICRO program received a Higher Education Innovation grant from the Abdul Latif Jameel World Education Lab, part of MIT Open Learning, to develop an in-person summit. In January 2024, interns visited MIT for three days of presentations, workshops, and campus tours — including a tour of the MIT.nano building — as well as various community-building activities.

“A big part of MICRO is the community,” says Chazot. “A highlight of the summit was just seeing the students come together.”

The summit also included panel discussions that allowed interns to gain insights and advice from graduate students and professionals. The graduate panel discussion included MIT graduate students Sam Figueroa (mechanical engineering), Isabella Caruso (DMSE), and Eliana Feygin (DMSE). The career panel was led by Chazot and included Jatin Patil PhD ’23, head of product at SiTration; Maureen Reitman ’90, ScD ’93, group vice president and principal engineer at Exponent; Lucas Caretta PhD ’19, assistant professor of engineering at Brown University; Raquel D’Oyen ’90, who holds a PhD from Northwestern University and is a senior engineer at Raytheon; and Ashley Kaiser MS ’19, PhD ’21, senior process engineer at 6K.

Students also had an opportunity to share their work with each other through research presentations. Their presentations covered a wide range of topics, including: developing a computer program to calculate solubility parameters for polymers used in textile manufacturing; performing a life-cycle analysis of a photonic chip and evaluating its environmental impact in comparison to a standard silicon microchip; and applying machine learning algorithms to scanning transmission electron microscopy images of CrSBr, a two-dimensional magnetic material. 

“The summit was wonderful and the best academic experience I have had as a first-year college student,” says MICRO intern Gabriella La Cour, who is pursuing a major in chemistry and dual degree biomedical engineering at Spelman College and participates in MICRO through MIT. “I got to meet so many students who were all in grades above me … and I learned a little about how to navigate college as an upperclassman.” 

“I actually have an extremely close friendship with one of the students, and we keep in touch regularly,” adds La Cour. “Professor Chazot gave valuable advice about applications and recommendation letters that will be useful when I apply to REUs [Research Experiences for Undergraduates] and graduate schools.”

Looking to the future, MICRO organizers hope to continue to grow the program’s reach.

“We would love to see other schools taking on this model,” says Sandland. “There are a lot of opportunities out there. The more departments, research groups, and mentors that get involved with this program, the more impact it can have.”

Want to get middle-school kids excited about science? Let them do their own experiments on MIT.nano’s state-of-the-art microscopes — with guidelines and adult supervision, of course. That was the brainchild of Carl Thrasher and Tao Cai, MIT graduate students who spearheaded the Electron Microscopy Elevating Representation and Growth in Education (EMERGE) program.

Held in November, EMERGE invited 18 eighth-grade students to the pilot event at MIT.nano, an interdisciplinary facility for nanoscale research, to get hands-on experience in microscopy and materials science.

The highlight of the two-hour workshop: Each student explored mystery samples of everyday materials using one of two scanning electron microscopes (SEMs), which scan material samples using a beam of electrons to form an image. Though highly sophisticated, the instruments generated readily understandable data — images of intricate structures in a butterfly wing or a strand of hair, for example.

The students had an immediate, tangible sense of success, says Thrasher, from MIT’s Department of Materials Science and Engineering (DMSE). He led the program along with Cai, also from DMSE, and Collette Gordon, a grad student in the Department of Chemistry.

“This experience helped build a sense of agency and autonomy around this area of science, nurturing budding self-confidence among the students,” Thrasher says. “We didn’t give the students instructions, just empowered them to solve problems. When you don’t tell them the solution, you get really surprised with what they come up with.”

Unlocking interest in the infinitesimal

The students were part of a multi-year science and engineering exploration program called MITES Saturdays, run by MIT Introduction to Technology, Engineering, and Science, or MITES. A team of volunteers was on hand to help students follow the guidance set out by Thrasher, ensuring the careful handling of the SEMs — worth roughly $500,000 each.

MITES Saturdays program administrator Lynsey Ford was thrilled to observe the students’ autonomous exploration and enthusiasm.

“Our students got to meet real scientists who listened to them, cared about the questions they were asking, and welcomed them into a world of science,” Ford says. “A supportive learning environment can be just as powerful for science discovery as a half-million-dollar microscope.”

The pilot workshop was the first step for Thrasher and his team in their goal to build EMERGE into a program with broad impact, engaging middle-to-high school students from a variety of communities.

The partnership with MITES Saturdays is crucial for this endeavor, says Thrasher, providing a platform to reach a wider audience. “Seeing students from diverse backgrounds participating in EMERGE reinforces the profound difference science education can have.”

MITES Saturdays students are high-achieving Massachusetts seventh through 12th graders from Boston, MIT’s hometown of Cambridge, and nearby Lawrence.

“The majority of students who participate in our programs would be the first person in their family to go to college. A lot of them are from families balancing some sort of financial hardship, and from populations that are historically underrepresented in STEM,” Ford says.

Experienced SEM users set up the instruments and prepared test samples so students could take turns exploring specimens such as burrs, butterfly wings, computer chips, hair, and pollen by operating the microscope to adjust magnification, focus, and stage location.

Students left the EMERGE event with copies of the electron microscope images they generated. Thrasher hopes they will use these materials in follow-up projects, ideally integrating them into existing school curricula so students can share their experiences.

EMERGE co-director Cai says students were excited with their experimentation, both in being able to access such high-end equipment and in seeing what materials like Velcro look like under an SEM (spoiler alert: it’s spaghetti).

“We definitely saw a spark,” Cai says. “The subject matter was complex, but the students always wanted to know more.” And the after-program feedback was positive, with most saying the experience was fun and challenging. The volunteers noted how engaged the students were with the SEMs and subject matter. One volunteer overheard students say, “I felt like a real scientist!”

Inspiring tomorrow’s scientists

EMERGE is based on the Scanning Electron Microscopy Educators program, a long-running STEM outreach program started in 1991 by the Air Force Research Laboratory and adopted by Michigan State University. As an Air Force captain stationed at Wright-Patterson Air Force Base in Ohio, Thrasher participated in the program as a volunteer SEM expert.

“I thought it was an incredible opportunity for young students and wanted to bring it here to MIT,” he says.

The pilot was made possible thanks to support from the MITES Saturdays team and the Graduate Materials Council (GMC), the DMSE graduate student organization. Cai and DMSE grad student Jessica Dong, who are both GMC outreach chairs, helped fund, organize, and coordinate the event.

The MITES Saturdays students included reflections on their experience with the SEMs in their final presentations at the MITES Fall Symposium in November.

“My favorite part of the semester was using the SEM as it introduced me to microscopy at the level of electrons,” said one student.

“Our students had an incredible time with the EMERGE team. We’re excited about the possibility of future partnerships with MIT.nano and other departments at MIT, giving our scholars exposure to the breadth of opportunities as future scientists,” says Eboney Hearn, MITES executive director.

With the success of the pilot, the EMERGE team is looking to offer more programs to the MITES students in the spring. Anna Osherov is excited to give students more access to the cumulative staff knowledge and cutting-edge equipment at MIT.nano, which opened in 2018. Osherov is associate director for Characterization.nano, a shared experimental facility for advanced imaging and analysis.

“Our mission is to support mature researchers — and to help inspire the future PhDs and professors who will come to MIT to learn, research, and innovate,” Osherov says. “Designing and offering such programs, aimed at fostering natural curiosity and creativity of young minds, has a tremendous long-term benefit to our society. We can raise tomorrow’s generation in a better way.”

For her part, Ford is still coasting on the students’ excitement. “They come into the program so curious and hungry for knowledge. They remind me every day how amazing the world is.”

“How do we get to making nanomaterials that haven’t been evolved before?” asked Angela Belcher at the 2023 Mildred S. Dresselhaus Lecture at MIT on Nov. 20. “We can use elements that biology has already given us.”

The combined in-person and virtual audience of over 300 was treated to a light-up, 3D model of M13 bacteriophage, a virus that only infects bacteria, complete with a pull-out strand of DNA. Belcher used the feather-boa-like model to show how her research group modifies the M13’s genes to add new DNA and peptide sequences to template inorganic materials.

“I love controlling materials at the nanoscale using biology,” said Belcher, the James Mason Crafts Professor of Biological Engineering, materials science professor, and of the Koch Institute of Integrative Cancer Research at MIT. “We all know if you control materials at the nanoscale and you can start to tune them, then you can have all kinds of different applications.” And the opportunities are indeed vast — from building batteries, fuel cells, and solar cells to carbon sequestration and storage, environmental remediation, catalysis, and medical diagnostics and imaging.

Belcher sprinkled her talk with models and props, lined up on a table at the front of the 10-250 lecture hall, to demonstrate a wide variety of concepts and projects made possible by the intersection of biology and nanotechnology.

Energy storage and environment

“How do you go from a DNA sequence to a functioning battery?” posed Belcher. Grabbing a model of a large carbon nanotube, she explained how her group engineered a phage to pick up carbon nanotubes that would wind all the way around the virus and then fill in with different cathode or anode materials to make nanowires for battery electrodes.

How about using the M13 bacteriophage to improve the environment? Belcher referred to a project by former student Geran Zhang PhD ’19 that proved the virus can be modified for this context, too. He used the phage to template high-surface-area, carbon-based materials that can grab small molecules and break them down, Belcher said, opening a realm of possibilities from cleaning up rivers to developing chemical warfare agents to combating smog.

Belcher’s lab worked with the U.S. Army to produce protective clothing and masks made of these carbon-based virus nanofibers. “We went from five liters in our lab to a thousand liters, then 10,000 liters in the army labs where we’re able to make kilograms of the material,” Belcher said, stressing the importance of being able to test and prototype at scale.

Imaging tools and therapeutics in cancer

In the area of biomedical imaging, Belcher explained, a lot less is known in near-infrared imaging — imaging in wavelengths above 1,000 nanometers — than other imaging techniques, yet with near-infrared scientists can see much deeper inside the body. Belcher’s lab built their own systems to image at these wavelengths. The third generation of this system provides real-time, sub-millimeter optical imaging for guided surgery.

Working with Sangeeta Bhatia, the John J. and Dorothy Wilson Professor of Engineering, Belcher used carbon nanotubes to build imaging tools that find tiny tumors during surgery that doctors otherwise would not be able to see. The tool is actually a virus engineered to carry with it a fluorescent, single-walled carbon nanotube as it seeks out the tumors.

Nearing the end of her talk, Belcher presented a goal: to develop an accessible detection and diagnostic technology for ovarian cancer in five to 10 years.

“We think that we can do it,” Belcher said. She described her students’ work developing a way to scan an entire fallopian tube, as opposed to just one small portion, to find pre-cancer lesions, and talked about the team of MIT faculty, doctors, and researchers working collectively toward this goal.

“Part of the secret of life and the meaning of life is helping other people enjoy the passage of time,” said Belcher in her closing remarks. “I think that we can all do that by working to solve some of the biggest issues on the planet, including helping to diagnose and treat ovarian cancer early so people have more time to spend with their family.”

Honoring Mildred S. Dresselhaus

Belcher was the fifth speaker to deliver the Dresselhaus Lecture, an annual event organized by MIT.nano to honor the late MIT physics and electrical engineering Institute Professor Mildred Dresselhaus. The lecture features a speaker from anywhere in the world whose leadership and impact echo Dresselhaus’s life, accomplishments, and values.

“Millie was and is a huge hero of mine,” said Belcher. “Giving a lecture in Millie’s name is just the greatest honor.”

Belcher dedicated the talk to Dresselhaus, whom she described with an array of accolades — a trailblazer, a genius, an amazing mentor, teacher, and inventor. “Just knowing her was such a privilege,” she said.

Belcher also dedicated her talk to her own grandmother and mother, both of whom passed away from cancer, as well as late MIT professors Susan Lindquist and Angelika Amon, who both died of ovarian cancer.

“I’ve been so fortunate to work with just the most talented and dedicated graduate students, undergraduate students, postdocs, and researchers,” concluded Belcher. “It has been a pure joy to be in partnership with all of you to solve these very daunting problems.”

Gabrielle Wood, a junior at Howard University majoring in chemical engineering, is on a mission to improve the sustainability and life cycles of natural resources and materials. Her work in the Materials Initiative for Comprehensive Research Opportunity (MICRO) program has given her hands-on experience with many different aspects of research, including MATLAB programming, experimental design, data analysis, figure-making, and scientific writing.

Wood is also one of 10 undergraduates from 10 universities around the United States to participate in the first MICRO Summit earlier this year. The internship program, developed by the MIT Department of Materials Science and Engineering (DMSE), first launched in fall 2021. Now in its third year, the program continues to grow, providing even more opportunities for non-MIT undergraduate students — including the MICRO Summit and the program’s expansion to include Northwestern University.

“I think one of the most valuable aspects of the MICRO program is the ability to do research long term with an experienced professor in materials science and engineering,” says Wood. “My school has limited opportunities for undergraduate research in sustainable polymers, so the MICRO program allowed me to gain valuable experience in this field, which I would not otherwise have.”

Like Wood, Griheydi Garcia, a senior chemistry major at Manhattan College, values the exposure to materials science, especially since she is not able to learn as much about it at her home institution.

“I learned a lot about crystallography and defects in materials through the MICRO curriculum, especially through videos,” says Garcia. “The research itself is very valuable, as well, because we get to apply what we’ve learned through the videos in the research we do remotely.”

Expanding research opportunities

From the beginning, the MICRO program was designed as a fully remote, rigorous education and mentoring program targeted toward students from underserved backgrounds interested in pursuing graduate school in materials science or related fields. Interns are matched with faculty to work on their specific research interests.

Jessica Sandland ’99, PhD ’05, principal lecturer in DMSE and co-founder of MICRO, says that research projects for the interns are designed to be work that they can do remotely, such as developing a machine-learning algorithm or a data analysis approach.

“It’s important to note that it’s not just about what the program and faculty are bringing to the student interns,” says Sandland, a member of the MIT Digital Learning Lab, a joint program between MIT Open Learning and the Institute’s academic departments. “The students are doing real research and work, and creating things of real value. It’s very much an exchange.”

Cécile Chazot PhD ’22, now an assistant professor of materials science and engineering at Northwestern University, had helped to establish MICRO at MIT from the very beginning. Once at Northwestern, she quickly realized that expanding MICRO to Northwestern would offer even more research opportunities to interns than by relying on MIT alone — leveraging the university’s strong materials science and engineering department, as well as offering resources for biomaterials research through Northwestern’s medical school. The program received funding from 3M and officially launched at Northwestern in fall 2023. Approximately half of the MICRO interns are now in the program with MIT and half are with Northwestern. Wood and Garcia both participate in the program via Northwestern.

“By expanding to another school, we’ve been able to have interns work with a much broader range of research projects,” says Chazot. “It has become easier for us to place students with faculty and research that match their interests.”

Building community

The MICRO program received a Higher Education Innovation grant from the Abdul Latif Jameel World Education Lab, part of MIT Open Learning, to develop an in-person summit. In January 2024, interns visited MIT for three days of presentations, workshops, and campus tours — including a tour of the MIT.nano building — as well as various community-building activities.

“A big part of MICRO is the community,” says Chazot. “A highlight of the summit was just seeing the students come together.”

The summit also included panel discussions that allowed interns to gain insights and advice from graduate students and professionals. The graduate panel discussion included MIT graduate students Sam Figueroa (mechanical engineering), Isabella Caruso (DMSE), and Eliana Feygin (DMSE). The career panel was led by Chazot and included Jatin Patil PhD ’23, head of product at SiTration; Maureen Reitman ’90, ScD ’93, group vice president and principal engineer at Exponent; Lucas Caretta PhD ’19, assistant professor of engineering at Brown University; Raquel D’Oyen ’90, who holds a PhD from Northwestern University and is a senior engineer at Raytheon; and Ashley Kaiser MS ’19, PhD ’21, senior process engineer at 6K.

Students also had an opportunity to share their work with each other through research presentations. Their presentations covered a wide range of topics, including: developing a computer program to calculate solubility parameters for polymers used in textile manufacturing; performing a life-cycle analysis of a photonic chip and evaluating its environmental impact in comparison to a standard silicon microchip; and applying machine learning algorithms to scanning transmission electron microscopy images of CrSBr, a two-dimensional magnetic material. 

“The summit was wonderful and the best academic experience I have had as a first-year college student,” says MICRO intern Gabriella La Cour, who is pursuing a major in chemistry and dual degree biomedical engineering at Spelman College and participates in MICRO through MIT. “I got to meet so many students who were all in grades above me … and I learned a little about how to navigate college as an upperclassman.” 

“I actually have an extremely close friendship with one of the students, and we keep in touch regularly,” adds La Cour. “Professor Chazot gave valuable advice about applications and recommendation letters that will be useful when I apply to REUs [Research Experiences for Undergraduates] and graduate schools.”

Looking to the future, MICRO organizers hope to continue to grow the program’s reach.

“We would love to see other schools taking on this model,” says Sandland. “There are a lot of opportunities out there. The more departments, research groups, and mentors that get involved with this program, the more impact it can have.”

Want to get middle-school kids excited about science? Let them do their own experiments on MIT.nano’s state-of-the-art microscopes — with guidelines and adult supervision, of course. That was the brainchild of Carl Thrasher and Tao Cai, MIT graduate students who spearheaded the Electron Microscopy Elevating Representation and Growth in Education (EMERGE) program.

Held in November, EMERGE invited 18 eighth-grade students to the pilot event at MIT.nano, an interdisciplinary facility for nanoscale research, to get hands-on experience in microscopy and materials science.

The highlight of the two-hour workshop: Each student explored mystery samples of everyday materials using one of two scanning electron microscopes (SEMs), which scan material samples using a beam of electrons to form an image. Though highly sophisticated, the instruments generated readily understandable data — images of intricate structures in a butterfly wing or a strand of hair, for example.

The students had an immediate, tangible sense of success, says Thrasher, from MIT’s Department of Materials Science and Engineering (DMSE). He led the program along with Cai, also from DMSE, and Collette Gordon, a grad student in the Department of Chemistry.

“This experience helped build a sense of agency and autonomy around this area of science, nurturing budding self-confidence among the students,” Thrasher says. “We didn’t give the students instructions, just empowered them to solve problems. When you don’t tell them the solution, you get really surprised with what they come up with.”

Unlocking interest in the infinitesimal

The students were part of a multi-year science and engineering exploration program called MITES Saturdays, run by MIT Introduction to Technology, Engineering, and Science, or MITES. A team of volunteers was on hand to help students follow the guidance set out by Thrasher, ensuring the careful handling of the SEMs — worth roughly $500,000 each.

MITES Saturdays program administrator Lynsey Ford was thrilled to observe the students’ autonomous exploration and enthusiasm.

“Our students got to meet real scientists who listened to them, cared about the questions they were asking, and welcomed them into a world of science,” Ford says. “A supportive learning environment can be just as powerful for science discovery as a half-million-dollar microscope.”

The pilot workshop was the first step for Thrasher and his team in their goal to build EMERGE into a program with broad impact, engaging middle-to-high school students from a variety of communities.

The partnership with MITES Saturdays is crucial for this endeavor, says Thrasher, providing a platform to reach a wider audience. “Seeing students from diverse backgrounds participating in EMERGE reinforces the profound difference science education can have.”

MITES Saturdays students are high-achieving Massachusetts seventh through 12th graders from Boston, MIT’s hometown of Cambridge, and nearby Lawrence.

“The majority of students who participate in our programs would be the first person in their family to go to college. A lot of them are from families balancing some sort of financial hardship, and from populations that are historically underrepresented in STEM,” Ford says.

Experienced SEM users set up the instruments and prepared test samples so students could take turns exploring specimens such as burrs, butterfly wings, computer chips, hair, and pollen by operating the microscope to adjust magnification, focus, and stage location.

Students left the EMERGE event with copies of the electron microscope images they generated. Thrasher hopes they will use these materials in follow-up projects, ideally integrating them into existing school curricula so students can share their experiences.

EMERGE co-director Cai says students were excited with their experimentation, both in being able to access such high-end equipment and in seeing what materials like Velcro look like under an SEM (spoiler alert: it’s spaghetti).

“We definitely saw a spark,” Cai says. “The subject matter was complex, but the students always wanted to know more.” And the after-program feedback was positive, with most saying the experience was fun and challenging. The volunteers noted how engaged the students were with the SEMs and subject matter. One volunteer overheard students say, “I felt like a real scientist!”

Inspiring tomorrow’s scientists

EMERGE is based on the Scanning Electron Microscopy Educators program, a long-running STEM outreach program started in 1991 by the Air Force Research Laboratory and adopted by Michigan State University. As an Air Force captain stationed at Wright-Patterson Air Force Base in Ohio, Thrasher participated in the program as a volunteer SEM expert.

“I thought it was an incredible opportunity for young students and wanted to bring it here to MIT,” he says.

The pilot was made possible thanks to support from the MITES Saturdays team and the Graduate Materials Council (GMC), the DMSE graduate student organization. Cai and DMSE grad student Jessica Dong, who are both GMC outreach chairs, helped fund, organize, and coordinate the event.

The MITES Saturdays students included reflections on their experience with the SEMs in their final presentations at the MITES Fall Symposium in November.

“My favorite part of the semester was using the SEM as it introduced me to microscopy at the level of electrons,” said one student.

“Our students had an incredible time with the EMERGE team. We’re excited about the possibility of future partnerships with MIT.nano and other departments at MIT, giving our scholars exposure to the breadth of opportunities as future scientists,” says Eboney Hearn, MITES executive director.

With the success of the pilot, the EMERGE team is looking to offer more programs to the MITES students in the spring. Anna Osherov is excited to give students more access to the cumulative staff knowledge and cutting-edge equipment at MIT.nano, which opened in 2018. Osherov is associate director for Characterization.nano, a shared experimental facility for advanced imaging and analysis.

“Our mission is to support mature researchers — and to help inspire the future PhDs and professors who will come to MIT to learn, research, and innovate,” Osherov says. “Designing and offering such programs, aimed at fostering natural curiosity and creativity of young minds, has a tremendous long-term benefit to our society. We can raise tomorrow’s generation in a better way.”

For her part, Ford is still coasting on the students’ excitement. “They come into the program so curious and hungry for knowledge. They remind me every day how amazing the world is.”

“How do we get to making nanomaterials that haven’t been evolved before?” asked Angela Belcher at the 2023 Mildred S. Dresselhaus Lecture at MIT on Nov. 20. “We can use elements that biology has already given us.”

The combined in-person and virtual audience of over 300 was treated to a light-up, 3D model of M13 bacteriophage, a virus that only infects bacteria, complete with a pull-out strand of DNA. Belcher used the feather-boa-like model to show how her research group modifies the M13’s genes to add new DNA and peptide sequences to template inorganic materials.

“I love controlling materials at the nanoscale using biology,” said Belcher, the James Mason Crafts Professor of Biological Engineering, materials science professor, and of the Koch Institute of Integrative Cancer Research at MIT. “We all know if you control materials at the nanoscale and you can start to tune them, then you can have all kinds of different applications.” And the opportunities are indeed vast — from building batteries, fuel cells, and solar cells to carbon sequestration and storage, environmental remediation, catalysis, and medical diagnostics and imaging.

Belcher sprinkled her talk with models and props, lined up on a table at the front of the 10-250 lecture hall, to demonstrate a wide variety of concepts and projects made possible by the intersection of biology and nanotechnology.

Energy storage and environment

“How do you go from a DNA sequence to a functioning battery?” posed Belcher. Grabbing a model of a large carbon nanotube, she explained how her group engineered a phage to pick up carbon nanotubes that would wind all the way around the virus and then fill in with different cathode or anode materials to make nanowires for battery electrodes.

How about using the M13 bacteriophage to improve the environment? Belcher referred to a project by former student Geran Zhang PhD ’19 that proved the virus can be modified for this context, too. He used the phage to template high-surface-area, carbon-based materials that can grab small molecules and break them down, Belcher said, opening a realm of possibilities from cleaning up rivers to developing chemical warfare agents to combating smog.

Belcher’s lab worked with the U.S. Army to produce protective clothing and masks made of these carbon-based virus nanofibers. “We went from five liters in our lab to a thousand liters, then 10,000 liters in the army labs where we’re able to make kilograms of the material,” Belcher said, stressing the importance of being able to test and prototype at scale.

Imaging tools and therapeutics in cancer

In the area of biomedical imaging, Belcher explained, a lot less is known in near-infrared imaging — imaging in wavelengths above 1,000 nanometers — than other imaging techniques, yet with near-infrared scientists can see much deeper inside the body. Belcher’s lab built their own systems to image at these wavelengths. The third generation of this system provides real-time, sub-millimeter optical imaging for guided surgery.

Working with Sangeeta Bhatia, the John J. and Dorothy Wilson Professor of Engineering, Belcher used carbon nanotubes to build imaging tools that find tiny tumors during surgery that doctors otherwise would not be able to see. The tool is actually a virus engineered to carry with it a fluorescent, single-walled carbon nanotube as it seeks out the tumors.

Nearing the end of her talk, Belcher presented a goal: to develop an accessible detection and diagnostic technology for ovarian cancer in five to 10 years.

“We think that we can do it,” Belcher said. She described her students’ work developing a way to scan an entire fallopian tube, as opposed to just one small portion, to find pre-cancer lesions, and talked about the team of MIT faculty, doctors, and researchers working collectively toward this goal.

“Part of the secret of life and the meaning of life is helping other people enjoy the passage of time,” said Belcher in her closing remarks. “I think that we can all do that by working to solve some of the biggest issues on the planet, including helping to diagnose and treat ovarian cancer early so people have more time to spend with their family.”

Honoring Mildred S. Dresselhaus

Belcher was the fifth speaker to deliver the Dresselhaus Lecture, an annual event organized by MIT.nano to honor the late MIT physics and electrical engineering Institute Professor Mildred Dresselhaus. The lecture features a speaker from anywhere in the world whose leadership and impact echo Dresselhaus’s life, accomplishments, and values.

“Millie was and is a huge hero of mine,” said Belcher. “Giving a lecture in Millie’s name is just the greatest honor.”

Belcher dedicated the talk to Dresselhaus, whom she described with an array of accolades — a trailblazer, a genius, an amazing mentor, teacher, and inventor. “Just knowing her was such a privilege,” she said.

Belcher also dedicated her talk to her own grandmother and mother, both of whom passed away from cancer, as well as late MIT professors Susan Lindquist and Angelika Amon, who both died of ovarian cancer.

“I’ve been so fortunate to work with just the most talented and dedicated graduate students, undergraduate students, postdocs, and researchers,” concluded Belcher. “It has been a pure joy to be in partnership with all of you to solve these very daunting problems.”

Want to get middle-school kids excited about science? Let them do their own experiments on MIT.nano’s state-of-the-art microscopes — with guidelines and adult supervision, of course. That was the brainchild of Carl Thrasher and Tao Cai, MIT graduate students who spearheaded the Electron Microscopy Elevating Representation and Growth in Education (EMERGE) program.

Held in November, EMERGE invited 18 eighth-grade students to the pilot event at MIT.nano, an interdisciplinary facility for nanoscale research, to get hands-on experience in microscopy and materials science.

The highlight of the two-hour workshop: Each student explored mystery samples of everyday materials using one of two scanning electron microscopes (SEMs), which scan material samples using a beam of electrons to form an image. Though highly sophisticated, the instruments generated readily understandable data — images of intricate structures in a butterfly wing or a strand of hair, for example.

The students had an immediate, tangible sense of success, says Thrasher, from MIT’s Department of Materials Science and Engineering (DMSE). He led the program along with Cai, also from DMSE, and Collette Gordon, a grad student in the Department of Chemistry.

“This experience helped build a sense of agency and autonomy around this area of science, nurturing budding self-confidence among the students,” Thrasher says. “We didn’t give the students instructions, just empowered them to solve problems. When you don’t tell them the solution, you get really surprised with what they come up with.”

Unlocking interest in the infinitesimal

The students were part of a multi-year science and engineering exploration program called MITES Saturdays, run by MIT Introduction to Technology, Engineering, and Science, or MITES. A team of volunteers was on hand to help students follow the guidance set out by Thrasher, ensuring the careful handling of the SEMs — worth roughly $500,000 each.

MITES Saturdays program administrator Lynsey Ford was thrilled to observe the students’ autonomous exploration and enthusiasm.

“Our students got to meet real scientists who listened to them, cared about the questions they were asking, and welcomed them into a world of science,” Ford says. “A supportive learning environment can be just as powerful for science discovery as a half-million-dollar microscope.”

The pilot workshop was the first step for Thrasher and his team in their goal to build EMERGE into a program with broad impact, engaging middle-to-high school students from a variety of communities.

The partnership with MITES Saturdays is crucial for this endeavor, says Thrasher, providing a platform to reach a wider audience. “Seeing students from diverse backgrounds participating in EMERGE reinforces the profound difference science education can have.”

MITES Saturdays students are high-achieving Massachusetts seventh through 12th graders from Boston, MIT’s hometown of Cambridge, and nearby Lawrence.

“The majority of students who participate in our programs would be the first person in their family to go to college. A lot of them are from families balancing some sort of financial hardship, and from populations that are historically underrepresented in STEM,” Ford says.

Experienced SEM users set up the instruments and prepared test samples so students could take turns exploring specimens such as burrs, butterfly wings, computer chips, hair, and pollen by operating the microscope to adjust magnification, focus, and stage location.

Students left the EMERGE event with copies of the electron microscope images they generated. Thrasher hopes they will use these materials in follow-up projects, ideally integrating them into existing school curricula so students can share their experiences.

EMERGE co-director Cai says students were excited with their experimentation, both in being able to access such high-end equipment and in seeing what materials like Velcro look like under an SEM (spoiler alert: it’s spaghetti).

“We definitely saw a spark,” Cai says. “The subject matter was complex, but the students always wanted to know more.” And the after-program feedback was positive, with most saying the experience was fun and challenging. The volunteers noted how engaged the students were with the SEMs and subject matter. One volunteer overheard students say, “I felt like a real scientist!”

Inspiring tomorrow’s scientists

EMERGE is based on the Scanning Electron Microscopy Educators program, a long-running STEM outreach program started in 1991 by the Air Force Research Laboratory and adopted by Michigan State University. As an Air Force captain stationed at Wright-Patterson Air Force Base in Ohio, Thrasher participated in the program as a volunteer SEM expert.

“I thought it was an incredible opportunity for young students and wanted to bring it here to MIT,” he says.

The pilot was made possible thanks to support from the MITES Saturdays team and the Graduate Materials Council (GMC), the DMSE graduate student organization. Cai and DMSE grad student Jessica Dong, who are both GMC outreach chairs, helped fund, organize, and coordinate the event.

The MITES Saturdays students included reflections on their experience with the SEMs in their final presentations at the MITES Fall Symposium in November.

“My favorite part of the semester was using the SEM as it introduced me to microscopy at the level of electrons,” said one student.

“Our students had an incredible time with the EMERGE team. We’re excited about the possibility of future partnerships with MIT.nano and other departments at MIT, giving our scholars exposure to the breadth of opportunities as future scientists,” says Eboney Hearn, MITES executive director.

With the success of the pilot, the EMERGE team is looking to offer more programs to the MITES students in the spring. Anna Osherov is excited to give students more access to the cumulative staff knowledge and cutting-edge equipment at MIT.nano, which opened in 2018. Osherov is associate director for Characterization.nano, a shared experimental facility for advanced imaging and analysis.

“Our mission is to support mature researchers — and to help inspire the future PhDs and professors who will come to MIT to learn, research, and innovate,” Osherov says. “Designing and offering such programs, aimed at fostering natural curiosity and creativity of young minds, has a tremendous long-term benefit to our society. We can raise tomorrow’s generation in a better way.”

For her part, Ford is still coasting on the students’ excitement. “They come into the program so curious and hungry for knowledge. They remind me every day how amazing the world is.”

“How do we get to making nanomaterials that haven’t been evolved before?” asked Angela Belcher at the 2023 Mildred S. Dresselhaus Lecture at MIT on Nov. 20. “We can use elements that biology has already given us.”

The combined in-person and virtual audience of over 300 was treated to a light-up, 3D model of M13 bacteriophage, a virus that only infects bacteria, complete with a pull-out strand of DNA. Belcher used the feather-boa-like model to show how her research group modifies the M13’s genes to add new DNA and peptide sequences to template inorganic materials.

“I love controlling materials at the nanoscale using biology,” said Belcher, the James Mason Crafts Professor of Biological Engineering, materials science professor, and of the Koch Institute of Integrative Cancer Research at MIT. “We all know if you control materials at the nanoscale and you can start to tune them, then you can have all kinds of different applications.” And the opportunities are indeed vast — from building batteries, fuel cells, and solar cells to carbon sequestration and storage, environmental remediation, catalysis, and medical diagnostics and imaging.

Belcher sprinkled her talk with models and props, lined up on a table at the front of the 10-250 lecture hall, to demonstrate a wide variety of concepts and projects made possible by the intersection of biology and nanotechnology.

Energy storage and environment

“How do you go from a DNA sequence to a functioning battery?” posed Belcher. Grabbing a model of a large carbon nanotube, she explained how her group engineered a phage to pick up carbon nanotubes that would wind all the way around the virus and then fill in with different cathode or anode materials to make nanowires for battery electrodes.

How about using the M13 bacteriophage to improve the environment? Belcher referred to a project by former student Geran Zhang PhD ’19 that proved the virus can be modified for this context, too. He used the phage to template high-surface-area, carbon-based materials that can grab small molecules and break them down, Belcher said, opening a realm of possibilities from cleaning up rivers to developing chemical warfare agents to combating smog.

Belcher’s lab worked with the U.S. Army to produce protective clothing and masks made of these carbon-based virus nanofibers. “We went from five liters in our lab to a thousand liters, then 10,000 liters in the army labs where we’re able to make kilograms of the material,” Belcher said, stressing the importance of being able to test and prototype at scale.

Imaging tools and therapeutics in cancer

In the area of biomedical imaging, Belcher explained, a lot less is known in near-infrared imaging — imaging in wavelengths above 1,000 nanometers — than other imaging techniques, yet with near-infrared scientists can see much deeper inside the body. Belcher’s lab built their own systems to image at these wavelengths. The third generation of this system provides real-time, sub-millimeter optical imaging for guided surgery.

Working with Sangeeta Bhatia, the John J. and Dorothy Wilson Professor of Engineering, Belcher used carbon nanotubes to build imaging tools that find tiny tumors during surgery that doctors otherwise would not be able to see. The tool is actually a virus engineered to carry with it a fluorescent, single-walled carbon nanotube as it seeks out the tumors.

Nearing the end of her talk, Belcher presented a goal: to develop an accessible detection and diagnostic technology for ovarian cancer in five to 10 years.

“We think that we can do it,” Belcher said. She described her students’ work developing a way to scan an entire fallopian tube, as opposed to just one small portion, to find pre-cancer lesions, and talked about the team of MIT faculty, doctors, and researchers working collectively toward this goal.

“Part of the secret of life and the meaning of life is helping other people enjoy the passage of time,” said Belcher in her closing remarks. “I think that we can all do that by working to solve some of the biggest issues on the planet, including helping to diagnose and treat ovarian cancer early so people have more time to spend with their family.”

Honoring Mildred S. Dresselhaus

Belcher was the fifth speaker to deliver the Dresselhaus Lecture, an annual event organized by MIT.nano to honor the late MIT physics and electrical engineering Institute Professor Mildred Dresselhaus. The lecture features a speaker from anywhere in the world whose leadership and impact echo Dresselhaus’s life, accomplishments, and values.

“Millie was and is a huge hero of mine,” said Belcher. “Giving a lecture in Millie’s name is just the greatest honor.”

Belcher dedicated the talk to Dresselhaus, whom she described with an array of accolades — a trailblazer, a genius, an amazing mentor, teacher, and inventor. “Just knowing her was such a privilege,” she said.

Belcher also dedicated her talk to her own grandmother and mother, both of whom passed away from cancer, as well as late MIT professors Susan Lindquist and Angelika Amon, who both died of ovarian cancer.

“I’ve been so fortunate to work with just the most talented and dedicated graduate students, undergraduate students, postdocs, and researchers,” concluded Belcher. “It has been a pure joy to be in partnership with all of you to solve these very daunting problems.”

Want to get middle-school kids excited about science? Let them do their own experiments on MIT.nano’s state-of-the-art microscopes — with guidelines and adult supervision, of course. That was the brainchild of Carl Thrasher and Tao Cai, MIT graduate students who spearheaded the Electron Microscopy Elevating Representation and Growth in Education (EMERGE) program.

Held in November, EMERGE invited 18 eighth-grade students to the pilot event at MIT.nano, an interdisciplinary facility for nanoscale research, to get hands-on experience in microscopy and materials science.

The highlight of the two-hour workshop: Each student explored mystery samples of everyday materials using one of two scanning electron microscopes (SEMs), which scan material samples using a beam of electrons to form an image. Though highly sophisticated, the instruments generated readily understandable data — images of intricate structures in a butterfly wing or a strand of hair, for example.

The students had an immediate, tangible sense of success, says Thrasher, from MIT’s Department of Materials Science and Engineering (DMSE). He led the program along with Cai, also from DMSE, and Collette Gordon, a grad student in the Department of Chemistry.

“This experience helped build a sense of agency and autonomy around this area of science, nurturing budding self-confidence among the students,” Thrasher says. “We didn’t give the students instructions, just empowered them to solve problems. When you don’t tell them the solution, you get really surprised with what they come up with.”

Unlocking interest in the infinitesimal

The students were part of a multi-year science and engineering exploration program called MITES Saturdays, run by MIT Introduction to Technology, Engineering, and Science, or MITES. A team of volunteers was on hand to help students follow the guidance set out by Thrasher, ensuring the careful handling of the SEMs — worth roughly $500,000 each.

MITES Saturdays program administrator Lynsey Ford was thrilled to observe the students’ autonomous exploration and enthusiasm.

“Our students got to meet real scientists who listened to them, cared about the questions they were asking, and welcomed them into a world of science,” Ford says. “A supportive learning environment can be just as powerful for science discovery as a half-million-dollar microscope.”

The pilot workshop was the first step for Thrasher and his team in their goal to build EMERGE into a program with broad impact, engaging middle-to-high school students from a variety of communities.

The partnership with MITES Saturdays is crucial for this endeavor, says Thrasher, providing a platform to reach a wider audience. “Seeing students from diverse backgrounds participating in EMERGE reinforces the profound difference science education can have.”

MITES Saturdays students are high-achieving Massachusetts seventh through 12th graders from Boston, MIT’s hometown of Cambridge, and nearby Lawrence.

“The majority of students who participate in our programs would be the first person in their family to go to college. A lot of them are from families balancing some sort of financial hardship, and from populations that are historically underrepresented in STEM,” Ford says.

Experienced SEM users set up the instruments and prepared test samples so students could take turns exploring specimens such as burrs, butterfly wings, computer chips, hair, and pollen by operating the microscope to adjust magnification, focus, and stage location.

Students left the EMERGE event with copies of the electron microscope images they generated. Thrasher hopes they will use these materials in follow-up projects, ideally integrating them into existing school curricula so students can share their experiences.

EMERGE co-director Cai says students were excited with their experimentation, both in being able to access such high-end equipment and in seeing what materials like Velcro look like under an SEM (spoiler alert: it’s spaghetti).

“We definitely saw a spark,” Cai says. “The subject matter was complex, but the students always wanted to know more.” And the after-program feedback was positive, with most saying the experience was fun and challenging. The volunteers noted how engaged the students were with the SEMs and subject matter. One volunteer overheard students say, “I felt like a real scientist!”

Inspiring tomorrow’s scientists

EMERGE is based on the Scanning Electron Microscopy Educators program, a long-running STEM outreach program started in 1991 by the Air Force Research Laboratory and adopted by Michigan State University. As an Air Force captain stationed at Wright-Patterson Air Force Base in Ohio, Thrasher participated in the program as a volunteer SEM expert.

“I thought it was an incredible opportunity for young students and wanted to bring it here to MIT,” he says.

The pilot was made possible thanks to support from the MITES Saturdays team and the Graduate Materials Council (GMC), the DMSE graduate student organization. Cai and DMSE grad student Jessica Dong, who are both GMC outreach chairs, helped fund, organize, and coordinate the event.

The MITES Saturdays students included reflections on their experience with the SEMs in their final presentations at the MITES Fall Symposium in November.

“My favorite part of the semester was using the SEM as it introduced me to microscopy at the level of electrons,” said one student.

“Our students had an incredible time with the EMERGE team. We’re excited about the possibility of future partnerships with MIT.nano and other departments at MIT, giving our scholars exposure to the breadth of opportunities as future scientists,” says Eboney Hearn, MITES executive director.

With the success of the pilot, the EMERGE team is looking to offer more programs to the MITES students in the spring. Anna Osherov is excited to give students more access to the cumulative staff knowledge and cutting-edge equipment at MIT.nano, which opened in 2018. Osherov is associate director for Characterization.nano, a shared experimental facility for advanced imaging and analysis.

“Our mission is to support mature researchers — and to help inspire the future PhDs and professors who will come to MIT to learn, research, and innovate,” Osherov says. “Designing and offering such programs, aimed at fostering natural curiosity and creativity of young minds, has a tremendous long-term benefit to our society. We can raise tomorrow’s generation in a better way.”

For her part, Ford is still coasting on the students’ excitement. “They come into the program so curious and hungry for knowledge. They remind me every day how amazing the world is.”

“How do we get to making nanomaterials that haven’t been evolved before?” asked Angela Belcher at the 2023 Mildred S. Dresselhaus Lecture at MIT on Nov. 20. “We can use elements that biology has already given us.”

The combined in-person and virtual audience of over 300 was treated to a light-up, 3D model of M13 bacteriophage, a virus that only infects bacteria, complete with a pull-out strand of DNA. Belcher used the feather-boa-like model to show how her research group modifies the M13’s genes to add new DNA and peptide sequences to template inorganic materials.

“I love controlling materials at the nanoscale using biology,” said Belcher, the James Mason Crafts Professor of Biological Engineering, materials science professor, and of the Koch Institute of Integrative Cancer Research at MIT. “We all know if you control materials at the nanoscale and you can start to tune them, then you can have all kinds of different applications.” And the opportunities are indeed vast — from building batteries, fuel cells, and solar cells to carbon sequestration and storage, environmental remediation, catalysis, and medical diagnostics and imaging.

Belcher sprinkled her talk with models and props, lined up on a table at the front of the 10-250 lecture hall, to demonstrate a wide variety of concepts and projects made possible by the intersection of biology and nanotechnology.

Energy storage and environment

“How do you go from a DNA sequence to a functioning battery?” posed Belcher. Grabbing a model of a large carbon nanotube, she explained how her group engineered a phage to pick up carbon nanotubes that would wind all the way around the virus and then fill in with different cathode or anode materials to make nanowires for battery electrodes.

How about using the M13 bacteriophage to improve the environment? Belcher referred to a project by former student Geran Zhang PhD ’19 that proved the virus can be modified for this context, too. He used the phage to template high-surface-area, carbon-based materials that can grab small molecules and break them down, Belcher said, opening a realm of possibilities from cleaning up rivers to developing chemical warfare agents to combating smog.

Belcher’s lab worked with the U.S. Army to produce protective clothing and masks made of these carbon-based virus nanofibers. “We went from five liters in our lab to a thousand liters, then 10,000 liters in the army labs where we’re able to make kilograms of the material,” Belcher said, stressing the importance of being able to test and prototype at scale.

Imaging tools and therapeutics in cancer

In the area of biomedical imaging, Belcher explained, a lot less is known in near-infrared imaging — imaging in wavelengths above 1,000 nanometers — than other imaging techniques, yet with near-infrared scientists can see much deeper inside the body. Belcher’s lab built their own systems to image at these wavelengths. The third generation of this system provides real-time, sub-millimeter optical imaging for guided surgery.

Working with Sangeeta Bhatia, the John J. and Dorothy Wilson Professor of Engineering, Belcher used carbon nanotubes to build imaging tools that find tiny tumors during surgery that doctors otherwise would not be able to see. The tool is actually a virus engineered to carry with it a fluorescent, single-walled carbon nanotube as it seeks out the tumors.

Nearing the end of her talk, Belcher presented a goal: to develop an accessible detection and diagnostic technology for ovarian cancer in five to 10 years.

“We think that we can do it,” Belcher said. She described her students’ work developing a way to scan an entire fallopian tube, as opposed to just one small portion, to find pre-cancer lesions, and talked about the team of MIT faculty, doctors, and researchers working collectively toward this goal.

“Part of the secret of life and the meaning of life is helping other people enjoy the passage of time,” said Belcher in her closing remarks. “I think that we can all do that by working to solve some of the biggest issues on the planet, including helping to diagnose and treat ovarian cancer early so people have more time to spend with their family.”

Honoring Mildred S. Dresselhaus

Belcher was the fifth speaker to deliver the Dresselhaus Lecture, an annual event organized by MIT.nano to honor the late MIT physics and electrical engineering Institute Professor Mildred Dresselhaus. The lecture features a speaker from anywhere in the world whose leadership and impact echo Dresselhaus’s life, accomplishments, and values.

“Millie was and is a huge hero of mine,” said Belcher. “Giving a lecture in Millie’s name is just the greatest honor.”

Belcher dedicated the talk to Dresselhaus, whom she described with an array of accolades — a trailblazer, a genius, an amazing mentor, teacher, and inventor. “Just knowing her was such a privilege,” she said.

Belcher also dedicated her talk to her own grandmother and mother, both of whom passed away from cancer, as well as late MIT professors Susan Lindquist and Angelika Amon, who both died of ovarian cancer.

“I’ve been so fortunate to work with just the most talented and dedicated graduate students, undergraduate students, postdocs, and researchers,” concluded Belcher. “It has been a pure joy to be in partnership with all of you to solve these very daunting problems.”

Want to get middle-school kids excited about science? Let them do their own experiments on MIT.nano’s state-of-the-art microscopes — with guidelines and adult supervision, of course. That was the brainchild of Carl Thrasher and Tao Cai, MIT graduate students who spearheaded the Electron Microscopy Elevating Representation and Growth in Education (EMERGE) program.

Held in November, EMERGE invited 18 eighth-grade students to the pilot event at MIT.nano, an interdisciplinary facility for nanoscale research, to get hands-on experience in microscopy and materials science.

The highlight of the two-hour workshop: Each student explored mystery samples of everyday materials using one of two scanning electron microscopes (SEMs), which scan material samples using a beam of electrons to form an image. Though highly sophisticated, the instruments generated readily understandable data — images of intricate structures in a butterfly wing or a strand of hair, for example.

The students had an immediate, tangible sense of success, says Thrasher, from MIT’s Department of Materials Science and Engineering (DMSE). He led the program along with Cai, also from DMSE, and Collette Gordon, a grad student in the Department of Chemistry.

“This experience helped build a sense of agency and autonomy around this area of science, nurturing budding self-confidence among the students,” Thrasher says. “We didn’t give the students instructions, just empowered them to solve problems. When you don’t tell them the solution, you get really surprised with what they come up with.”

Unlocking interest in the infinitesimal

The students were part of a multi-year science and engineering exploration program called MITES Saturdays, run by MIT Introduction to Technology, Engineering, and Science, or MITES. A team of volunteers was on hand to help students follow the guidance set out by Thrasher, ensuring the careful handling of the SEMs — worth roughly $500,000 each.

MITES Saturdays program administrator Lynsey Ford was thrilled to observe the students’ autonomous exploration and enthusiasm.

“Our students got to meet real scientists who listened to them, cared about the questions they were asking, and welcomed them into a world of science,” Ford says. “A supportive learning environment can be just as powerful for science discovery as a half-million-dollar microscope.”

The pilot workshop was the first step for Thrasher and his team in their goal to build EMERGE into a program with broad impact, engaging middle-to-high school students from a variety of communities.

The partnership with MITES Saturdays is crucial for this endeavor, says Thrasher, providing a platform to reach a wider audience. “Seeing students from diverse backgrounds participating in EMERGE reinforces the profound difference science education can have.”

MITES Saturdays students are high-achieving Massachusetts seventh through 12th graders from Boston, MIT’s hometown of Cambridge, and nearby Lawrence.

“The majority of students who participate in our programs would be the first person in their family to go to college. A lot of them are from families balancing some sort of financial hardship, and from populations that are historically underrepresented in STEM,” Ford says.

Experienced SEM users set up the instruments and prepared test samples so students could take turns exploring specimens such as burrs, butterfly wings, computer chips, hair, and pollen by operating the microscope to adjust magnification, focus, and stage location.

Students left the EMERGE event with copies of the electron microscope images they generated. Thrasher hopes they will use these materials in follow-up projects, ideally integrating them into existing school curricula so students can share their experiences.

EMERGE co-director Cai says students were excited with their experimentation, both in being able to access such high-end equipment and in seeing what materials like Velcro look like under an SEM (spoiler alert: it’s spaghetti).

“We definitely saw a spark,” Cai says. “The subject matter was complex, but the students always wanted to know more.” And the after-program feedback was positive, with most saying the experience was fun and challenging. The volunteers noted how engaged the students were with the SEMs and subject matter. One volunteer overheard students say, “I felt like a real scientist!”

Inspiring tomorrow’s scientists

EMERGE is based on the Scanning Electron Microscopy Educators program, a long-running STEM outreach program started in 1991 by the Air Force Research Laboratory and adopted by Michigan State University. As an Air Force captain stationed at Wright-Patterson Air Force Base in Ohio, Thrasher participated in the program as a volunteer SEM expert.

“I thought it was an incredible opportunity for young students and wanted to bring it here to MIT,” he says.

The pilot was made possible thanks to support from the MITES Saturdays team and the Graduate Materials Council (GMC), the DMSE graduate student organization. Cai and DMSE grad student Jessica Dong, who are both GMC outreach chairs, helped fund, organize, and coordinate the event.

The MITES Saturdays students included reflections on their experience with the SEMs in their final presentations at the MITES Fall Symposium in November.

“My favorite part of the semester was using the SEM as it introduced me to microscopy at the level of electrons,” said one student.

“Our students had an incredible time with the EMERGE team. We’re excited about the possibility of future partnerships with MIT.nano and other departments at MIT, giving our scholars exposure to the breadth of opportunities as future scientists,” says Eboney Hearn, MITES executive director.

With the success of the pilot, the EMERGE team is looking to offer more programs to the MITES students in the spring. Anna Osherov is excited to give students more access to the cumulative staff knowledge and cutting-edge equipment at MIT.nano, which opened in 2018. Osherov is associate director for Characterization.nano, a shared experimental facility for advanced imaging and analysis.

“Our mission is to support mature researchers — and to help inspire the future PhDs and professors who will come to MIT to learn, research, and innovate,” Osherov says. “Designing and offering such programs, aimed at fostering natural curiosity and creativity of young minds, has a tremendous long-term benefit to our society. We can raise tomorrow’s generation in a better way.”

For her part, Ford is still coasting on the students’ excitement. “They come into the program so curious and hungry for knowledge. They remind me every day how amazing the world is.”

“How do we get to making nanomaterials that haven’t been evolved before?” asked Angela Belcher at the 2023 Mildred S. Dresselhaus Lecture at MIT on Nov. 20. “We can use elements that biology has already given us.”

The combined in-person and virtual audience of over 300 was treated to a light-up, 3D model of M13 bacteriophage, a virus that only infects bacteria, complete with a pull-out strand of DNA. Belcher used the feather-boa-like model to show how her research group modifies the M13’s genes to add new DNA and peptide sequences to template inorganic materials.

“I love controlling materials at the nanoscale using biology,” said Belcher, the James Mason Crafts Professor of Biological Engineering, materials science professor, and of the Koch Institute of Integrative Cancer Research at MIT. “We all know if you control materials at the nanoscale and you can start to tune them, then you can have all kinds of different applications.” And the opportunities are indeed vast — from building batteries, fuel cells, and solar cells to carbon sequestration and storage, environmental remediation, catalysis, and medical diagnostics and imaging.

Belcher sprinkled her talk with models and props, lined up on a table at the front of the 10-250 lecture hall, to demonstrate a wide variety of concepts and projects made possible by the intersection of biology and nanotechnology.

Energy storage and environment

“How do you go from a DNA sequence to a functioning battery?” posed Belcher. Grabbing a model of a large carbon nanotube, she explained how her group engineered a phage to pick up carbon nanotubes that would wind all the way around the virus and then fill in with different cathode or anode materials to make nanowires for battery electrodes.

How about using the M13 bacteriophage to improve the environment? Belcher referred to a project by former student Geran Zhang PhD ’19 that proved the virus can be modified for this context, too. He used the phage to template high-surface-area, carbon-based materials that can grab small molecules and break them down, Belcher said, opening a realm of possibilities from cleaning up rivers to developing chemical warfare agents to combating smog.

Belcher’s lab worked with the U.S. Army to produce protective clothing and masks made of these carbon-based virus nanofibers. “We went from five liters in our lab to a thousand liters, then 10,000 liters in the army labs where we’re able to make kilograms of the material,” Belcher said, stressing the importance of being able to test and prototype at scale.

Imaging tools and therapeutics in cancer

In the area of biomedical imaging, Belcher explained, a lot less is known in near-infrared imaging — imaging in wavelengths above 1,000 nanometers — than other imaging techniques, yet with near-infrared scientists can see much deeper inside the body. Belcher’s lab built their own systems to image at these wavelengths. The third generation of this system provides real-time, sub-millimeter optical imaging for guided surgery.

Working with Sangeeta Bhatia, the John J. and Dorothy Wilson Professor of Engineering, Belcher used carbon nanotubes to build imaging tools that find tiny tumors during surgery that doctors otherwise would not be able to see. The tool is actually a virus engineered to carry with it a fluorescent, single-walled carbon nanotube as it seeks out the tumors.

Nearing the end of her talk, Belcher presented a goal: to develop an accessible detection and diagnostic technology for ovarian cancer in five to 10 years.

“We think that we can do it,” Belcher said. She described her students’ work developing a way to scan an entire fallopian tube, as opposed to just one small portion, to find pre-cancer lesions, and talked about the team of MIT faculty, doctors, and researchers working collectively toward this goal.

“Part of the secret of life and the meaning of life is helping other people enjoy the passage of time,” said Belcher in her closing remarks. “I think that we can all do that by working to solve some of the biggest issues on the planet, including helping to diagnose and treat ovarian cancer early so people have more time to spend with their family.”

Honoring Mildred S. Dresselhaus

Belcher was the fifth speaker to deliver the Dresselhaus Lecture, an annual event organized by MIT.nano to honor the late MIT physics and electrical engineering Institute Professor Mildred Dresselhaus. The lecture features a speaker from anywhere in the world whose leadership and impact echo Dresselhaus’s life, accomplishments, and values.

“Millie was and is a huge hero of mine,” said Belcher. “Giving a lecture in Millie’s name is just the greatest honor.”

Belcher dedicated the talk to Dresselhaus, whom she described with an array of accolades — a trailblazer, a genius, an amazing mentor, teacher, and inventor. “Just knowing her was such a privilege,” she said.

Belcher also dedicated her talk to her own grandmother and mother, both of whom passed away from cancer, as well as late MIT professors Susan Lindquist and Angelika Amon, who both died of ovarian cancer.

“I’ve been so fortunate to work with just the most talented and dedicated graduate students, undergraduate students, postdocs, and researchers,” concluded Belcher. “It has been a pure joy to be in partnership with all of you to solve these very daunting problems.”

Want to get middle-school kids excited about science? Let them do their own experiments on MIT.nano’s state-of-the-art microscopes — with guidelines and adult supervision, of course. That was the brainchild of Carl Thrasher and Tao Cai, MIT graduate students who spearheaded the Electron Microscopy Elevating Representation and Growth in Education (EMERGE) program.

Held in November, EMERGE invited 18 eighth-grade students to the pilot event at MIT.nano, an interdisciplinary facility for nanoscale research, to get hands-on experience in microscopy and materials science.

The highlight of the two-hour workshop: Each student explored mystery samples of everyday materials using one of two scanning electron microscopes (SEMs), which scan material samples using a beam of electrons to form an image. Though highly sophisticated, the instruments generated readily understandable data — images of intricate structures in a butterfly wing or a strand of hair, for example.

The students had an immediate, tangible sense of success, says Thrasher, from MIT’s Department of Materials Science and Engineering (DMSE). He led the program along with Cai, also from DMSE, and Collette Gordon, a grad student in the Department of Chemistry.

“This experience helped build a sense of agency and autonomy around this area of science, nurturing budding self-confidence among the students,” Thrasher says. “We didn’t give the students instructions, just empowered them to solve problems. When you don’t tell them the solution, you get really surprised with what they come up with.”

Unlocking interest in the infinitesimal

The students were part of a multi-year science and engineering exploration program called MITES Saturdays, run by MIT Introduction to Technology, Engineering, and Science, or MITES. A team of volunteers was on hand to help students follow the guidance set out by Thrasher, ensuring the careful handling of the SEMs — worth roughly $500,000 each.

MITES Saturdays program administrator Lynsey Ford was thrilled to observe the students’ autonomous exploration and enthusiasm.

“Our students got to meet real scientists who listened to them, cared about the questions they were asking, and welcomed them into a world of science,” Ford says. “A supportive learning environment can be just as powerful for science discovery as a half-million-dollar microscope.”

The pilot workshop was the first step for Thrasher and his team in their goal to build EMERGE into a program with broad impact, engaging middle-to-high school students from a variety of communities.

The partnership with MITES Saturdays is crucial for this endeavor, says Thrasher, providing a platform to reach a wider audience. “Seeing students from diverse backgrounds participating in EMERGE reinforces the profound difference science education can have.”

MITES Saturdays students are high-achieving Massachusetts seventh through 12th graders from Boston, MIT’s hometown of Cambridge, and nearby Lawrence.

“The majority of students who participate in our programs would be the first person in their family to go to college. A lot of them are from families balancing some sort of financial hardship, and from populations that are historically underrepresented in STEM,” Ford says.

Experienced SEM users set up the instruments and prepared test samples so students could take turns exploring specimens such as burrs, butterfly wings, computer chips, hair, and pollen by operating the microscope to adjust magnification, focus, and stage location.

Students left the EMERGE event with copies of the electron microscope images they generated. Thrasher hopes they will use these materials in follow-up projects, ideally integrating them into existing school curricula so students can share their experiences.

EMERGE co-director Cai says students were excited with their experimentation, both in being able to access such high-end equipment and in seeing what materials like Velcro look like under an SEM (spoiler alert: it’s spaghetti).

“We definitely saw a spark,” Cai says. “The subject matter was complex, but the students always wanted to know more.” And the after-program feedback was positive, with most saying the experience was fun and challenging. The volunteers noted how engaged the students were with the SEMs and subject matter. One volunteer overheard students say, “I felt like a real scientist!”

Inspiring tomorrow’s scientists

EMERGE is based on the Scanning Electron Microscopy Educators program, a long-running STEM outreach program started in 1991 by the Air Force Research Laboratory and adopted by Michigan State University. As an Air Force captain stationed at Wright-Patterson Air Force Base in Ohio, Thrasher participated in the program as a volunteer SEM expert.

“I thought it was an incredible opportunity for young students and wanted to bring it here to MIT,” he says.

The pilot was made possible thanks to support from the MITES Saturdays team and the Graduate Materials Council (GMC), the DMSE graduate student organization. Cai and DMSE grad student Jessica Dong, who are both GMC outreach chairs, helped fund, organize, and coordinate the event.

The MITES Saturdays students included reflections on their experience with the SEMs in their final presentations at the MITES Fall Symposium in November.

“My favorite part of the semester was using the SEM as it introduced me to microscopy at the level of electrons,” said one student.

“Our students had an incredible time with the EMERGE team. We’re excited about the possibility of future partnerships with MIT.nano and other departments at MIT, giving our scholars exposure to the breadth of opportunities as future scientists,” says Eboney Hearn, MITES executive director.

With the success of the pilot, the EMERGE team is looking to offer more programs to the MITES students in the spring. Anna Osherov is excited to give students more access to the cumulative staff knowledge and cutting-edge equipment at MIT.nano, which opened in 2018. Osherov is associate director for Characterization.nano, a shared experimental facility for advanced imaging and analysis.

“Our mission is to support mature researchers — and to help inspire the future PhDs and professors who will come to MIT to learn, research, and innovate,” Osherov says. “Designing and offering such programs, aimed at fostering natural curiosity and creativity of young minds, has a tremendous long-term benefit to our society. We can raise tomorrow’s generation in a better way.”

For her part, Ford is still coasting on the students’ excitement. “They come into the program so curious and hungry for knowledge. They remind me every day how amazing the world is.”

“How do we get to making nanomaterials that haven’t been evolved before?” asked Angela Belcher at the 2023 Mildred S. Dresselhaus Lecture at MIT on Nov. 20. “We can use elements that biology has already given us.”

The combined in-person and virtual audience of over 300 was treated to a light-up, 3D model of M13 bacteriophage, a virus that only infects bacteria, complete with a pull-out strand of DNA. Belcher used the feather-boa-like model to show how her research group modifies the M13’s genes to add new DNA and peptide sequences to template inorganic materials.

“I love controlling materials at the nanoscale using biology,” said Belcher, the James Mason Crafts Professor of Biological Engineering, materials science professor, and of the Koch Institute of Integrative Cancer Research at MIT. “We all know if you control materials at the nanoscale and you can start to tune them, then you can have all kinds of different applications.” And the opportunities are indeed vast — from building batteries, fuel cells, and solar cells to carbon sequestration and storage, environmental remediation, catalysis, and medical diagnostics and imaging.

Belcher sprinkled her talk with models and props, lined up on a table at the front of the 10-250 lecture hall, to demonstrate a wide variety of concepts and projects made possible by the intersection of biology and nanotechnology.

Energy storage and environment

“How do you go from a DNA sequence to a functioning battery?” posed Belcher. Grabbing a model of a large carbon nanotube, she explained how her group engineered a phage to pick up carbon nanotubes that would wind all the way around the virus and then fill in with different cathode or anode materials to make nanowires for battery electrodes.

How about using the M13 bacteriophage to improve the environment? Belcher referred to a project by former student Geran Zhang PhD ’19 that proved the virus can be modified for this context, too. He used the phage to template high-surface-area, carbon-based materials that can grab small molecules and break them down, Belcher said, opening a realm of possibilities from cleaning up rivers to developing chemical warfare agents to combating smog.

Belcher’s lab worked with the U.S. Army to produce protective clothing and masks made of these carbon-based virus nanofibers. “We went from five liters in our lab to a thousand liters, then 10,000 liters in the army labs where we’re able to make kilograms of the material,” Belcher said, stressing the importance of being able to test and prototype at scale.

Imaging tools and therapeutics in cancer

In the area of biomedical imaging, Belcher explained, a lot less is known in near-infrared imaging — imaging in wavelengths above 1,000 nanometers — than other imaging techniques, yet with near-infrared scientists can see much deeper inside the body. Belcher’s lab built their own systems to image at these wavelengths. The third generation of this system provides real-time, sub-millimeter optical imaging for guided surgery.

Working with Sangeeta Bhatia, the John J. and Dorothy Wilson Professor of Engineering, Belcher used carbon nanotubes to build imaging tools that find tiny tumors during surgery that doctors otherwise would not be able to see. The tool is actually a virus engineered to carry with it a fluorescent, single-walled carbon nanotube as it seeks out the tumors.

Nearing the end of her talk, Belcher presented a goal: to develop an accessible detection and diagnostic technology for ovarian cancer in five to 10 years.

“We think that we can do it,” Belcher said. She described her students’ work developing a way to scan an entire fallopian tube, as opposed to just one small portion, to find pre-cancer lesions, and talked about the team of MIT faculty, doctors, and researchers working collectively toward this goal.

“Part of the secret of life and the meaning of life is helping other people enjoy the passage of time,” said Belcher in her closing remarks. “I think that we can all do that by working to solve some of the biggest issues on the planet, including helping to diagnose and treat ovarian cancer early so people have more time to spend with their family.”

Honoring Mildred S. Dresselhaus

Belcher was the fifth speaker to deliver the Dresselhaus Lecture, an annual event organized by MIT.nano to honor the late MIT physics and electrical engineering Institute Professor Mildred Dresselhaus. The lecture features a speaker from anywhere in the world whose leadership and impact echo Dresselhaus’s life, accomplishments, and values.

“Millie was and is a huge hero of mine,” said Belcher. “Giving a lecture in Millie’s name is just the greatest honor.”

Belcher dedicated the talk to Dresselhaus, whom she described with an array of accolades — a trailblazer, a genius, an amazing mentor, teacher, and inventor. “Just knowing her was such a privilege,” she said.

Belcher also dedicated her talk to her own grandmother and mother, both of whom passed away from cancer, as well as late MIT professors Susan Lindquist and Angelika Amon, who both died of ovarian cancer.

“I’ve been so fortunate to work with just the most talented and dedicated graduate students, undergraduate students, postdocs, and researchers,” concluded Belcher. “It has been a pure joy to be in partnership with all of you to solve these very daunting problems.”

Want to get middle-school kids excited about science? Let them do their own experiments on MIT.nano’s state-of-the-art microscopes — with guidelines and adult supervision, of course. That was the brainchild of Carl Thrasher and Tao Cai, MIT graduate students who spearheaded the Electron Microscopy Elevating Representation and Growth in Education (EMERGE) program.

Held in November, EMERGE invited 18 eighth-grade students to the pilot event at MIT.nano, an interdisciplinary facility for nanoscale research, to get hands-on experience in microscopy and materials science.

The highlight of the two-hour workshop: Each student explored mystery samples of everyday materials using one of two scanning electron microscopes (SEMs), which scan material samples using a beam of electrons to form an image. Though highly sophisticated, the instruments generated readily understandable data — images of intricate structures in a butterfly wing or a strand of hair, for example.

The students had an immediate, tangible sense of success, says Thrasher, from MIT’s Department of Materials Science and Engineering (DMSE). He led the program along with Cai, also from DMSE, and Collette Gordon, a grad student in the Department of Chemistry.

“This experience helped build a sense of agency and autonomy around this area of science, nurturing budding self-confidence among the students,” Thrasher says. “We didn’t give the students instructions, just empowered them to solve problems. When you don’t tell them the solution, you get really surprised with what they come up with.”

Unlocking interest in the infinitesimal

The students were part of a multi-year science and engineering exploration program called MITES Saturdays, run by MIT Introduction to Technology, Engineering, and Science, or MITES. A team of volunteers was on hand to help students follow the guidance set out by Thrasher, ensuring the careful handling of the SEMs — worth roughly $500,000 each.

MITES Saturdays program administrator Lynsey Ford was thrilled to observe the students’ autonomous exploration and enthusiasm.

“Our students got to meet real scientists who listened to them, cared about the questions they were asking, and welcomed them into a world of science,” Ford says. “A supportive learning environment can be just as powerful for science discovery as a half-million-dollar microscope.”

The pilot workshop was the first step for Thrasher and his team in their goal to build EMERGE into a program with broad impact, engaging middle-to-high school students from a variety of communities.

The partnership with MITES Saturdays is crucial for this endeavor, says Thrasher, providing a platform to reach a wider audience. “Seeing students from diverse backgrounds participating in EMERGE reinforces the profound difference science education can have.”

MITES Saturdays students are high-achieving Massachusetts seventh through 12th graders from Boston, MIT’s hometown of Cambridge, and nearby Lawrence.

“The majority of students who participate in our programs would be the first person in their family to go to college. A lot of them are from families balancing some sort of financial hardship, and from populations that are historically underrepresented in STEM,” Ford says.

Experienced SEM users set up the instruments and prepared test samples so students could take turns exploring specimens such as burrs, butterfly wings, computer chips, hair, and pollen by operating the microscope to adjust magnification, focus, and stage location.

Students left the EMERGE event with copies of the electron microscope images they generated. Thrasher hopes they will use these materials in follow-up projects, ideally integrating them into existing school curricula so students can share their experiences.

EMERGE co-director Cai says students were excited with their experimentation, both in being able to access such high-end equipment and in seeing what materials like Velcro look like under an SEM (spoiler alert: it’s spaghetti).

“We definitely saw a spark,” Cai says. “The subject matter was complex, but the students always wanted to know more.” And the after-program feedback was positive, with most saying the experience was fun and challenging. The volunteers noted how engaged the students were with the SEMs and subject matter. One volunteer overheard students say, “I felt like a real scientist!”

Inspiring tomorrow’s scientists

EMERGE is based on the Scanning Electron Microscopy Educators program, a long-running STEM outreach program started in 1991 by the Air Force Research Laboratory and adopted by Michigan State University. As an Air Force captain stationed at Wright-Patterson Air Force Base in Ohio, Thrasher participated in the program as a volunteer SEM expert.

“I thought it was an incredible opportunity for young students and wanted to bring it here to MIT,” he says.

The pilot was made possible thanks to support from the MITES Saturdays team and the Graduate Materials Council (GMC), the DMSE graduate student organization. Cai and DMSE grad student Jessica Dong, who are both GMC outreach chairs, helped fund, organize, and coordinate the event.

The MITES Saturdays students included reflections on their experience with the SEMs in their final presentations at the MITES Fall Symposium in November.

“My favorite part of the semester was using the SEM as it introduced me to microscopy at the level of electrons,” said one student.

“Our students had an incredible time with the EMERGE team. We’re excited about the possibility of future partnerships with MIT.nano and other departments at MIT, giving our scholars exposure to the breadth of opportunities as future scientists,” says Eboney Hearn, MITES executive director.

With the success of the pilot, the EMERGE team is looking to offer more programs to the MITES students in the spring. Anna Osherov is excited to give students more access to the cumulative staff knowledge and cutting-edge equipment at MIT.nano, which opened in 2018. Osherov is associate director for Characterization.nano, a shared experimental facility for advanced imaging and analysis.

“Our mission is to support mature researchers — and to help inspire the future PhDs and professors who will come to MIT to learn, research, and innovate,” Osherov says. “Designing and offering such programs, aimed at fostering natural curiosity and creativity of young minds, has a tremendous long-term benefit to our society. We can raise tomorrow’s generation in a better way.”

For her part, Ford is still coasting on the students’ excitement. “They come into the program so curious and hungry for knowledge. They remind me every day how amazing the world is.”

“How do we get to making nanomaterials that haven’t been evolved before?” asked Angela Belcher at the 2023 Mildred S. Dresselhaus Lecture at MIT on Nov. 20. “We can use elements that biology has already given us.”

The combined in-person and virtual audience of over 300 was treated to a light-up, 3D model of M13 bacteriophage, a virus that only infects bacteria, complete with a pull-out strand of DNA. Belcher used the feather-boa-like model to show how her research group modifies the M13’s genes to add new DNA and peptide sequences to template inorganic materials.

“I love controlling materials at the nanoscale using biology,” said Belcher, the James Mason Crafts Professor of Biological Engineering, materials science professor, and of the Koch Institute of Integrative Cancer Research at MIT. “We all know if you control materials at the nanoscale and you can start to tune them, then you can have all kinds of different applications.” And the opportunities are indeed vast — from building batteries, fuel cells, and solar cells to carbon sequestration and storage, environmental remediation, catalysis, and medical diagnostics and imaging.

Belcher sprinkled her talk with models and props, lined up on a table at the front of the 10-250 lecture hall, to demonstrate a wide variety of concepts and projects made possible by the intersection of biology and nanotechnology.

Energy storage and environment

“How do you go from a DNA sequence to a functioning battery?” posed Belcher. Grabbing a model of a large carbon nanotube, she explained how her group engineered a phage to pick up carbon nanotubes that would wind all the way around the virus and then fill in with different cathode or anode materials to make nanowires for battery electrodes.

How about using the M13 bacteriophage to improve the environment? Belcher referred to a project by former student Geran Zhang PhD ’19 that proved the virus can be modified for this context, too. He used the phage to template high-surface-area, carbon-based materials that can grab small molecules and break them down, Belcher said, opening a realm of possibilities from cleaning up rivers to developing chemical warfare agents to combating smog.

Belcher’s lab worked with the U.S. Army to produce protective clothing and masks made of these carbon-based virus nanofibers. “We went from five liters in our lab to a thousand liters, then 10,000 liters in the army labs where we’re able to make kilograms of the material,” Belcher said, stressing the importance of being able to test and prototype at scale.

Imaging tools and therapeutics in cancer

In the area of biomedical imaging, Belcher explained, a lot less is known in near-infrared imaging — imaging in wavelengths above 1,000 nanometers — than other imaging techniques, yet with near-infrared scientists can see much deeper inside the body. Belcher’s lab built their own systems to image at these wavelengths. The third generation of this system provides real-time, sub-millimeter optical imaging for guided surgery.

Working with Sangeeta Bhatia, the John J. and Dorothy Wilson Professor of Engineering, Belcher used carbon nanotubes to build imaging tools that find tiny tumors during surgery that doctors otherwise would not be able to see. The tool is actually a virus engineered to carry with it a fluorescent, single-walled carbon nanotube as it seeks out the tumors.

Nearing the end of her talk, Belcher presented a goal: to develop an accessible detection and diagnostic technology for ovarian cancer in five to 10 years.

“We think that we can do it,” Belcher said. She described her students’ work developing a way to scan an entire fallopian tube, as opposed to just one small portion, to find pre-cancer lesions, and talked about the team of MIT faculty, doctors, and researchers working collectively toward this goal.

“Part of the secret of life and the meaning of life is helping other people enjoy the passage of time,” said Belcher in her closing remarks. “I think that we can all do that by working to solve some of the biggest issues on the planet, including helping to diagnose and treat ovarian cancer early so people have more time to spend with their family.”

Honoring Mildred S. Dresselhaus

Belcher was the fifth speaker to deliver the Dresselhaus Lecture, an annual event organized by MIT.nano to honor the late MIT physics and electrical engineering Institute Professor Mildred Dresselhaus. The lecture features a speaker from anywhere in the world whose leadership and impact echo Dresselhaus’s life, accomplishments, and values.

“Millie was and is a huge hero of mine,” said Belcher. “Giving a lecture in Millie’s name is just the greatest honor.”

Belcher dedicated the talk to Dresselhaus, whom she described with an array of accolades — a trailblazer, a genius, an amazing mentor, teacher, and inventor. “Just knowing her was such a privilege,” she said.

Belcher also dedicated her talk to her own grandmother and mother, both of whom passed away from cancer, as well as late MIT professors Susan Lindquist and Angelika Amon, who both died of ovarian cancer.

“I’ve been so fortunate to work with just the most talented and dedicated graduate students, undergraduate students, postdocs, and researchers,” concluded Belcher. “It has been a pure joy to be in partnership with all of you to solve these very daunting problems.”